LOCUS       NZ_DS981517            40688 bp    DNA     linear   CON 30-MAR-2017
DEFINITION  Clostridium sporogenes ATCC 15579 Scfld_02_0, whole genome shotgun
            sequence.
ACCESSION   NZ_DS981517
VERSION     NZ_DS981517.1
KEYWORDS    .
SOURCE      Clostridium sporogenes ATCC 15579
  ORGANISM  Clostridium sporogenes ATCC 15579
            Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
            Clostridium.
COMMENT     REFSEQ INFORMATION: The reference sequence was derived from
            DS981517.
            Clostridium sporogenes (GenBank Accession Number for 16S rDNA gene:
            DQ911258*) is a member of the Firmicutes division of the domain
            bacteria and has been isolated from human feces. The sequenced
            strain was obtained from ATCC (ATCC 15579).
            We have collected 8.9X coverage in plasmid end reads and 454 reads.
            We have performed one round of automated sequence
            improvement(pre-finishing), along with manual improvement that
            includes breaking apart any mis-assembly, and making manual joins
            where possible. Manual edits also are made where the consensus
            appears to be incorrect. All low quality data on the ends of
            contigs is removed. Contigs are ordered and oriented where
            possible.
            Sequencing/Assembly: The genomic DNA was purified from liquid
            culture derived from a single bacterial colony. A hybrid sequencing
            strategy that utilized reads from both 454 GS-20 and ABI 3730xl
            sequencers was devised and implemented to generate the draft genome
            sequences. 454 reads were assembled using Newbler (454 Life
            Sciences) into 454 de novo contigs.These de novo contigs were
            converted in silico to 800 base paired reads ('superreads') with
            400 base overlaps with neighboring superreads. Finally, PCAP
            (Huang, et al, Genome Research, 13:2164, (2003)) was used to
            assemble the super-reads and the conventional 3730xl capillary
            reads.
            This sequenced strain is part of a comprehensive, sequence-based
            survey of members of the normal human gutmicrobiota.  A joint
            effort of the WU-GSC and the Center for Genome Sciences at
            Washington University School of Medicine, the purpose of this
            survey is to provide the general scientific community with a broad
            view of the gene content of 100 representativesof the major
            divisions represented in the intestine's microbial community. This
            information should provide a frame of reference for analyzing
            metagenomic studies of the human gut microbiome. Further details of
            this effort are described in a white paper entitled 'Extending Our
            View of Self: the Human Gut Microbiome Initiative (HGMI)'
            (http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMIS
            eq.pdf). These studies are supported by National Human Genome
            Research Institute.
            Coding sequences were predicted using GeneMark v3.3 and Glimmer2
            v2.13. Intergenic regions not spanned by GeneMark and Glimmer2 were
            blasted against NCBI's non-redundant (NR)  database and predictions
            generated based on protein alignments. tRNA genes were determined
            using tRNAscan-SE 1.23 and non-coding RNA genes by RNAmmer-1.2 and
            Rfam v8.0. Gene names are generated at the contig level and may not
            necessarily reflect any known order or orientation between contigs.
            For answers to your questions regarding this assembly or project,
            or any other GSC genome project, please visit our Genome Groups web
            page (http://genome.wustl.edu/genome_group_index.cgi) and email the
            designated contact person.
            Annotation was added to the contigs in May 2008.
            This is a reference genome for the Human Microbiome Project. This
            project is co-owned with the Human Microbiome Project DACC.
            Product names were updated in August 2012.
            Clostridium sporogenes (GenBank Accession Number for 16S rDNA gene:
            DQ911258*) is a member of the Firmicutes division of the domain
            bacteria and has been isolated from human feces. The sequenced
            strain was obtained from ATCC (ATCC 15579).
            We have collected 8.9X coverage in plasmid end reads and 454 reads.
            We have performed one round of automated sequence
            improvement(pre-finishing), along with manual improvement that
            includes breaking apart any mis-assembly, and making manual joins
            where possible. Manual edits also are made where the consensus
            appears to be incorrect. All low quality data on the ends of
            contigs is removed. Contigs are ordered and oriented where
            possible.
            Sequencing/Assembly: The genomic DNA was purified from liquid
            culture derived from a single bacterial colony. A hybrid sequencing
            strategy that utilized reads from both 454 GS-20 and ABI 3730xl
            sequencers was devised and implemented to generate the draft genome
            sequences. 454 reads were assembled using Newbler (454 Life
            Sciences) into 454 de novo contigs.These de novo contigs were
            converted in silico to 800 base paired reads ('superreads') with
            400 base overlaps with neighboring superreads. Finally, PCAP
            (Huang, et al, Genome Research, 13:2164, (2003)) was used to
            assemble the super-reads and the conventional 3730xl capillary
            reads.
            This sequenced strain is part of a comprehensive, sequence-based
            survey of members of the normal human gutmicrobiota.  A joint
            effort of the WU-GSC and the Center for Genome Sciences at
            Washington University School of Medicine, the purpose of this
            survey is to provide the general scientific community with a broad
            view of the gene content of 100 representativesof the major
            divisions represented in the intestine's microbial community. This
            information should provide a frame of reference for analyzing
            metagenomic studies of the human gut microbiome. Further details of
            this effort are described in a white paper entitled 'Extending Our
            View of Self: the Human Gut Microbiome Initiative (HGMI)'
            (http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMIS
            eq.pdf). These studies are supported by National Human Genome
            Research Institute.
            For answers to your questions regarding this assembly or project,
            or any other GSC genome project, please visit our Genome Groups web
            page (http://genome.wustl.edu/genome_group_index.cgi) and email the
            designated contact person.
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline
            set; GeneMarkS+
            repeat_region
            ##antiSMASH-Data-START##
            Version      :: 5.0.0alpha
            Run date     :: 2018-12-14 14:15:44
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1232631
            Orig. end    :: 1273319
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     cluster         1..40688
                     /aStool="rule-based-clusters"
                     /cluster_number="4"
                     /contig_edge="False"
                     /core_location="[1242631:1263319]"
                     /cutoff="20000"
                     /detection_rule="(minimum(2, [GRDB, Gly_reductase,
                     Pro_racemase]) and Pro_racemase and Gly_reductase)"
                     /neighbourhood="10000"
                     /parent_cluster_number="4"
                     /product="proline2aminovalerate"
                     /tool="antismash"
     cluster_core    10001..30688
                     /aStool="rule-based-clusters"
                     /cluster_number="4"
                     /cutoff="20000"
                     /detection_rule="(minimum(2, [GRDB, Gly_reductase,
                     Pro_racemase]) and Pro_racemase and Gly_reductase)"
                     /neighbourhood="10000"
                     /parent_cluster_number="4"
                     /product="proline2aminovalerate"
     supercluster    1..40688
                     /child_cluster="4"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [GRDB, Gly_reductase,
                     Pro_racemase]) and Pro_racemase and Gly_reductase)"
                     /kind="single"
                     /product="proline2aminovalerate"
                     /supercluster_number="4"
                     /tool="antismash"
     region          1..40688
                     /contig_edge="False"
                     /product="proline2aminovalerate"
                     /rules="(minimum(2, [GRDB, Gly_reductase, Pro_racemase])
                     and Pro_racemase and Gly_reductase)"
                     /supercluster_numbers="4"
                     /tool="antismash"
     gene            163..1917
                     /locus_tag="CLOSPO_RS05930"
                     /old_locus_tag="CLOSPO_02511"
     CDS             163..1917
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254984.1"
                     /locus_tag="CLOSPO_RS05930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02511"
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="WP_003484748.1"
                     /transl_table=11
                     /translation="MNSSIELIYTVKNVMKTDFIKVLKNEAISSAFNRMAKLYKDEVLI
                     VDEDDNIIGIFTKNDLYKLENEGKRFSDNLENYIKRDVITISEEKSIISARNIMVKNKI
                     ERLPIVHNRKIIGIVHLDDLNNELYTNVEELYALQDRILENMHEAVCITNNKGVVIYWN
                     KSSEDLYGVKRQEIIGKYLGSFFPNALILKVLKKPRKITNVNNEPSPGKTVILSAVPIF
                     NSKNKLIAVASTDRDITEVISLSKELMQEKKKVEFFESAYKKEIASNYSFSSIIGKSQK
                     IIENIAIAKKVAPTSASVLITGESGTGKEVFAKAIHKASGRTGNFVAINCSAIPENLFE
                     SELFGYVGGTFTGSLKEGKIGKFEFANNGTLFLDEIGDMPLSMQAKLLRVLQDGVVYRI
                     GSQKGTKVNCRILAATNRDLQFMIKENTFREDLFYRFAVVHIELPPLRERRDDIKDFID
                     LFINQISEKEGIKINTIDKEVYDILCSYKWEGNIRQLKNVVERMVVLSTNGEVTISSVP
                     NHIVQDVEEIEGESHHRYDLNEVVKNTEKKIIKEVMEIAKGNKKKAAEILNIKRSTLYY
                     KLNQYDLI"
     gene            2092..3402
                     /locus_tag="CLOSPO_RS05935"
                     /old_locus_tag="CLOSPO_02512"
     CDS             2092..3402
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254983.1"
                     /locus_tag="CLOSPO_RS05935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02512"
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="WP_042384672.1"
                     /transl_table=11
                     /translation="MSNLYKFYLKMHIGAPSVPCVKEGEFVERGQVIAEPNGLGARIHS
                     SVSGKVFKITDKEVLVEASENQSEDFVKIKECDSILDTVYEAGIVGAGGAGFPTHVKLK
                     ANIPEGYIIANCAECEPTLHHNVYLAENNPELIIKGIKYAMKATNAKKAYIGIKGKRKK
                     AIEVLKEHLKNEQNIQIKEVIDIYPSGEERALIHFIFGEWLAPTQIPIEANCVVLNVET
                     LANITRAVEERKPVIDKDITLMGKLKKGIGPHVFLQEHIGKSMKDMIETCGGIDGQYGE
                     IIIGGPHTGLPEDIEKSVITKVSGGATVTMELPEYKGPVGLLVCACAGDEDRLKDIASK
                     MKSEVVAITKCKNVVEVRGTYKCKTPGKCPGQAGAVMYLKSKGAKRIIIANCSDCSNTV
                     MGIAPKMKLPVYHQTDHVLRTVDYKLTRRLPKEKLHK"
     gene            3434..3862
                     /locus_tag="CLOSPO_RS05940"
                     /old_locus_tag="CLOSPO_02513"
     CDS             3434..3862
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388185.1"
                     /locus_tag="CLOSPO_RS05940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02513"
                     /product="hypothetical protein"
                     /protein_id="WP_003484752.1"
                     /transl_table=11
                     /translation="MSMSAEHAEELKNEPAVVCCRTEEGTILSADNLEDPDIFPDMIDS
                     GLLTMPEDHLKVGQVIGAKLLKTIDSLTPLTPAIVEGYKEIGGEEDKKEEAPKAEEAVE
                     VLEAPEVYEEGCMAASVEGGVLKIKIEEGRGIDIELPL"
     gene            3935..>3994
                     /locus_tag="CLOSPO_RS19185"
                     /pseudo=""
     CDS             3935..>3994
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254982.1"
                     /locus_tag="CLOSPO_RS19185"
                     /note="incomplete; partial in the middle of a contig;
                     missing stop; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLKYGDKNDGKKKYCRNASN"
     gene            4425..4904
                     /locus_tag="CLOSPO_RS05950"
                     /old_locus_tag="CLOSPO_02515"
     CDS             4425..4904
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254981.1"
                     /locus_tag="CLOSPO_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02515"
                     /product="hypothetical protein"
                     /protein_id="WP_003484757.1"
                     /transl_table=11
                     /translation="MTTFILYGTVIVLYLVSFFKDKSKTKKALLMGIKSFENIMPQFLT
                     IIFIVGIILTILLPESISSIIGEKSGFIGVIIAAIIGSVTLIPTFVAFPTAALLLKNGA
                     GYTQITALISAFMFVGIVTFSMEAKFIGKKATFIRNIVYFFYSILSAFIVGILMR"
     gene            4909..5436
                     /locus_tag="CLOSPO_RS05955"
                     /old_locus_tag="CLOSPO_02516"
     CDS             4909..5436
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254980.1"
                     /locus_tag="CLOSPO_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02516"
                     /product="permease"
                     /protein_id="WP_003484759.1"
                     /transl_table=11
                     /translation="MKWLKRYVFFIIILMLTLIITLIDFNKGQNISLIALDSFKQMLAV
                     LPPIMLLLGLLDTWVPRQTMIKYMGDNSGILGIVLAILLGALAAGPVYAAFPVTAVFIK
                     KGTKFSNIMIFMGAWCATKIPTFLFELSALGYKYTFSRLLVNLPSIIILAYLIEGLLSK
                     NDLEKIYNKFKE"
     gene            6029..7333
                     /locus_tag="CLOSPO_RS05965"
                     /old_locus_tag="CLOSPO_02517"
     CDS             6029..7333
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388178.1"
                     /locus_tag="CLOSPO_RS05965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02517"
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="WP_003484761.1"
                     /transl_table=11
                     /translation="MEKMYKFPLKMHVGAPDVPCVKEGQEVKRGECIAEPNGLGAKIHT
                     SVSGIVEKITDAEIIIKADENGSKDFVKIKECDNILEIIAEAGIVGAGGAGFPTHIKLK
                     ADIPDGYVIANCVECEPALHHNIAFIEKEPDTIIKGLRYAMKATNAPKGYIAIKGKHEK
                     AIKILKDHLKGASDIEVKELQDIYPMGEERAIIHAILGKWLEPTQLPLEAKCVVINGET
                     LANITRAVEDRKPVIDKDITIIGKLKTGNKPNVLFDVAVGTPIHDLIEECGGIDGEFGE
                     VVIGGPYTGKAGDIKESVVTKMSGGAIVTIQLPEYKGPLGLLVCACGANEERLRDIASK
                     MKAEVVGVTKCKNVEEIRGANKCKTPGDCPGQVAGIMKLKKDGAKRILISNCSDCSNTV
                     MCCAPNLGIPVYHHTDHVFRTIDHTLTRRLPIDKK"
     gene            7373..8035
                     /locus_tag="CLOSPO_RS05970"
                     /old_locus_tag="CLOSPO_02518"
     CDS             7373..8035
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388177.1"
                     /locus_tag="CLOSPO_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02518"
                     /product="hypothetical protein"
                     /protein_id="WP_003484763.1"
                     /transl_table=11
                     /translation="MSMSAEHAEELKNEPAVVCCRTEEGTILSADNLEDPNIFPDMVDS
                     GLLNIPGDCLKVGEVIGAKLLKTIDSLTPLTKDIVEGAKSLDGDVRSKSEIQIESPEEK
                     AILKNNLKAGDVIKVEDLENPMHFEKLQDSLLIKSDEKVLTRGEVVGAKLTEDAPAISG
                     VTASMLEGFEEKALEITQDSKEVDFNSVIPLNGNRGFLRLKMEEGTGIYIEIPFTQV"
     gene            8663..9781
                     /locus_tag="CLOSPO_RS05975"
                     /old_locus_tag="CLOSPO_02519"
     CDS             8663..9781
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254978.1"
                     /locus_tag="CLOSPO_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02519"
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="WP_042384677.1"
                     /transl_table=11
                     /translation="MEKLYKFSLKMHVGAPDVSCVKEGQKVKRGECIAEPNGLGAKIHT
                     SVSGVVEKITDKEIIIKADENQTKEFVKIKKCDNLVDTVFEAGIVGAGGAGFPTHIKLK
                     ADNKDGYIIANCVECEPALHHNMKVIEETPELIINGIKYAMKATNSKKGYIAIKAKHEK
                     AVRVLEEALKNISNIELKLLKDLYPMGEERAIINAIFDKWLDVTELPIAAKCIVMNAET
                     LANITRAVEEGKPVIDKDITVIGKLKSGNKPNVFLQVPVGTPVKDLIEKSGGIDGEYGE
                     LVIGGPYTGKAGDIEKDAVTKISGGAIVTIPLPEYNGPLGLLVCACGANEERLRDVATK
                     MNAEIAGVVDCKNIEYPKGKGNGPGKCKTPGE"
     gene            9803..9979
                     /locus_tag="CLOSPO_RS05980"
                     /old_locus_tag="CLOSPO_02520"
     CDS             9803..9979
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388175.1"
                     /locus_tag="CLOSPO_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02520"
                     /product="hypothetical protein"
                     /protein_id="WP_003484767.1"
                     /transl_table=11
                     /translation="MQLKKDGAKRILISNCNDCSNTVMQIAPKAKIPVYHHTDHIFRTI
                     DYTLTRRLKEEEK"
     gene            10001..12109
                     /locus_tag="CLOSPO_RS05985"
                     /old_locus_tag="CLOSPO_02521"
     CDS             10001..12109
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Gly_reductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388174.1"
                     /locus_tag="CLOSPO_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02521"
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="WP_042384679.1"
                     /sec_met_domain="Gly_reductase (E-value: 4e-27, bitscore:
                     91.8, seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMTAEHAEELKNEHAVVCCRTEEGTILSADNLEDPEIFPDMVDS
                     GLLTIPDNCLKVGEVIGAKLLKTVDSLTPLTSDIVEGAKKIDEEDKEGSTTEEELTEGN
                     EKAVLKYNLKTGDTIKASDLENPMHFPKLVDSLLISLDERVLTREEVVGATLSVDTPAL
                     TPVTPDILEGFEEEVNMSVDSNATVSGGTLRIKIAEGRGIDIEVPLNGNVGAGKSAKVP
                     TVKAEKGEVVAAPAVEGNKEVKLEEKVIRSLTRKHYKIDKVEFGPETKIEGTTLYIREG
                     VSEDAKKVSPLVKKVEIDIITPDKYNTYSETIMDVQPIATKEGDNKLGTGATRVLDGVI
                     VMVTGTDENGVQIGEFGSSEGILEENIMFNRPGSPDKGEIFIKTQVTIKEKTNMERPGP
                     MAAHKATDFITQEIREAMKALEDESLVVNTETFEQKRRPGKKKVVVVKEIMGQGAMHDN
                     LILPVEPVGYLGGKPNVDLGNVPVMLSPLEVLDGGIHALTCIGPASKECSRHYWREPLV
                     MECMKDEELDLCGVIFVGSPQINSEKFYVSERMGMMVEALDVDGAFVTTEGFGNNHIDF
                     ASHVEQIGMRGIPCVAFSFCAVQGALVVGNKYMKYMIDNNKSEGGIENEVLECNTLCPE
                     DAIRGVEMLKAAMVGEDVKKPERAWNANVKENNLELIEKAENVKIERVLNETSIPMSEK
                     RKEKYSTK"
     gene            12118..12393
                     /locus_tag="CLOSPO_RS05990"
                     /old_locus_tag="CLOSPO_02522"
     CDS             12118..12393
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254975.1"
                     /locus_tag="CLOSPO_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02522"
                     /product="hypothetical protein"
                     /protein_id="WP_003484771.1"
                     /transl_table=11
                     /translation="MNLKYGDKIIEMEGVIVEVSDGAVAIDFKGRLGYLKIPRRMIISD
                     YELKVGQEIGLNMSFVEVLSDKINEKYVSNLEIQKRRGVKPEDRWK"
     gene            12471..13196
                     /locus_tag="CLOSPO_RS19190"
     CDS             12471..13196
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: GRDB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /locus_tag="CLOSPO_RS19190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="WP_077272288.1"
                     /sec_met_domain="GRDB (E-value: 6.7e-15, bitscore: 52.4,
                     seeds: 64, tool: rule-based-clusters)"
                     /transl_except=(pos:1245552..1245554,aa:Sec)
                     /transl_table=11
                     /translation="MSLTITKGLQSEIFVPITPDPVWAPVTKELKDMTVAIATAAGVHL
                     KKDKRFNLAGDFTYRLIPGDAKTSDMMVSHGGYDNSDVNKDINAMFPIDRLRELVDAGF
                     IKAVAPTHIGFMGGGGNQQKFREETGPEVAKILKEEGVDAVLMTAGUGTCHRSAVLVQR
                     AIEKEGIPTIIIAALPPVVRQTGTPRAVAPRVPMGANAGEPNNVEMQTAIVKDTLEQLI
                     KIPSAGKIVPLPYEYIAKV"
     gene            13537..14313
                     /locus_tag="CLOSPO_RS06005"
                     /old_locus_tag="CLOSPO_02525"
     CDS             13537..14313
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Gly_reductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388171.1"
                     /locus_tag="CLOSPO_RS06005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02525"
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="WP_042384680.1"
                     /sec_met_domain="Gly_reductase (E-value: 4.1e-07, bitscore:
                     25.9, seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQEIILRRLVIKAFHITKVELSDRTYIEDKVLYIRKDILDGILQ
                     HEDMEGQELIEKIDLNIINPKERHKFVNSIMDFSPVATKVLGALGEGITHVLTGVQVML
                     TGAEECGIQVAEFGSSEGILDEQVVFGRRGTPAEDDIIVHINVTLKNGQATNRPGPMAA
                     HRVCDIIIQEIRNYLKKINGRYCDEKHEYFDKIRPGKKKVVIVKQVAGQGCMYDTGLFA
                     KEPGGHIGCKSIIDMGNMPVVVSPNEYRDGILRAMN"
     gene            14327..14797
                     /locus_tag="CLOSPO_RS06010"
                     /old_locus_tag="CLOSPO_02526"
     CDS             14327..14797
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Gly_reductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254972.1"
                     /locus_tag="CLOSPO_RS06010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02526"
                     /product="hypothetical protein"
                     /protein_id="WP_003484779.1"
                     /sec_met_domain="Gly_reductase (E-value: 1.3e-10, bitscore:
                     37.4, seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIGPSTKETTLHHFRDPLVEIVSNDGDIDLLGIIVAGTPQANEE
                     KVFTGQRIGAWAEAMRVDGAIVSIDGWGNSNIDFASALEAIGKRDIPVVGMSFVGTQAQ
                     FVVTNEFMDTVVDFNKSEAGIETEVVGENNVMPIDAKKALAFLKLKMKRKQN"
     gene            14811..15818
                     /locus_tag="CLOSPO_RS06015"
                     /old_locus_tag="CLOSPO_02527"
     CDS             14811..15818
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Pro_racemase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254971.1"
                     /locus_tag="CLOSPO_RS06015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02527"
                     /product="proline racemase"
                     /protein_id="WP_003393245.1"
                     /sec_met_domain="Pro_racemase (E-value: 7.4e-130, bitscore:
                     429.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAIKTIQTIESHTMGEPTRIVIGGLPKVPGKTMAEKMEYLEENN
                     DSLRTMLMSEPRGHNDMFGAIYTEPADETADLGIIFMDGGGYLNMCGHGSIGAATCAVE
                     MGIVKVEEPYTNIKLEAPAGMINARVKVEDGKAKETSIVNVPAFLYKKDVEIDVPDYGK
                     LTLDISFGGSFFAMVDAEKVGIDISPANSQKLNDLGMKIVHAVNEQVEIKHPVLEHIKT
                     VDLCEFYGPAKSEDADVQNVVVFGQGQVDRSPCGTGTSAKMALLYAQGKMKVGEEIVNE
                     SIICTKFKGKILEETKVGEYDGIIPEITGSAYVTGFSQFLVDEEDPVKYGFVLK"
     gene            16337..17206
                     /locus_tag="CLOSPO_RS06030"
                     /old_locus_tag="CLOSPO_02528"
     CDS             16337..17206
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003484781.1"
                     /locus_tag="CLOSPO_RS06030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02528"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_003484781.1"
                     /transl_table=11
                     /translation="MIVKIVFGILLILTLYFAFIFFKDFVKNSKEGNLEEISFWKAGAV
                     GFIANFFDTLGIGSFAPLTAMLRFLKLTEDRVLPGTLNVSCTIPVVTEALIFITVIKVD
                     PVTLFAMLISATVGAVVGAGIVSKFDEKKVQLGMGIALMIVACLMLASQLKLMPVGGTA
                     IGLTGGKLVIAVIANFFLGALMTLGIGLYAPCMALVFALGMSPKVAFPIMMGSCAYLMP
                     AASAKFVKEGAYNRKASMAITIFGVIAVLIAAYIVKELPLNILTWLVIVVIIYTSTTMF
                     KAYSKGKI"
     gene            complement(17355..18800)
                     /locus_tag="CLOSPO_RS06035"
                     /old_locus_tag="CLOSPO_02529"
     CDS             complement(17355..18800)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254969.1"
                     /locus_tag="CLOSPO_RS06035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02529"
                     /product="amino acid permease"
                     /protein_id="WP_003484783.1"
                     /transl_table=11
                     /translation="MKKSLTFKDMVLMTMTAILGLRWVAVSAKYGASCAVLWGIAALLF
                     FIPSALVAAELGGKYPEQGGLSVWVTKAYGEKMGFLVSWLNWVSKLFFYPGFVTYAAVT
                     FAYVIDPSLANNKLYNLFMVLGIFWFITIWSFRGTGNSKIFAVIGGLVGSVLPALLIII
                     LGYASAFVLKRPLATPYTLQGMIPDFSNIANLALLSSVMFGLTGAEVTAAFAGEVEDAK
                     KTIPKAIIFCAIFITILYILCSSAITFVVSPEKIGAANGLIEAFRLITEQFGIGQWFLT
                     LMAILMTIEALGGVSLYIMSPITMLFETSKNGVLPPFLTKTNKNGVPINALLVQGIGIS
                     IVIIVTTLLPTVNAIYSILIIMTAITGLIPYLLMFASYIRLKKMEKLQAKGESTEEFYE
                     ISKSKQFSTFVSIVGLISVIFGIVTSFFPPSDYTTTGQIAFFELLSIGGPILLSWIGWR
                     MFSKYEQRRDKGEIQSKNNFASK"
     gene            18940..19185
                     /locus_tag="CLOSPO_RS06040"
                     /pseudo=""
     CDS             18940..19185
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004451062.1"
                     /locus_tag="CLOSPO_RS06040"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKKYFIS"
     gene            19362..20438
                     /locus_tag="CLOSPO_RS06045"
                     /old_locus_tag="CLOSPO_02530"
     CDS             19362..20438
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001255679.1"
                     /locus_tag="CLOSPO_RS06045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02530"
                     /product="hypothetical protein"
                     /protein_id="WP_003483448.1"
                     /transl_table=11
                     /translation="MSFQLPKFTPPDFTQDVLVKAPDVKIGEVEKDGVAPQGFHITSVL
                     PEYFKVKGEWVLPTQTSLDCAAIVKDDNTVEVVEFRSLKVGDKVILGKSVDGSEGIYKY
                     AEGFDNIPKVGFGRTVESSFSKDYKELYEILKHEKENNGHIVWVLGPAVVFDYDTRVAL
                     SELAEKGFVNALMAGNAMATHDLEGGLLGTALGQNIYTQESVPMGHYNHLDLINEARRA
                     GSIEALLSEGNVKDGFIKACIEHNIPIVLAGSIRDDGPLPPVYHNVTSGLDAMKEQAQK
                     ATVIICLATVLHSVATANLASSYKVVDGKVRPVYVYSIDIAEYAVNQVATAREHVGVKT
                     IVTNVQDFVVNVQKNVLK"
     gene            20507..21592
                     /locus_tag="CLOSPO_RS06050"
                     /old_locus_tag="CLOSPO_02531"
     CDS             20507..21592
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254967.1"
                     /locus_tag="CLOSPO_RS06050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02531"
                     /product="hypothetical protein"
                     /protein_id="WP_003484786.1"
                     /transl_table=11
                     /translation="MSFELPKFTPPDFTQDFLVKAPDCKTEEVVIEGVAPRHYHALSIY
                     PEYFKIKGKWVIANESRMDTVAIVTPEDDIEVVEFRNLKLGDKVVVGRTEDASEGIYMY
                     AGGFVAKDGNSDTFAFRSGRSRETAFSKDYDDLYEIMKYEKEHNGKITWVLGPSIALDD
                     ESRAAFASLVENGYVNAILSGNTLATYDLEKGMFGTVLGQETFEAEKNAHYNYMEAINE
                     ARRAGSLEELMASGKVKDGILKACVEKDVPVVLAGTIRDRFTLPNVYDNAYEAQDAMRK
                     HTRKSTMLICLSTVLHTIASGNMTPSYTVRDGVVRPVYIYSIDIQEFSVNKLSDRGTLE
                     VKTLVTNAQDFITNIAKALVK"
     gene            22073..24091
                     /locus_tag="CLOSPO_RS06055"
                     /old_locus_tag="CLOSPO_02532"
     CDS             22073..24091
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388161.1"
                     /locus_tag="CLOSPO_RS06055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02532"
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_080333547.1"
                     /transl_table=11
                     /translation="MKKLSFKMKLLITILPVVIIGMSILSFITFYEFRKNIENELVNNK
                     LEEGKKLTESINNWLEGKLLEVRSAANTPTAKLIETDVAAVDNFNAERIKFLEKNYPGE
                     YDNAAATLFNNDGKSRAQYSNGKFVNGDVSEKTWYKDLMSGVPYNISNPVVSKGTGKTL
                     VVIGVPIKNKSEKTIGTMISAVNLLHIKEKVKEFKFGEKGYSLLIGKDGTILEHPDKSL
                     VMQKKISEIKDENIQSLGKEMMKNESGVFRFGSGDNKSIVFYNKVPLSGWNVASVVSEK
                     ELFAPLNKLMLTLILITIVIVFIVATVIVFVAKQITLPLTKLSDFAEEIAEGNLTNKLE
                     VHGQDEISKVTKALNNTVSKLKKMIGDISSSANDVMVISNGLALSTSESLKGNEEVSRS
                     MQEIATGAVSQAEGASKASIVTRELVEDINEISKKCNYMIDIVEKSTNRSTKVSQGVQH
                     TVDSIKNIATTNKHNVEEIQNLLNQSKEIGQIVDVISDISEQTNLLSLNAAIEAARAGA
                     QGRGFAVVADEVRKLAEQSSNSSKRIVELINGIQKQIEIISNKMNSGTSEVMHGVKMAT
                     LIGNDFEEIEKVFNEVNNIVLEVSESTNTMEKKVNVTADIINNVASVTEENSSATEEVT
                     ASNEEQIAFMHQIVDSTYTLEELVKKLKDTVYKFKLS"
     gene            24403..25299
                     /locus_tag="CLOSPO_RS06060"
                     /old_locus_tag="CLOSPO_02533"
     CDS             24403..25299
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254965.1"
                     /locus_tag="CLOSPO_RS06060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02533"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_042384686.1"
                     /transl_table=11
                     /translation="MITKLLLSVLLVLTSYFLFFFLKDYFKSLKKGNLEDNNFFIVGII
                     GLVVNFFDTLGIGSFAPLTSMLKFFKQTEDKVIPGTLNVGCTVPMILQAFIFMTGIKVE
                     PVTLVSMIIAAMIGSLFGAEIVSKLDEKKVQFCMGVSLLIVALIILAGQLNLMPAGGND
                     IGLHGTKLIIAIVGNFILGILMTVGIGLYAPCMALVCVLGMNPKVAFPIMMGSCAFLLP
                     MSSTKFVKNNAYDKKASISISIFGVVGVLIAAFIVKELPVRALTWMVVCVIMYTSITMF
                     KAYYSKKESYETREELA"
     gene            26196..27314
                     /locus_tag="CLOSPO_RS06065"
                     /old_locus_tag="CLOSPO_02534"
     CDS             26196..27314
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254964.1"
                     /locus_tag="CLOSPO_RS06065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02534"
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="WP_003484795.1"
                     /transl_table=11
                     /translation="MEKLFSFPLRMHVGAPDAPCVKEGQKVKRGECIAEPNGLGAKIHT
                     SVSGIVEKVTDKEIIIKADEAQTTEFVKIKKCDNLVDTVFEAGIVGAGGAGFPTHIKLK
                     SDNKDGYIIANCVECEPALHHNIKVIEETPELIINGVRYAMKATNSAKGYIAIKAKHPE
                     AIASLEKALKGATDVEVKPLADLYPMGEERAIINAIFDKWLDVTQLPIEAKCIVMNAET
                     LANITRAVEEGKPVIDKDITVIGKLKSGNKPNIFLQVPVGTPVKDLIEKSGGIDGEYGE
                     LVIGGPYTGKAGDIEKDAVTKISGGAIVTIPLPEYNGPLGLLVCACGANEERLKDVATK
                     MNAKIAGVVDCKNIEYPKGKGNGPGKCKTPGE"
     gene            27336..27506
                     /locus_tag="CLOSPO_RS06070"
                     /old_locus_tag="CLOSPO_02535"
     CDS             27336..27506
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254963.1"
                     /locus_tag="CLOSPO_RS06070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02535"
                     /product="hypothetical protein"
                     /protein_id="WP_003362611.1"
                     /transl_table=11
                     /translation="MQLKKDGAERILISNCSDCSNTVMQIAPKAKVPVYHHTDHIFRTI
                     DYTLTRRLPQE"
     gene            27541..29655
                     /locus_tag="CLOSPO_RS06075"
                     /old_locus_tag="CLOSPO_02536"
     CDS             27541..29655
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: Gly_reductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388157.1"
                     /locus_tag="CLOSPO_RS06075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02536"
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="WP_042384691.1"
                     /sec_met_domain="Gly_reductase (E-value: 1.8e-21, bitscore:
                     73.2, seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMTPEHAEALKNESAVVCCRAEEGTVLTADNLEDPEIFPDMVDS
                     GLLTIPADCLKVGEVIGAKLLKTVDSLTPLTPDIIEGAKTIGDSEDKAEEISEELTEED
                     EKAVLKYNLKAGDTIKASDLENPMHFPKLVDSLLLTLDERVLTRKEVVGATLSVDMPAL
                     TPVTPDILEGFEEEVNMSADTQATISGGTLRIRIAEGKGIDIEVPLNGNVGAGKSVAVP
                     AVKAEKGTVTAAPVAVEAKKEVKLEEKVVRSVTRKYYKIDKVELAKETKIEGTTLYIRE
                     NICEDAFNVDQLVKDIKLEIITPDKYNTYSETIMDVQPIATKEGSDAKLGEGVTRVIDG
                     AIIMVTGIDEDGVQVGEFGSSEGILEENIMWGRPGAPNKGEIFIKTQVTIKRGTGMERP
                     GPLAAHKATDFITQEIREALKAVEDDSLVVNTETFEQVRRPGKKKVVVVKEIMGQGAMH
                     DNLILPLEPVGVIGAKPNVDLGNVPVMLAPTEVLDGGIHALTCIGPASKECSRHYWREP
                     LVMECMRDEEVDLAGVIFVGSPQINSEKFYVSERLGMMVEAMDVDGAFVTTEGFGNNHI
                     DFASHVEQIGMRGVPCVAFSFCAVQGALVVGNKHMKYMVDNNKSEGGIENEVLSCNTLC
                     PEDAIRGLAMIKAAMSGEEVKKPERAWNANVKENNIEMIEKTTGNKIDRVLNETSIPMS
                     EKRKEKYATK"
     gene            29664..29939
                     /locus_tag="CLOSPO_RS06080"
                     /old_locus_tag="CLOSPO_02537"
     CDS             29664..29939
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254961.1"
                     /locus_tag="CLOSPO_RS06080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02537"
                     /product="hypothetical protein"
                     /protein_id="WP_003393224.1"
                     /transl_table=11
                     /translation="MDLKYGDKILEMQGVIVDVSDGAVAIDFKGRLGYLKVPRRMIISD
                     YELKVGQEIGLNMSFVEVLSDEINEKYVSNLEIQKRRGLNPDERHK"
     gene            29969..30688
                     /locus_tag="CLOSPO_RS19195"
     CDS             29969..30688
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proline2aminovalerate: GRDB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986810.1"
                     /locus_tag="CLOSPO_RS19195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="WP_080333546.1"
                     /sec_met_domain="GRDB (E-value: 1.9e-14, bitscore: 50.9,
                     seeds: 64, tool: rule-based-clusters)"
                     /transl_except=(pos:1263044..1263046,aa:Sec)
                     /transl_table=11
                     /translation="MNIVKGLQSEIFVPITPNPVWAPVTMELKDMTVALATAAGVHLKS
                     DKRFNLAGDFTYRLVPGDAKTSDMMVSHGGYDNGDVNKDINAMFPIDRLRELVDAGFIK
                     AVAKTHIGFMGGGGNQQKFREETGPEVAKILKEEGVDAVLMTAGUGTCHRSAVIVQRAI
                     EEIGIPTIIIAALPPVVKQSGTPRAVAPRVPMGANAGEPNNVEMQTAIVKETLEQLIKI
                     PSAGKVVPLPYEYIAKV"
     gene            31055..31933
                     /locus_tag="CLOSPO_RS06095"
                     /old_locus_tag="CLOSPO_02540"
     CDS             31055..31933
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254959.1"
                     /locus_tag="CLOSPO_RS06095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02540"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_003484803.1"
                     /transl_table=11
                     /translation="MVKIVLGLLIILTVFFAVAFFKDYIKATKEGNIEKTNFFALGTVG
                     FITNFFDTLGIGSFAPTTALLKNFKLTQDRTLPGTLNVACTVPVAVEAILFINGIEVEP
                     VTLFSLLIAATAGAVVGAGVVSKLDEKKVQFGMGVALVIVALVMLAGQLNLMPAGGDAT
                     GLHGVKLIVAIIGNFILGALMTLGIGLYAPCMALVYALGMSPKVAFPIMMGSCAFLMPA
                     ASLKFVKEGAYDRKASMAITIFGLVGVFIAYYLVKSLPLDILKWLIIVVILYTAVMMFN
                     SSSKAKKAVKA"
     gene            32267..33265
                     /locus_tag="CLOSPO_RS06100"
                     /old_locus_tag="CLOSPO_02541"
     CDS             32267..33265
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388153.1"
                     /locus_tag="CLOSPO_RS06100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02541"
                     /product="phosphate acetyltransferase"
                     /protein_id="WP_003484805.1"
                     /transl_table=11
                     /translation="MDLMKSLWEKAKSDKKKIVLAEGEEERNIEGCSKILKNELAHMIL
                     IGNEEKINETAKKLNVSIDGAEIIDPQTSEKVSTYTKEFYELRKHKGVTMEKAEQIVKD
                     PIYFATMMVKMKDADGLVSGAIHTTGDLLRPGLQIVKTAKGASVVSSTFIMEVPNCEYG
                     KNGMLLFADCAVNPNPTADELASIAISTAETAKALCDMEPKVAMLSFSSKGSAKHDLVD
                     KVAEATKIAKEKRPDLDIDGELQLDAAIVQKVADLKAPNSTVAGKANVLVFPDLQAGNI
                     GYKLVQRFANASAIGPICQGFAKPINDLSRGCSSDDIVNVVAVTAVQAQNM"
     gene            33404..34597
                     /locus_tag="CLOSPO_RS06105"
                     /old_locus_tag="CLOSPO_02542"
     CDS             33404..34597
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254957.1"
                     /locus_tag="CLOSPO_RS06105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02542"
                     /product="acetate kinase"
                     /protein_id="WP_042384694.1"
                     /transl_table=11
                     /translation="MKILVVNCGSSSLKYQLIDMTSEEALAKGLVERIGIEGSILTQKV
                     NGEKYIIEEPMKDHKKAIELVLKALVDKEHGVISDMSEIAAVGHRVVHGGEKYASSVLI
                     DDEVMKALEDCVKLAPLHNPPNIIGINACRELMPKTPMVAVFDTAFHQTLPDYAYMYPL
                     PYELYEQNGIRKYGFHGTSHRYVSSVASEMMGKDLKDIKVITCHLGNGASLCAVKEGKS
                     VETSMGFTPLAGLAMGTRCGDIDPAILLFMERELKMSPDEVDNVINKKSGVLGISGVSS
                     DFRDIEGAAEEGNKRAKLALDVYHYTVRQTIGAYTAVLNGVDAIVFTAGLGENSAASRE
                     EILNGLEYLGIKIDAEKNKQRGKQIEISTEDSKVKVFVIPTDEELMIARDTKEITAK"
     gene            34715..35215
                     /locus_tag="CLOSPO_RS06110"
                     /old_locus_tag="CLOSPO_02543"
     CDS             34715..35215
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388151.1"
                     /locus_tag="CLOSPO_RS06110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02543"
                     /product="DNA-binding protein"
                     /protein_id="WP_042384698.1"
                     /transl_table=11
                     /translation="MNLDVSDLIKKIKLSKDVHLKLEDQRKFFDGDEEILYLEAPTLDG
                     VVSISKDILTLDGKLSAEIELSCSRCLQKFKHHVDTEVHESFTNNPQCEDDEIMLLKNE
                     AIDVTEVIENNIIIELPIKRLCKENCKGLCQQCGANLNFSKCKCEKDIDPRLAKLKDFF
                     SAQ"
     gene            35229..35411
                     /locus_tag="CLOSPO_RS06115"
                     /old_locus_tag="CLOSPO_02544"
     CDS             35229..35411
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388150.1"
                     /locus_tag="CLOSPO_RS06115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02544"
                     /product="50S ribosomal protein L32"
                     /protein_id="WP_003362601.1"
                     /transl_table=11
                     /translation="MGNPARKTSKAKRDSRKAQTFKLSLPGIVECPQCHEMKLAHRVCK
                     SCGYYNGKEVVSNDK"
     gene            35502..36509
                     /locus_tag="CLOSPO_RS06120"
                     /old_locus_tag="CLOSPO_02545"
     CDS             35502..36509
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388149.1"
                     /locus_tag="CLOSPO_RS06120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02545"
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="WP_003484808.1"
                     /transl_table=11
                     /translation="MIIAVDGMGGDFAPELVVEGCIQAVKEYEGIHIIITGKEELIKNE
                     LDKREYKGNKIEILNTKEVIGTDEAPVKAIRRKKDSSMVKALELVKEGKAQAVISAGST
                     GALMAGATFVLGRIKGINRVCLAPLLPGAKAPFMIADAGANVDCRPEYLVQFAMMGKVY
                     FESVLGVKNPTVGLVNIGAEEEKGNELTKAAYKLLKDTDFNFIGNIEPRDIPRGETNIA
                     VCDGFIGNTVLKTYEGVASNLFSMLKDEIMSSTRGKIGGALLKPVFKDFKKKFDYTEYG
                     GSPFLGAKGICIKAHGSSDAKAFKNAIRQAKICYDKKIIEEIENNLENLIENNI"
     gene            36587..36820
                     /locus_tag="CLOSPO_RS06125"
                     /old_locus_tag="CLOSPO_02546"
     CDS             36587..36820
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388148.1"
                     /locus_tag="CLOSPO_RS06125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02546"
                     /product="acyl carrier protein"
                     /protein_id="WP_003362599.1"
                     /transl_table=11
                     /translation="MIFEKIKATIAEQLSIDEEEITMESSFIDDLGADSLDIVELIMAL
                     ETEFDLEIPDEDAEKISTVGDVVDYIKSHTEE"
     aSDomain        36602..36805
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CLOSPO_RS06125_ACP.1"
                     /evalue="9.30E-12"
                     /label="CLOSPO_RS06125_ACP.1"
                     /locus_tag="CLOSPO_RS06125"
                     /score="36.8"
                     /tool="antismash"
                     /translation="IKATIAEQLSIDEEEITMESSFIDDLGADSLDIVELIMALETEFD
                     LEIPDEDAEKISTVGDVVDYIKS"
     gene            36945..37649
                     /locus_tag="CLOSPO_RS06130"
                     /old_locus_tag="CLOSPO_02547"
     CDS             36945..37649
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388147.1"
                     /locus_tag="CLOSPO_RS06130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02547"
                     /product="ribonuclease III"
                     /protein_id="WP_042384700.1"
                     /transl_table=11
                     /translation="MKNRQDILKELQYKLKVCFKDEKLLDVALTHSSYANGKKNIKYYE
                     RLEFLGDSVLQLIISEHLYQKYEDKKEGELTRKRAIIVCENSLYEMAKRWDLGFYLQMS
                     KGEELTGGRERVSILADCVESIIAAIYLDKGLDEAREFVMKNFKEIIEKAMRDEIILDY
                     KTTLQEIVQQNNDLTINYELLKQEGPPHRRKFFTNVTIDNEVRGTGIGYSKKEAEQNAA
                     KEALKNLGDNYE"
     gene            37642..38733
                     /locus_tag="CLOSPO_RS06135"
                     /old_locus_tag="CLOSPO_02548"
     CDS             37642..38733
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_14"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388146.1"
                     /locus_tag="CLOSPO_RS06135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02548"
                     /product="radical SAM protein"
                     /protein_id="WP_003484810.1"
                     /sec_met_domain="Radical_SAM (E-value: 7.2e-23, bitscore:
                     79.0, seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_14 (E-value: 6.1e-06, bitscore: 23.6,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKGHYIIPIFVAQEGCPYNCVFCNQHKITGEKDEIIDENYVRET
                     IEAYIKTIDRENSTLEVSFFGGTFTGIPIERQKSLLKVAKEYKDKGQIDCIHMSTRPDY
                     IDREILDNLKKYSADIIELGVQSLDEEVLLKSGRGHSVEEVYRASKLIKEYGFTLGHQI
                     MLGLPGDTFKKDIETVEKSLKMKPDIARIYPALVIKDTPMEYMLRKGTYKPYTLDEAID
                     ITKILYSMYDKEGIKVIRIGLQPTEEINENKDVISGPFHPAFRELVEGKIINEAIFSYV
                     EDSLEESLEIYINNKDISKLYCNRKEFFNEFINKKKVKRFKVIQDETLGRGNIIIKKDE
                     NQEHIFIKEYMRKLSEEGKNLFI"
     gene            38856..38984
                     /locus_tag="CLOSPO_RS06140"
                     /old_locus_tag="CLOSPO_02549"
     CDS             38856..38984
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001388145.1"
                     /locus_tag="CLOSPO_RS06140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02549"
                     /product="hypothetical protein"
                     /protein_id="WP_003362596.1"
                     /transl_table=11
                     /translation="MLFLKGGKIEMKREKREKMTKVLVVVMTIVFIASILPMFFAR"
ORIGIN
        1 aagttataat aacattttat aagtaaaagt taatgaaata attttataat gattaaatat
       61 taattaatta tgttaaaata tatatatact atatgatacc ataaacacag cttgctatac
      121 agaaatctat attatattta tggtacattg gaggaatata agatgaatag ttctatagaa
      181 ttaatttata ctgtaaaaaa tgtaatgaag acagatttta taaaagtact taaaaatgaa
      241 gccatatcat ctgccttcaa tagaatggct aaactttata aagatgaagt tcttatagta
      301 gatgaagatg acaatattat aggtatattt actaaaaatg acctatataa attagaaaat
      361 gaaggtaaaa gatttagtga taacttagaa aattatataa aaagagatgt aataacaatt
      421 tctgaagaga aatcaattat ttctgcaaga aatataatgg ttaaaaataa gatagaaaga
      481 ttacctatag tacataatag aaaaataata ggaatagtac atttagacga tttaaataat
      541 gaattataca caaatgtaga agaattatat gctcttcagg atagaatttt agagaatatg
      601 catgaggcag tatgtataac aaataacaaa ggtgtagtaa tatattggaa taaaagttcg
      661 gaagacctat atggtgtgaa gagacaggaa ataataggaa aatatttagg gtcttttttt
      721 ccaaatgctt taatattaaa agttttgaaa aagcctagaa aaataactaa tgtaaacaat
      781 gagccttctc ctggaaaaac tgttatatta agtgctgtac ctatatttaa tagtaaaaac
      841 aaattgatag cagtggcttc tacagatagg gatataacag aggtaatatc tttatctaaa
      901 gaacttatgc aggaaaaaaa gaaggtggaa ttttttgaaa gtgcctataa aaaagaaata
      961 gcttcaaatt atagtttttc atctattata ggtaaaagtc aaaagataat agaaaacatt
     1021 gctatagcta aaaaagtagc acctacctct gctagcgttc ttattacagg agaaagtgga
     1081 acgggaaaag aggtttttgc aaaagctata cataaagcta gtgggagaac tggaaacttt
     1141 gtagctataa actgtagtgc tatacctgaa aatctttttg aaagtgaatt gtttggttat
     1201 gtgggaggaa cttttacagg ttcattaaaa gaagggaaaa taggtaaatt tgaatttgct
     1261 aacaatggta ctttattttt agatgaaata ggggacatgc cacttagtat gcaagcaaaa
     1321 ctcttaagag ttttgcagga tggtgtggtt tacagaatag gaagtcaaaa gggcacaaag
     1381 gttaattgta gaattttagc tgcaacaaat agggacttac aatttatgat aaaggaaaat
     1441 acctttaggg aagacctatt ttatagattt gcagtagtgc atatagagtt acctccatta
     1501 agagagagaa gagatgatat taaagatttt atagacttat ttataaacca aatatcagaa
     1561 aaggaaggca taaagataaa tacaatagat aaagaggttt atgatatttt atgttcttat
     1621 aaatgggaag ggaatataag acaattgaaa aatgtggtag aaaggatggt agttttatca
     1681 accaatggag aagtaacaat atcttctgtt cctaatcata tagtgcagga tgtagaagaa
     1741 attgaagggg aatctcatca tagatatgat ttaaatgaag tagttaaaaa tacagaaaaa
     1801 aagataataa aggaagtaat ggaaatagct aaagggaata aaaagaaagc agcagaaata
     1861 cttaatataa aaagaagcac tttatattat aaattaaacc aatatgattt aatttaaatt
     1921 aaaaaaattg atttatctgt ataatgttaa aaagtttaaa gtataataag tataataaat
     1981 aaatatggct ttttatataa catattgtta ttgacatatt tctattattt attgttacaa
     2041 tagtcaaaat atgatattat aataaatggg aatttcctaa ggagtgataa aatgtcaaat
     2101 ttatacaagt tttatcttaa aatgcatata ggtgcaccga gtgtgccctg tgttaaagag
     2161 ggggaatttg tagaaagagg gcaggttata gcagagccta atggattggg ggctagaatt
     2221 catagtagcg tatctggtaa ggttttcaag ataacagata aggaagtatt agtagaagct
     2281 tcagaaaacc aaagtgaaga ttttgttaaa atcaaagaat gtgatagcat tctagataca
     2341 gtgtatgaag ctggaatagt aggtgcaggt ggggctggtt tcccaactca tgttaaatta
     2401 aaagcgaata tacctgaggg gtacataata gccaactgtg cagagtgtga accaaccctt
     2461 catcataatg tatatttagc agaaaataat ccagaactta taataaaagg tataaagtat
     2521 gctatgaaag ctactaatgc taaaaaggct tatataggaa taaaaggcaa acgtaaaaaa
     2581 gctatagaag tattaaagga acatttaaag aatgaacaaa atatacaaat aaaggaagtt
     2641 atagatatat atccttccgg agaagaaaga gctttaatac attttatatt tggtgaatgg
     2701 ttagcaccta cacaaatacc tatagaggca aattgtgtag ttttaaatgt agaaacccta
     2761 gcaaatataa caagagcagt agaagagaga aaaccggtta tagataaaga tataaccctt
     2821 atgggaaaat taaaaaaagg tataggtcct catgtatttt tgcaagagca tataggaaag
     2881 tctatgaaag atatgataga aacttgcgga ggtatagatg gacagtatgg agaaattatt
     2941 ataggaggac ctcatactgg gctaccagag gatatagaga aatctgtaat aacaaaggtt
     3001 tctggtggag caacagtaac catggaatta ccagaatata aagggccagt gggactttta
     3061 gtttgtgcct gtgctggaga tgaagatagg ttaaaggata tagccagcaa aatgaaatca
     3121 gaagtagtgg ctataactaa atgcaaaaat gtggtggaag ttaggggcac ttataaatgt
     3181 aaaactccag gtaaatgtcc aggtcaagca ggtgctgtta tgtatttgaa aagtaaaggc
     3241 gcaaaaagga taataatagc taattgtagt gattgttcta atacagttat gggaatagct
     3301 ccaaaaatga agttgcctgt ttatcaccag acagatcatg tacttagaac tgtagattat
     3361 aagttaacaa ggagacttcc aaaagagaag ctccataaat aaaattattt ttaaacttag
     3421 gaggtatatt attatgtcaa tgtcagcaga acatgcagaa gaattaaaaa atgaaccagc
     3481 agtagtttgc tgtagaacag aggaaggaac aatattatct gcagataact tagaggatcc
     3541 agatatattc ccagatatga ttgattctgg attattaact atgccagagg atcatttaaa
     3601 agtaggtcaa gtaataggag caaaattatt aaaaactata gattcattaa caccattaac
     3661 tccagctata gttgaaggat ataaagaaat tggtggagaa gaagacaaga aagaagaagc
     3721 acctaaagct gaagaggctg tagaagtttt agaagcacca gaagtttatg aagaaggttg
     3781 catggcagct tctgtggaag gtggagtact taaaataaaa atagaagaag gaagaggaat
     3841 agatatagaa cttcctctat aaaaattaaa aaacaaagac ttttatgcct ttgtttcagg
     3901 ctgtagacaa ccagatagtc tacagcctat ttttatgcta aaatatggtg ataaaaatga
     3961 tgggaaaaag aaatactgcc gaaatgcatc aaataaaaat gacaagtata gatgaaagaa
     4021 ctgtttttat tgatggtaca catatcaaat ctaacgctaa taaccataaa tgtaaaagtg
     4081 aagctatcga aaaatcagca aaattttatg aagaagcatt aaattaaata tattagaaat
     4141 attaaaatgc ttatgaaaaa tttaacttct cataagcatt ttgttttcaa tctgataagg
     4201 ggctgtcgca ttaaaaaatt tacatacaat atattgtttt gcaaatttaa agttaacaca
     4261 atatattgta ggatttattc ttagtgcgac agccccttat gtttttactg taaaaaaata
     4321 gcatttatga agcggaatta taaattttag agattaagga actaataaaa tggaaattta
     4381 atattaatat agtatagatt taatagtctt tgggaggaag tataatgact acatttatac
     4441 tttatggtac tgtaattgta ctttatttag tttctttttt taaggataaa agcaaaacaa
     4501 aaaaagcatt attaatgggt ataaagtctt ttgaaaatat aatgcctcaa tttttaacga
     4561 ttatatttat agtaggaatc atactgacaa tattattacc agagagtata tcatctatta
     4621 ttggtgagaa atctggattt attggagtga taattgcagc tataataggt tcagtgacat
     4681 taatacctac atttgtagcc tttcccacag cagcattatt attgaaaaat ggtgctggat
     4741 acactcaaat tacagcatta atttctgctt ttatgtttgt tggaatagta actttttcta
     4801 tggaggcaaa atttataggt aaaaaggcaa cctttattag aaatatagtt tacttttttt
     4861 attctatatt aagtgctttt attgtaggaa tacttatgag gtgattttat gaaatggtta
     4921 aaaagatatg ttttttttat aataatatta atgctaactt taataataac gttaattgat
     4981 tttaataaag gacaaaacat aagtttaata gcactggact catttaaaca gatgctggcg
     5041 gtgctgcctc ctataatgtt gttattggga cttttagaca cttgggttcc aagacaaact
     5101 atgataaagt acatgggaga taattcggga attttaggaa tagttcttgc catattatta
     5161 ggagcattag cagcaggacc tgtatatgca gcttttcctg taactgctgt atttattaaa
     5221 aaagggacca aatttagcaa cataatgata tttatgggag cgtggtgtgc tacaaaaata
     5281 ccaactttct tatttgagtt atcagcactt ggatataaat atactttcag tagattatta
     5341 gtgaatttac ctagtattat aattttagca tatttaatag aaggtttatt gagtaagaat
     5401 gatttagaaa aaatatataa taaatttaaa gaatgaagca ttagattttg cttcattctt
     5461 tccggttgta gacaaccgga tagtctacag cttattttca tgctaaaata aatatagtga
     5521 taaagatgat aggaaaaaga aatactgacg aaagacacca aataaagaag aatatataga
     5581 acaagtagaa gatattagac atacaaaagg taataaagaa atttattcta aaagaagtca
     5641 aactatagaa cgggtatttg atgacgcaaa ggaatttcat ggaatgatat atacacatca
     5701 taagcctttt gtcttcaatc taaacaaagg cttttatgcc tttgtttttt ttattataaa
     5761 ataaaatata tgcaagaaaa tttattttaa aatcataata aaagaaaaca tatattatgg
     5821 taagtctata aaattaattt tatagtaagg atatagcatt gaaaagtttg ttaaattttt
     5881 atttataata cttataagta ctataaattt tatttatagt ataataggcg gcttatagaa
     5941 taattttata tatgcagttt ttagtagtaa aactgtcatt ttgtttttat aatgaatatt
     6001 gtaaagaaaa aatacagggg gtagtgacat ggaaaaaatg tacaagtttc ctttaaagat
     6061 gcatgtagga gcaccagatg taccatgtgt taaagaagga caagaagtta aaagaggaga
     6121 atgtatagct gagcctaatg gattgggagc taaaatacat acaagtgtat ctggtatagt
     6181 tgagaaaatt acagatgcag aaataataat aaaagcagat gaaaatggct caaaagattt
     6241 tgttaaaatc aaagaatgtg acaatattct agaaattatt gctgaagcag gtatagttgg
     6301 agctggtgga gctggattcc caacacatat aaaattaaaa gcagatatac cagatggata
     6361 cgttatagca aactgtgtag aatgcgaacc agctttgcat cataatatag catttataga
     6421 aaaagagcct gatacaataa ttaaaggttt aagatatgct atgaaagcaa ctaatgctcc
     6481 aaagggatac atagcaataa aaggcaagca tgaaaaggct ataaaaatat taaaagatca
     6541 tttaaaagga gcttctgata tagaagtaaa agagcttcaa gatatatatc caatgggaga
     6601 agaaagagct ataattcatg ctatattagg aaaatggtta gaaccaactc agcttccatt
     6661 agaagcaaag tgtgttgtaa ttaatggaga gactttagct aatataacaa gagcagtaga
     6721 agatagaaag cctgttatag acaaagatat aacaataata ggaaaattaa aaacaggtaa
     6781 taagcctaat gtattatttg atgtagcagt aggcacaccg atacatgatt taatagaaga
     6841 gtgtggtgga atagatggag aatttggaga agtagtaata gggggaccat atacaggcaa
     6901 agctggagat ataaaagagt ctgtagtgac taaaatgtca ggtggagcaa tagttacaat
     6961 acaactacca gaatacaaag gaccattagg attattagta tgtgcttgtg gagcaaatga
     7021 agaaagattg agagatatag cttctaaaat gaaagcagaa gtagtaggcg ttactaaatg
     7081 taagaatgta gaagaaataa gaggagcaaa taaatgtaaa actccagggg attgtccggg
     7141 acaggttgca ggaataatga aattaaagaa agatggagct aaaagaatac taatatcaaa
     7201 ttgtagtgat tgttcaaata cagttatgtg ttgcgctcca aacttaggaa tcccagtata
     7261 tcatcataca gatcatgtat ttagaacaat agatcataca ttaacaagaa gacttcctat
     7321 agataaaaaa taagtatatc ttattgaata tattgtaagg agatgggtta acatgtcaat
     7381 gtcagcagag catgcagaag agttgaaaaa tgaaccggca gtagtttgtt gtagaacgga
     7441 agaaggcact atattgtctg cagacaactt agaagatcca aatatatttc cagatatggt
     7501 ggattcaggt ttattaaata taccaggaga ctgtttaaag gtaggagaag taataggagc
     7561 taaactatta aaaactatag attcattaac accattaact aaagatatag tagaaggagc
     7621 taaatcttta gatggagatg taagatcaaa atccgaaata caaatagaat caccagagga
     7681 aaaagccatc ttaaaaaata atttaaaagc tggagatgtt ataaaagtag aagatttaga
     7741 aaatccaatg cattttgaaa aacttcagga ttctttatta ataaaatcag atgaaaaggt
     7801 tttaactaga ggggaagtag taggtgcgaa attaactgaa gatgctcctg ctatatcagg
     7861 tgtaacagct tctatgctag agggatttga agaaaaagct ttagaaataa cacaagattc
     7921 taaagaagta gattttaatt cagttattcc tttgaatggc aataggggat tcttaagatt
     7981 aaaaatggaa gaaggtacag gtatttatat agagatacct tttacacaag tataattaat
     8041 taaataaaat tatattaaac agggaatttt aatgatacaa aaatatcatt gaatttccct
     8101 gtttattttt atattagaaa tagatatatt aatgtaaaca atgagatgaa ttactttgat
     8161 ttaaattttt aattaaatag ttaaaataag aaaagatata taaaggataa acatggtaaa
     8221 aatttataaa aagctcatta cattatgtaa aaagtttttt agatttttac tataatatat
     8281 aattttaaag tttaaatatt aaaaaaaata tagaaaaaag ttgctgttaa ttaattgttt
     8341 tataaaataa aacgaataaa tttaaaaaat ttatataaaa aaataaaaat gtcaactttt
     8401 taaacagata tgtcaaaaaa ataacgaaaa tataaaccca atattttctt ttgaaatgaa
     8461 caaagattat ttaaaaattt aaaataaaaa ttaaaagtgt caaaaaaata acattgttaa
     8521 atgtaatata accgttataa gttttattta tacacctaca gcatagctat aacctagttt
     8581 tatagaagtt attaattttt ttaacaaagt tggcatagtt tatgcttaaa atataggtga
     8641 cagtgatttt ggaggtgggt ttatggagaa gttatacaaa ttctccctta agatgcacgt
     8701 aggtgcacca gatgtatctt gtgtaaaaga aggacaaaaa gtgaagagag gtgaatgcat
     8761 agcagagcca aacggacttg gtgctaaaat acatactagt gtatccggtg tagtagaaaa
     8821 gattacagat aaggaaatta taataaaagc ggatgagaat caaacaaaag aattcgttaa
     8881 aataaaaaaa tgcgataatt tagtagatac tgtatttgaa gcagggatag tcggagccgg
     8941 tggagctgga tttccaactc acataaagtt aaaggcagat aataaagatg gttatatcat
     9001 agcaaattgt gtagaatgtg aaccagcact tcatcacaat atgaaagtta tagaagaaac
     9061 accggaatta ataataaatg gtattaagta tgccatgaaa gctactaatt caaaaaaagg
     9121 atacatagca ataaaagcaa aacatgaaaa agcagtaaga gtattagaag aagcattaaa
     9181 aaatataagt aatatagaat taaaattgct taaagattta tacccaatgg gtgaagaaag
     9241 agctataatc aatgcaatat ttgataaatg gttagatgta actgaacttc ctatagcagc
     9301 aaaatgtatt gtaatgaacg ctgaaacttt agcaaatatt acaagagctg ttgaagaagg
     9361 aaaaccagtt atagataagg atataacagt aatagggaaa ctaaaatcag gtaataaacc
     9421 aaatgtattc ctacaagttc cagtgggaac accagttaaa gatttaatag aaaaatctgg
     9481 tggtatagat ggtgaatatg gtgagctagt aataggtgga ccatacactg gaaaagctgg
     9541 agatatagaa aaggatgctg ttactaaaat atctggtgga gcaatagtta caataccatt
     9601 accagaatat aatggaccat taggactact agtatgtgcc tgtggagcca acgaagaaag
     9661 actaagagat gtagcaacta aaatgaatgc agaaattgca ggagtagttg actgcaaaaa
     9721 catagaatat ccaaagggaa aagggaacgg gccaggaaaa tgtaaaacac ctggtgaatg
     9781 accaggccaa gcggctgcag ttatgcagct taaaaaagat ggagcaaaaa gaatattaat
     9841 atcaaattgt aatgattgtt caaatacagt tatgcaaata gctccaaaag ctaaaattcc
     9901 agtatatcat catactgatc atatatttag aacaattgat tatacactaa caagaagact
     9961 taaagaggaa gaaaaataat aaaaaaggag gtaatttgaa atgtcaatga cagctgaaca
    10021 tgcagaagaa ttaaaaaatg aacatgctgt agtttgttgc agaacagaag aaggcacaat
    10081 attatcagca gataacctag aagacccaga aatattccca gatatggtag actcaggact
    10141 attaactatc ccggataatt gcttaaaagt tggagaagta ataggtgcta aattgttaaa
    10201 aactgtagat tcattaactc cgctaacttc agatatagta gagggcgcta aaaaaataga
    10261 tgaagaagac aaagaaggtt ctactactga agaagagtta actgaaggaa atgaaaaagc
    10321 agttttaaaa tataacctaa aaacaggaga tactataaaa gctagtgact tagaaaatcc
    10381 aatgcacttc cctaaacttg tagattctct tttaatttca ttagatgaaa gagtacttac
    10441 aagagaagaa gtagttggag caactttatc agttgataca ccagctttaa ctcctgtaac
    10501 accagatata ttagaaggat ttgaggagga agtaaacatg agtgttgatt caaatgcaac
    10561 agtaagtggt ggaactttaa gaatcaaaat tgctgaaggt agaggaattg atatagaagt
    10621 tcctttaaat ggcaatgtag gtgctggaaa atcagcaaag gttccaacag taaaagctga
    10681 aaaaggtgaa gtagtagcag ctccagctgt agaaggcaac aaagaagtta aattagaaga
    10741 aaaagttata agaagtctta ctagaaaaca ttataaaata gataaagtag aatttggtcc
    10801 tgaaacaaaa atagaaggaa caactcttta tataagagaa ggtgtttctg aagatgctaa
    10861 aaaagttagc ccacttgtaa aaaaagtaga aatagatata ataactccag ataaatacaa
    10921 cacttatagt gaaactataa tggatgtaca accaattgct actaaagaag gggataacaa
    10981 attaggaaca ggtgcaacta gagtattaga cggtgttatt gtaatggtaa caggaacaga
    11041 tgaaaatggc gttcaaatag gtgaatttgg ttcttcagaa ggtatattag aagaaaatat
    11101 tatgtttaat agaccaggat caccagataa aggtgaaata ttcatcaaaa cgcaagtaac
    11161 tataaaagaa aaaactaata tggaaagacc aggtcctatg gctgctcata aagcaactga
    11221 tttcataact caagaaataa gagaagctat gaaagcttta gaggatgaat ctttagtagt
    11281 taatactgaa acttttgaac aaaaaagaag accaggaaag aaaaaagttg tagttgttaa
    11341 agagataatg ggtcaaggtg ctatgcatga caacttaata ttaccagtag aaccagtagg
    11401 ttatttaggt ggtaaaccaa atgttgattt aggaaacgtt ccagtaatgc tttcaccact
    11461 tgaagtatta gatggtggta tacatgcatt aacttgtatt ggacctgctt ctaaagaatg
    11521 ttcaagacat tattggagag aacctcttgt aatggaatgc atgaaggatg aagaattaga
    11581 cctatgcgga gttatatttg taggaagtcc acaaatcaat agtgaaaaat tctacgtatc
    11641 agaaagaatg ggtatgatgg tagaagctct agatgttgat ggtgcttttg ttacaactga
    11701 aggttttgga aacaatcaca ttgattttgc aagccacgta gaacaaatag gtatgagagg
    11761 aataccatgt gtagcattct cattctgtgc agttcaaggc gctctagttg ttggtaataa
    11821 atatatgaaa tatatgatag ataataacaa atcagaaggc ggaatagaaa acgaagtatt
    11881 agaatgcaat acattatgtc cagaagatgc aataagaggt gttgaaatgc ttaaagctgc
    11941 tatggttgga gaagatgtta aaaaaccaga aagagcttgg aatgcaaatg ttaaagaaaa
    12001 taacttagaa ttaatagaaa aagctgaaaa tgtgaaaata gaaagagttt taaatgaaac
    12061 ttcaatacca atgagtgaaa agagaaaaga aaaatacagc acaaagtagg gatataaatg
    12121 aatttaaaat acggtgataa gatcatagaa atggaaggcg ttatcgtaga agtatccgat
    12181 ggtgcagtag ctatagattt taaaggaaga cttggttatt tgaaaatacc aaggagaatg
    12241 ataatatccg attatgaatt aaaagtaggt caagaaattg gacttaatat gagttttgta
    12301 gaagtattat ctgataaaat aaatgaaaaa tacgtaagta atttagaaat acaaaaaaga
    12361 cgaggggtaa aacctgagga tagatggaaa taaacagata atttgaagct agagaaactt
    12421 tcataaataa taatttaaac attcattgaa ggaaggaagg taaggttaaa atgagtttaa
    12481 ctattacaaa aggtttacaa tcagaaatat ttgttcctat aactccagac ccagtatggg
    12541 caccagtaac aaaggaatta aaagatatga cagtagccat agctactgca gcaggagttc
    12601 acttaaaaaa ggataaaaga ttcaacttag caggtgactt cacatataga ttaataccag
    12661 gagatgcaaa gacatcagat atgatggtat ctcacggtgg atatgataac tcagacgtta
    12721 acaaagatat aaatgccatg ttcccaatag atagattaag agaattagta gatgctggct
    12781 ttataaaagc agttgctcca actcatatag gattcatggg tggcggtgga aaccaacaaa
    12841 aattcagaga agaaacaggc ccagaagttg ctaaaatctt aaaagaagaa ggagtagatg
    12901 ctgtattaat gactgctgga tgaggaactt gtcatagatc tgcagtttta gtgcagagag
    12961 cgattgaaaa agaaggaatt cctacaataa taatagctgc tcttccacca gttgttagac
    13021 aaactggtac accaagagcg gttgcaccaa gagttccaat gggagctaat gcaggagaac
    13081 ctaataatgt agaaatgcaa acagcgatag taaaagatac attagaacaa ttaattaaga
    13141 ttccttcagc aggaaaaata gttccattac catacgaata tatagcaaaa gtttagtttt
    13201 gtttccttaa aaataaaaaa tgcaataatg tagtgcagtt ttactgaact cattattgca
    13261 tttgctttaa taaaaaatat aaataaaatg ctctatattt aaaagtttgt tataaactat
    13321 agtgtagtat gagggtttag aaaaagtttt cagaatatat aaaattttcc ttataaatgt
    13381 attgaaaaat cttataggta ttatatatac aatttagaaa attgatgata taatagttac
    13441 ataattatca atatataagt ttttggatat aaatgttaaa cctgtatcaa tctaatgatt
    13501 atgaagttat taaaatggaa aaaggtggtg atgctggtgg aacaagaaat catattgaga
    13561 agattagtta taaaagcttt tcatattact aaagtagagc tttcagatag gacttacata
    13621 gaggataaag ttttatatat aagaaaagat atattagatg gaatattaca acatgaagat
    13681 atggaaggac aagaattaat agaaaaaatt gatttgaata ttataaatcc aaaggaaaga
    13741 cataaatttg tgaattctat aatggatttt tctccagtag ctactaaagt tttgggagct
    13801 ttaggagagg gtataacaca tgtgttaaca ggagtacaag taatgttaac aggagcagaa
    13861 gaatgtggga ttcaggtagc tgaatttggt tcttcagaag gaattttaga tgaacaagtt
    13921 gtttttggaa gaagaggaac tccagccgag gatgatataa ttgttcatat aaatgttaca
    13981 ttgaaaaatg gacaagctac aaataggccg ggaccaatgg cggctcatag agtttgtgat
    14041 ataataatac aagaaattag aaactacctt aaaaaaatta atggtagata ttgtgatgaa
    14101 aagcatgaat attttgataa aataagacca ggcaaaaaga aggttgtaat tgttaaacaa
    14161 gttgcaggtc aaggttgtat gtatgataca ggattatttg ctaaagaacc tggtggacat
    14221 atcggatgca aatctataat agatatgggc aatatgccgg tggttgtaag tccaaatgaa
    14281 tatagagatg gcatattaag ggccatgaat taaggggtga tattttatgg ggataggacc
    14341 atctaccaaa gaaacaacat tacatcattt tagagaccct ttagtagaaa tagtttctaa
    14401 tgatggagat atagatttat taggaattat agttgcaggt acacctcaag caaatgaaga
    14461 aaaggtattc acaggtcaga ggataggagc ttgggcagag gctatgagag ttgatggcgc
    14521 tatagtatcc atagatggat ggggtaacag taatatagat tttgcctcag ctttagaagc
    14581 tataggtaaa agagatatac cagtagttgg tatgagtttt gtaggaactc aagctcaatt
    14641 tgttgttaca aatgaattta tggatacggt ggttgatttt aacaaatcag aagcaggtat
    14701 agaaactgag gttgtaggag aaaacaatgt tatgccaata gatgctaaaa aagctttagc
    14761 atttttaaaa ttaaaaatga aaagaaaaca aaactaagga ggctttaata atgagagcga
    14821 ttaaaacaat tcaaactatt gaatctcaca caatgggaga accaacaaga atagtaatag
    14881 gaggacttcc aaaggttcca ggaaagacaa tggcagaaaa aatggaatac ttagaagaaa
    14941 ataacgatag tttaagaaca atgcttatgt cagaaccaag aggacataat gacatgtttg
    15001 gtgctattta tacagaacca gctgatgaaa cagcagattt aggtattata ttcatggatg
    15061 gtggcggata ccttaatatg tgtggacatg gttcaatagg tgcagctaca tgtgcagttg
    15121 aaatgggaat agtaaaagta gaagagccat atacaaacat aaaattagaa gctccagcag
    15181 gaatgattaa tgctagagta aaagttgaag atggaaaagc taaagaaact tcaattgtga
    15241 atgttccagc tttcttatat aaaaaagatg tagaaattga tgtgcctgat tatggaaaac
    15301 ttacattaga tatatctttt ggcggaagtt tttttgctat ggtagatgct gaaaaagttg
    15361 gaatagatat ttctccagct aattctcaaa aattaaatga tttaggaatg aaaatagttc
    15421 atgcagttaa cgaacaagtt gaaattaaac acccagtatt agaacatata aaaacagttg
    15481 atctttgtga attttacgga cctgcaaaaa gtgaagatgc agatgtacaa aatgtagttg
    15541 tatttggtca aggtcaagta gatagatcac cttgtggaac tggtacaagt gctaaaatgg
    15601 ctttactata tgctcaagga aaaatgaaag taggagaaga aatagtaaac gaaagtatta
    15661 tttgtactaa atttaaagga aaaatattag aagaaactaa agttggagaa tatgatggta
    15721 taataccaga aataactggt agcgcatatg ttactggatt ctctcaattc ttagtagatg
    15781 aagaagatcc agttaaatat ggatttgtat taaaatagta ttaaatattt tatataaata
    15841 aaaaaataaa tgacaattat ttcataatta aaacataaaa taatagtatg aaatatatct
    15901 aagtacaatg cacattgttt atttttctta aataaaaaaa tgttatgcaa tgattactta
    15961 aagatgggct cgatgtttat tgcgtggagt ccatcttttt ttaataaaat cttaatacaa
    16021 aatataggtt cattaaaatc aaataacaaa aaaggagggt ggattataag aaccaagtaa
    16081 agttttataa tgataggata acatttttgg attaggccaa ataaagttct ataataatgg
    16141 ggtaatcatc tttggattag gccaaataat gttccataat aatggggcaa gcatcttaga
    16201 gttatgcaaa ataaagtcct ataataaggg ggtaaatgtc tttaaattgg acaaaaataa
    16261 agtttcataa taatggggga gcatccttgg attagacaaa agaagttcta attttaaata
    16321 acaaggaggg cgtattatga tagtaaaaat tgtttttggg attttgttaa ttttaactct
    16381 ttattttgca ttcatatttt ttaaggattt tgtaaaaaat tcaaaagagg gaaatttaga
    16441 agaaataagc ttttggaaag ctggtgcagt agggtttata gctaattttt ttgatacctt
    16501 aggaataggt agttttgcac cattgaccgc tatgcttaga tttttaaaat taacagagga
    16561 tagagtttta ccaggaacct taaatgtctc ctgtacaatt ccggttgtaa cagaagcact
    16621 tatatttata actgttataa aggtagatcc tgttacttta tttgcaatgt taatatcagc
    16681 tacagttgga gctgtagtag gagctggaat agtttcaaaa tttgatgaaa aaaaggttca
    16741 attaggtatg ggtattgctt taatgatagt tgcatgttta atgcttgcaa gtcaattaaa
    16801 attaatgcca gtaggtggca cagctatagg acttactggg gggaaattag taatagcggt
    16861 aatagctaat ttctttttag gtgcattaat gacattagga ataggattat atgcgccatg
    16921 tatggcttta gtatttgctc ttggaatgag tccgaaggtt gcttttccaa taatgatggg
    16981 gtcctgtgct tatctaatgc cagcagcatc agctaaattt gtaaaagaag gagcatataa
    17041 tagaaaagct tctatggcca taactatatt tggtgttata gctgtattaa tagcagccta
    17101 tatagttaaa gaattaccat taaatatatt aacttggtta gtaatagtag ttattatata
    17161 cacatctact accatgttta aagcctattc aaaaggaaaa atctaaaaac tattcagcat
    17221 aatgtaacaa aatttaagag ttgagtatta ttgcataatc ctttgttcaa aaagtctatg
    17281 ttttgtagaa atttataaat taataaaaaa tctatctgat ttttatttat agtcagatag
    17341 attttttaat tcatttattt tgatgcaaaa ttatttttag actgaatttc gcctttatct
    17401 cttctttgtt catatttact aaacattctc caaccaatcc agcttagaag tattggtcca
    17461 cctatactta ataattcaaa gaatgcaatt tgtcctgtgg ttgtataatc tgacggtggg
    17521 aagaatgaag ttacaattcc aaatattaca cttattaatc ctacaatgga tacaaaggtt
    17581 gaaaattgct ttgattttga tatttcgtaa aattcctctg tggattctcc cttagcttgt
    17641 aatttctcca ttttctttaa tctaatgtaa gatgcaaaca ttaataaata agggattaag
    17701 cctgttatag ctgtcattat tataagtatt gaatatatag cattaactgt tggtaaaaga
    17761 gttgtaacta ttattactat tgaaatacct ataccttgta ccaataatgc attaattggt
    17821 acgccatttt tatttgtttt tgttaaaaat ggaggtaaaa caccattttt gctagtttca
    17881 aataacatag ttataggaga cattatatat aaactaacgc cacctaaagc ttctatagtc
    17941 ataagtattg ccattaaagt taggaaccat tgtcctatac caaactgctc tgttattaat
    18001 ctaaatgctt ctataagtcc atttgcagca cctatttttt ctggtgatac tacaaaagta
    18061 atggcagatg aacatagtat atataaaata gttataaaga tagcacagaa tataattgct
    18121 ttagggattg ttttttttgc gtcttcaact tcgccagcaa aggctgctgt tacttcagca
    18181 cctgttaagc caaacattac agaagatagt aatgctaaat tagctatatt actgaaatcg
    18241 ggtatcatgc cttgaagagt gtagggtgtc gcaagaggtc ttttaagaac gaaagcagat
    18301 gcgtaaccta atattataat taataaagca ggaagtacac tgccgacaag tccacctata
    18361 actgcaaata ttttactatt tccagtgcct ctaaaactcc atatagttat aaaccagaag
    18421 attcctaaaa ccatgaataa attataaagt ttattatttg caagacttgg atctataacg
    18481 tatgcaaatg taactgctgc atatgttaca aatccgggat aaaagaatag tttactaacc
    18541 cagttaagcc aagatactaa aaaacccatt ttttcaccat aggcttttgt aacccatacg
    18601 cttaagccac cctgttctgg gtatttacct cctaattctg cagcgaccaa tgcgctagga
    18661 ataaagaata gtaatgctgc tattccccat aatactgcac aggaggcgcc atatttagct
    18721 gaaacagcta cccatcttaa tcctaaaata gctgtcatgg tcattaaaac catgtctttg
    18781 aatgtcaagg actttttcat ttaataatca cccctattgt aaaatttttg ataatattgt
    18841 tgaattgtta aatactcttt aatattatgt tatttttatc acaaaatcaa gacatttttt
    18901 taacaaaatc tacaaagtta aacaaagtta agtaaaacta tgaaaaagta ttttatttca
    18961 tagaaaagga ttacacaaac aagctattat aataaattag ttattataag gcttgaattc
    19021 tataatttta tttattatac taataaatat gctaggaaat atggtatctt taataaagaa
    19081 aatgctataa cattgttaaa aaaacaaaaa aatacaggtt tatttgaaaa aaatatcaaa
    19141 aaaacaagtg aaaataaaaa caaatttatt gaagttaaaa attaaatttt tgatataagt
    19201 tgacatctta ttgcaattgt tttgatattt agtaaaaaaa tacaaattta aaaaatattt
    19261 agttataacc tagttaataa tgttgataat attatattta tataatatat atataacccc
    19321 aatacaattt aaaatatatt acgttaagga ggaaatttaa aatgagtttt caattaccaa
    19381 aatttacacc accagatttt acacaagatg ttcttgttaa ggcaccagat gttaaaatag
    19441 gtgaagttga aaaagatgga gtagctcctc aaggatttca tataacttct gtattaccag
    19501 aatattttaa ggttaaaggt gaatgggttt taccaactca aacatctcta gattgtgctg
    19561 caatagttaa agatgacaac actgtagaag ttgtagaatt cagaagcctt aaagttggag
    19621 ataaagttat attaggaaaa tctgtagatg gaagcgaagg tatctacaaa tatgctgaag
    19681 gttttgataa tataccaaag gttggattcg gaagaactgt tgaatcatct ttctcaaaag
    19741 actacaaaga attatatgaa atattaaaac atgaaaaaga aaacaatgga catatagttt
    19801 gggttttagg acctgctgtt gtatttgact atgatactag agtagcttta tcagaacttg
    19861 ctgaaaaagg atttgtaaac gctcttatgg ctggtaacgc tatggccact catgatttag
    19921 aaggaggact tttaggtact gctttaggac aaaacatata cactcaagaa tcagttccaa
    19981 tgggtcacta taatcactta gaccttataa acgaagctag aagagctgga tctatagaag
    20041 ctctactttc tgaaggaaac gttaaagatg gatttataaa agcttgcata gaacataata
    20101 ttccaatagt tcttgcagga tcaataagag atgatggtcc acttcctcca gtttatcaca
    20161 atgtaacctc tggacttgat gctatgaaag aacaagctca aaaagcaact gttataattt
    20221 gtcttgctac agttcttcac tcagtagcaa ctgcaaactt agcttcatct tataaagttg
    20281 tagatggtaa ggtaagacca gtatatgttt actctataga tattgctgaa tatgcagtta
    20341 accaagtagc aacagctaga gaacatgtag gtgttaaaac aatagttact aacgttcagg
    20401 actttgttgt taatgttcaa aagaacgttc ttaaataaga gattataaac acttaatttt
    20461 gaaaattact aagatacatt aatatattat taggaggaga ttttaaatga gtttcgaatt
    20521 accaaaattt acgccaccag attttacaca agattttctt gttaaagcac cggattgtaa
    20581 aactgaagaa gtagttatag aaggagttgc tcctagacac taccacgctt tatcaatata
    20641 tcctgaatac tttaaaatta aagggaaatg ggtaatagct aacgaaagcc gtatggatac
    20701 tgttgcaatt gttactccag aggatgatat agaagttgta gaatttagaa atcttaaact
    20761 tggagataaa gttgtagtag gaagaactga agatgctagc gaaggtatat acatgtatgc
    20821 tggtggattc gtagctaaag acggaaattc agatactttt gcatttagaa gtggtagatc
    20881 aagagaaaca gctttctcta aagactatga tgatttatat gaaataatga aatatgaaaa
    20941 agaacataac ggaaaaatca cttgggttct aggaccatca attgcattag atgatgaatc
    21001 aagagcagct tttgcttccc ttgtagaaaa cggatatgtt aatgccattt tatcaggaaa
    21061 cactcttgca acctatgact tagaaaaagg aatgttcgga acagttttag gtcaagaaac
    21121 ttttgaagct gaaaaaaatg ctcattacaa ctatatggaa gctataaacg aagctagaag
    21181 agctggttct ttagaagaac ttatggcttc tggaaaagtt aaagatggta tattaaaagc
    21241 ttgtgtagaa aaagatgttc ctgtagtact tgcgggcact ataagagata gattcactct
    21301 acctaacgtt tacgataatg catatgaagc tcaagatgct atgagaaaac atacaagaaa
    21361 atctacaatg cttatatgtt tatctacagt actacataca atagcttcag gaaatatgac
    21421 tccatcttac acagtaagag atggtgttgt tagacctgta tatatctatt ctatagatat
    21481 acaagaattc tctgttaata aactatcaga tagaggtact ctagaagtta aaactctagt
    21541 tacaaatgct caagacttta ttacaaatat agctaaagca ttagttaaat aacttaaaaa
    21601 aatttttctg tatactaaat tttagtaaaa aagagagtct ttttaaagat tctctttttt
    21661 attgtacaga tattgattta aaatataata attatttatt tttaatttta aatttaatat
    21721 atttaatttt actagtttac ttaaaaaaaa tttataagaa ctattgactt taatgcttga
    21781 tgaaactata atagttacaa cgaaagcgat aaaaatgaga agtaaatcaa ttttttttat
    21841 aatagatgta acttcataag ttacatctgc taaataattt tataatttgt tgcaaattaa
    21901 ttaattacca taatgaatgc attgaaagag ttttttaagg tttctttgaa gaggaattag
    21961 atattggaag agttaagata ttatctgaat taactgaaga aataacaaag agataactgt
    22021 ttgtgcagtt ggagatgaaa ttacaaatag aattatggga gtgataaaaa tattgaaaaa
    22081 attgtccttt aaaatgaaat tattaattac tattttacca gttgtaataa ttggaatgtc
    22141 aattttgagt tttataacat tttatgaatt tagaaaaaat attgaaaatg aacttgtcaa
    22201 caataaattg gaggaaggga aaaaactaac tgagagtata aacaattggt tggaaggaaa
    22261 acttttagaa gtaagaagtg ctgctaatac acctacggca aaactaatag aaacagatgt
    22321 tgctgctgta gataacttta atgcagaaag aattaaattt ttagaaaaaa attatccagg
    22381 agaatatgac aatgcagcag caactttatt taataatgat ggtaaatcta gagctcaata
    22441 ttcaaatgga aagtttgtaa atggtgatgt atcagaaaaa acatggtaca aggatttaat
    22501 gagtggggta ccatataata tatctaatcc tgtagtatca aaggggactg gtaaaacttt
    22561 ggttgtaata ggagttccaa ttaaaaataa atcagaaaaa acaataggaa caatgatatc
    22621 tgctgtgaat cttttacata ttaaagaaaa agttaaggaa tttaaatttg gtgaaaaagg
    22681 atatagttta ttaattggaa aggatggaac tattcttgaa catccagata agtcattagt
    22741 aatgcagaaa aagatatcag aaataaaaga tgaaaatata caatcattag gaaaagaaat
    22801 gatgaaaaat gaatcaggtg tatttagatt tggaagtgga gataataaat cgattgtatt
    22861 ttataataaa gttcctctat cagggtggaa tgtagcaagc gttgtgtctg aaaaggaatt
    22921 gtttgctcct ttaaataaat taatgttaac attaatttta ataacaatag taattgtatt
    22981 tattgttgca acagtaattg tatttgtagc aaaacaaatc acattaccat taactaagtt
    23041 atctgatttt gcagaagaaa tagcagaagg aaatcttaca aataaattag aagttcatgg
    23101 gcaagacgaa atttctaagg tgacaaaagc actaaataat acagtttcaa agcttaagaa
    23161 aatgataggt gatataagta gttcggctaa tgatgttatg gtaatatcta atggtttagc
    23221 attatcaaca agtgaatcat taaagggaaa tgaagaagtt tcacgaagta tgcaagaaat
    23281 agccacaggg gctgtatctc aggcagaagg ggcaagcaaa gcatctattg taacaagaga
    23341 attagttgaa gatataaatg aaatatctaa aaaatgtaac tatatgattg acatagtaga
    23401 aaaatcaact aatagaagca caaaagtttc acagggagtc caacacactg tagatagtat
    23461 aaagaacata gctacaacaa ataaacataa tgttgaagaa attcaaaatt tattaaatca
    23521 atctaaagaa ataggacaaa ttgttgatgt aataagtgat atatctgaac aaactaatct
    23581 tttatcactt aatgcagcca ttgaagctgc tagggctggt gcacaaggta gaggatttgc
    23641 tgtagttgca gatgaggtga gaaaattagc agaacaatca agtaattctt caaaaaggat
    23701 agtagagctt attaatggaa ttcaaaagca aattgaaatc atatcaaata aaatgaattc
    23761 tggaacaagt gaagttatgc atggagttaa aatggcaaca ttaattggta atgattttga
    23821 agaaatagag aaagtattta atgaagttaa taatattgta ttagaggtat cagagtctac
    23881 taatacaatg gaaaagaaag taaatgttac agctgatatt ataaataatg ttgcatctgt
    23941 aacagaagaa aattcatcag ctacagaaga agtcactgca tcaaatgaag agcaaattgc
    24001 ttttatgcat caaattgtag actcaactta tacattagaa gaattagtta aaaaacttaa
    24061 ggatacagta tataaattta aattatccta gatagaatta aaagtaattt atataggaag
    24121 cttataatct tacaaaataa agattataag ctttttttat taaatctgtt agaaatatct
    24181 acaaaaatag ataaaaacta tagtaatttt gcaataaatg tcttataata taagaggtac
    24241 gagatatcat ttaaaagggt agtgcaaaca tcattgaaaa agaagttgtt actattcttt
    24301 gggggaatat tcatttatct attttataaa aaaaattaca cttaatgaaa aggtttactg
    24361 gtaaattaaa aaaatactat ggagaaggta gggggaataa caatgataac aaaattatta
    24421 ttatcagtat tactagtttt gacaagctat tttttatttt tctttttaaa ggattacttt
    24481 aaatcattaa aaaaaggtaa tctagaagac aataattttt ttattgtagg aattataggt
    24541 ttagtagtaa atttttttga tacattaggt atagggagct ttgcgccgct aacatctatg
    24601 cttaaatttt ttaaacaaac agaggataaa gtaataccag gaactttaaa tgtaggatgc
    24661 actgtgccta tgattttaca agcttttata tttatgacag gcataaaggt ggaacctgta
    24721 acattagttt ctatgataat agctgctatg ataggctctt tatttggtgc ggaaatagta
    24781 tcaaaattag atgaaaaaaa agtgcaattt tgcatggggg tatctcttct aattgtagct
    24841 ttaataattt tagcaggaca attaaattta atgccagcag gtggtaatga tataggtctt
    24901 catggtacta aattgataat agctatagta ggtaatttta ttttaggtat acttatgaca
    24961 gtgggtatag gattgtatgc tccgtgcatg gctttagtgt gtgtgttagg tatgaatccg
    25021 aaggtagctt ttccaataat gatgggatcc tgtgcatttt tattacctat gtcttcaaca
    25081 aagtttgtaa aaaataatgc ttatgataaa aaggcatcta tatccataag tatatttgga
    25141 gtagtaggag ttttaatagc agcatttata gtgaaagaac ttcctgttag agctttaact
    25201 tggatggttg tttgtgtaat aatgtatact tctattacta tgtttaaagc ttattactct
    25261 aaaaaagaaa gttatgaaac tagagaagaa ttagcttaat agtatatata aataaaattt
    25321 ttaaaagaaa aataaaaaaa agtatagtga ttaaattata tatataataa tgtaggtttt
    25381 tattttttat ccgatgacta tccgctctaa tactcccatc ttcttcaaag tgggagtaaa
    25441 gagcggatac gtccctggat aacgatttct aagcttcaga atgagtaaaa actcactccg
    25501 aagccaagaa ctctgtttat aaaaagatat ataaaattgg gttttataat tggaacttag
    25561 agtttgtact aaaattttag tataaactct tatttttttt atttaaagta tttaatagtt
    25621 ctatgttata aatatagagc tacaaatagg aggactcaat atagatttga attttaggta
    25681 ttctcctttt tatatataac atatagattt tacctaatta tcattttata taaaaattag
    25741 tagccttatt tattgaaaat gaattaaaaa gaataaaata aaaaaaatag tttaaaataa
    25801 aatatgaatt taaaaattac ttataattaa ataaaaatct ttgtagaaac attagtaatg
    25861 agaatgttta caacgtggtg tcagaaaata ctacactata attcaaacaa tgttattaaa
    25921 aatacaaata gataaggctt taattgataa aaaaaaataa taatgtctaa aagctgacac
    25981 attatccgta aaagtgtcaa aaaaaagaca aaaatatatt gaaatttata agaagtttat
    26041 gcgaaaaaag ggctttttat aaaaaataac atgtaaaaag gtataaaaaa ctaattattt
    26101 tgtgtttttt ttaacttttt ttatttaaat tatagatttg gcataaacat tgctatataa
    26161 tataagtgtg tgtagataga tcaaggaggg ataccatgga aaaattgttt agttttcctc
    26221 taaggatgca cgtaggtgca ccagatgctc cctgtgtaaa agagggacaa aaggttaaaa
    26281 gaggagaatg tatagcagaa ccaaacggac ttggtgctaa aattcatact agtgtgtccg
    26341 gtatagtaga aaaagttaca gataaagaaa tcataataaa agcagatgaa gctcaaacaa
    26401 cagaattcgt taagataaag aaatgcgata atttagtaga tactgtattt gaagcaggaa
    26461 tagttggagc cggcggagca ggtttcccaa ctcacataaa gctaaagtca gataacaaag
    26521 atggctacat tatagcaaac tgtgtagaat gtgaaccagc acttcatcat aacataaaag
    26581 ttatagaaga aacgcctgaa ctaataataa atggtgttag atatgcaatg aaagccacta
    26641 attctgcaaa aggatacata gctataaaag ctaaacatcc tgaagctata gcttcattag
    26701 aaaaagcttt aaagggagct actgatgtag aagttaaacc tcttgctgac ttatatccaa
    26761 tgggtgaaga aagagctata atcaatgcaa tatttgataa gtggttagat gtaactcagc
    26821 ttcctataga agcaaaatgt attgtaatga atgctgaaac tttagcaaat attacaagag
    26881 ctgttgaaga aggaaagcca gttatagata aggatataac tgtaatagga aaactaaaat
    26941 caggtaataa gccaaatata ttcttacaag taccagtggg aacaccagtt aaagatttaa
    27001 tagaaaaatc tggtggaata gatggtgaat atggtgaact agtaataggt ggaccataca
    27061 ctggaaaagc tggagatata gaaaaggatg ctgttactaa aatatccggt ggagcaatag
    27121 ttacaatacc attaccagaa tataatggac cattaggact actagtatgt gcctgtggag
    27181 ctaacgaaga aagattaaaa gatgtagcaa ctaaaatgaa tgcaaaaatt gcaggagtag
    27241 ttgactgcaa aaacatagaa tacccaaagg gtaaaggaaa tggaccagga aaatgtaaaa
    27301 cacctggtga atgaccaggc caagcggctg cagttatgca gcttaaaaaa gatggagcag
    27361 aaagaatatt aatatcaaac tgtagtgatt gttcgaatac agttatgcaa atagctccaa
    27421 aagctaaggt tccagtatat catcatactg atcatatatt tagaactatt gattacacat
    27481 taacaagaag acttccacag gaataacaaa aaaataaaaa aaattaggag gttatgtctt
    27541 atgtcaatga caccagagca tgcagaggcg ttaaagaatg aatctgcagt agtatgttgt
    27601 agagcagaag agggaacagt attaactgct gacaacttag aagatccaga aatattccca
    27661 gatatggtag actcaggtct attaactata ccagctgatt gtttaaaagt tggagaagta
    27721 ataggagcta aattgttaaa aactgtagat tcattaacac cattaactcc agatataatt
    27781 gaaggagcaa aaacaatagg tgattcagaa gataaggctg aagaaatttc agaagaatta
    27841 actgaagaag atgaaaaggc agttctaaaa tataatttaa aagcaggaga tactataaaa
    27901 gctagtgatt tagaaaatcc aatgcacttc cctaaacttg tagattctct tttactaaca
    27961 ttagatgaaa gagttcttac aagaaaagaa gtagttggag caactttatc agttgatatg
    28021 ccagctttaa ctcctgtaac acctgatata ttagaaggat ttgaggagga agtaaacatg
    28081 agtgctgata cacaagcaac aataagtggt ggaactttaa gaatcagaat agctgaagga
    28141 aaagggattg acatcgaagt tcctttaaat ggaaatgtag gtgcaggaaa atcagtagct
    28201 gttccagcag taaaagctga aaaaggcaca gtaactgcag ctccagtagc agtagaagct
    28261 aaaaaagaag ttaaattaga agaaaaagta gtaagatcag ttacaagaaa atactacaaa
    28321 atagacaaag tagaattagc taaagaaact aaaattgaag gaacaactct ttatataaga
    28381 gaaaacatct gtgaagatgc attcaatgta gatcaattag ttaaagatat aaaattagaa
    28441 ataataactc cagataaata caacacttat agtgaaacta taatggacgt acaaccaata
    28501 gctactaaag aaggttcaga tgctaagtta ggtgaaggcg ttacaagagt tatagatgga
    28561 gctattataa tggtaacagg tatcgatgaa gatggagttc aagttggtga atttggttct
    28621 tcagaaggta tattagaaga aaatattatg tggggaagac caggtgctcc taataaaggt
    28681 gaaatattca tcaaaactca agtaactata aaaagaggaa caggaatgga aagaccaggt
    28741 ccattggctg ctcacaaagc aacagatttc ataactcaag aaatcagaga agctttaaaa
    28801 gctgttgaag atgattcatt agtagttaac actgaaactt ttgaacaagt aagaagacca
    28861 ggaaagaaaa aagttgtagt tgttaaagaa ataatgggtc aaggtgctat gcatgataac
    28921 ttaatattac cattagaacc agttggagta ataggagcta aaccaaacgt tgatttagga
    28981 aacgttccag taatgcttgc gccgacagaa gtattagatg gtggtatcca cgcattaact
    29041 tgtattggac ctgcttctaa agaatgttca agacactact ggagagaacc tcttgtaatg
    29101 gaatgcatga gagatgaaga agttgattta gcaggagtta tatttgtagg aagtccacaa
    29161 atcaacagtg aaaaattcta tgtatctgaa agattaggta tgatggtaga agctatggat
    29221 gttgatggcg cttttgttac aactgaaggt tttggaaata accacattga ctttgcaagc
    29281 cacgtagaac aaataggtat gagaggtgtt ccttgtgtag cattctcatt ctgtgcagtt
    29341 caaggtgctc tagttgttgg taacaaacac atgaaataca tggtagataa caacaaatca
    29401 gaaggcggaa tagaaaacga agtattatct tgtaatacat tatgtccaga agatgctata
    29461 agaggtcttg caatgattaa agcagctatg tctggagaag aagttaaaaa accagaaaga
    29521 gcttggaatg caaatgttaa agaaaacaac attgaaatga tagaaaaaac aactggaaat
    29581 aaaattgata gagttttaaa tgaaacttca ataccaatga gcgaaaagag aaaagaaaaa
    29641 tacgctacaa agtagggata taaatggatt taaaatatgg tgataaaatc ctagaaatgc
    29701 aaggtgttat tgtagacgta tctgatggag cagtagccat agatttcaaa ggaagacttg
    29761 gatacttaaa ggtaccaaga agaatgataa tatctgatta tgaacttaaa gtaggtcaag
    29821 aaataggctt aaatatgagt tttgtagaag tattatctga tgaaataaat gaaaaatatg
    29881 taagtaattt agaaatccaa aagagacgtg gtctaaatcc tgatgaaaga cataaataaa
    29941 tttataaatt gaagggaagg ttactagaat gaatattgta aagggattac aatcagaaat
    30001 atttgttcct ataactccta acccagtatg ggcgccagtt acaatggaac taaaagatat
    30061 gacagtagca ttagctacag cagcaggagt tcacttaaaa tcagacaaaa gatttaattt
    30121 agcaggtgac ttcacataca gattagtacc aggagatgca aaaacatcag atatgatggt
    30181 atctcacggt ggatatgata acggagacgt taacaaagat ataaatgcca tgttcccaat
    30241 agatagatta agagaattag tagatgcagg ttttataaaa gctgttgcta aaactcatat
    30301 aggattcatg ggcggtggcg gaaaccaaca aaaattcaga gaagaaacag gcccagaagt
    30361 tgctaaaatc ttaaaagaag aaggcgtaga cgctgtattg atgactgctg gatgaggaac
    30421 ttgtcataga tctgcagtta tagtgcagag agcgattgaa gaaataggaa ttcctacaat
    30481 aataatagct gctcttccac cagttgttaa acaatctggt acaccaagag cggttgcacc
    30541 aagagttcca atgggtgcta atgcgggaga acctaataat gtagaaatgc aaacagcaat
    30601 agtaaaagaa acattagaac aattaattaa gattccttca gcaggaaaag ttgttccatt
    30661 accatacgaa tatatagcaa aagtttaata attaaaaaag agctctactt ggtaaagtag
    30721 agctctttaa aaaaatgcct aattatacaa attgtatttg aaatatttaa atggaaataa
    30781 attaaagaaa ttcctgcata aaatcaatat tgttttaaat ttatcaaaat gaaaaggatt
    30841 tcacaaaata acaataatag ttttaatttt gtgaaaattt aaagcaatat aaatatagag
    30901 tgttatttca aatttttcta aaatttagtc agttatataa tactatttaa gtaatgttaa
    30961 aaaaatatca aaaaacatga aaaaatctat agaaaaaaat ataaatttgt attaaaatta
    31021 tagtataaaa aataaataaa aagaggtgta gaaaatggta aaaatagttt taggtctttt
    31081 aattatttta acagtctttt ttgcagttgc atttttcaaa gattatatta aagcaactaa
    31141 agaaggaaat attgaaaaaa ccaatttttt tgcattagga acagtaggat ttataactaa
    31201 tttttttgat actttgggaa taggaagctt tgctcctact acagcattac ttaaaaattt
    31261 taaacttaca caggacagaa ctttaccagg tacattaaat gttgcatgta ctgtaccagt
    31321 tgctgtagag gctattttat ttataaatgg tatagaagta gagcctgtaa cattattttc
    31381 tttattaata gcagctacag caggtgcggt agtaggtgca ggagttgtat ccaaactaga
    31441 tgagaaaaaa gttcaatttg gtatgggagt ggctcttgta atagtggctt tagtaatgct
    31501 tgcaggacaa ttaaacttaa tgccagcagg tggagatgct actggacttc atggtgtaaa
    31561 gcttatagta gcaattatag gtaattttat attaggcgct ttaatgactt taggaatagg
    31621 tttatacgct ccatgtatgg ctttagtata tgctttagga atgagtccaa aggttgcttt
    31681 cccaataatg atgggatctt gtgcattctt aatgccggca gcatcactta agtttgtaaa
    31741 agaaggagct tatgatagaa aagcatctat ggctataact atatttggtt tagtaggtgt
    31801 atttatagca tattatttag taaaatcatt accattggat atattaaaat ggttaataat
    31861 tgttgttata ttatatactg cagttatgat gtttaactca tcttctaaag ctaaaaaagc
    31921 ggtaaaggct taaaaataat gttttagatt taaattatat ttgtaaagct ttaaaataat
    31981 taagtgttaa aaaccaggtg aaatttaaat ttcacctggt tttttttcaa gtttataatt
    32041 ttattgttga aaattttaat aaaaagtgtt tatactatat atatgtgtat tcatatttat
    32101 ccataattag cagatagaaa tactttattt gtataattat aaataaatta atagataaag
    32161 tgaaaaaata ttacaataat ttgcataaaa cttgtgaaat aatatattta tttcatagtt
    32221 aactgtaaat tttatttaat ttttatattt gaagggagta gttttaatgg acttaatgaa
    32281 aagcttatgg gaaaaagcta aaagtgacaa aaagaaaatt gtacttgcag agggagaaga
    32341 agaaagaaat attgaaggtt gttcaaaaat attaaaaaat gaattagctc acatgatttt
    32401 aataggaaat gaagaaaaaa taaacgaaac agcaaaaaaa ttaaatgttt ctatagatgg
    32461 tgcagaaata atagatccac agacttcaga aaaagtttct acatatacaa aagaatttta
    32521 tgaattaaga aaacataagg gcgttactat ggaaaaagca gaacaaatag ttaaagatcc
    32581 tatatatttt gctacaatga tggttaaaat gaaggatgca gatggattag tatctggtgc
    32641 tatacacact acaggagatt tattaagacc aggactacaa atagttaaaa cggctaaagg
    32701 agcctctgtt gtttcaagta cattcataat ggaagtacca aattgtgaat atggtaaaaa
    32761 tggtatgctt ttatttgcag attgtgctgt aaatcctaat ccaacagcag atgagttagc
    32821 ttcaattgct atatccacag cagaaactgc taaagcttta tgtgatatgg aacctaaagt
    32881 agctatgtta tctttctcat caaagggaag tgcaaagcac gacttagtag ataaagtagc
    32941 agaagctaca aaaatagcaa aagaaaaaag accagatctt gatatagatg gggaattaca
    33001 attagatgcg gctatagtac aaaaagttgc agatttaaaa gctccaaata gcaccgttgc
    33061 aggaaaagct aatgttttag tattcccaga cctacaagca ggaaatatag gatataaatt
    33121 ggttcaaaga ttcgcaaacg caagtgctat aggaccaata tgtcaaggtt ttgcaaaacc
    33181 aattaatgac ctatcaagag gttgtagcag tgatgatata gttaatgtag ttgctgtaac
    33241 agcagttcaa gcacaaaata tgtaattaaa tattttaatt tttatatgat caatttattt
    33301 attattttag atgataaatt aattgattaa tatcacaaat aaaaaataga tttgtttata
    33361 ataaaatttt atataaaaca tatagatgaa gggtggaaaa ttaatgaaaa tattagtagt
    33421 taactgcgga agttcatcat taaaatatca attaatagat atgacttctg aagaagcttt
    33481 agcaaaagga ttagtagaaa gaataggaat agaaggatct atattaactc aaaaggttaa
    33541 tggagaaaaa tatataatag aagaacctat gaaagatcat aaaaaagcta tagagttagt
    33601 tttaaaagca ttagtagaca aagagcatgg tgtaatatct gatatgtcag aaatagcagc
    33661 agtaggacat agagtagttc atggtggaga aaaatatgct agctcagtac ttatagatga
    33721 tgaggttatg aaggctttag aagattgtgt taaattagca ccacttcata atccaccaaa
    33781 cataatagga ataaatgctt gtagagaact tatgcctaag actccaatgg tagcggtatt
    33841 tgatacagca ttccatcaaa cattaccaga ttatgcatat atgtatccat taccatatga
    33901 attatatgaa caaaatggta taagaaaata tggcttccat ggaacatcac atagatatgt
    33961 atctagtgtg gcatcagaaa tgatgggaaa agatctaaaa gatattaaag taataacttg
    34021 tcacttagga aatggagcaa gtttatgtgc tgtaaaagaa ggaaaatcag tagaaacttc
    34081 tatgggattc actccacttg caggattagc tatgggaact agatgcggag atatagaccc
    34141 agcaatactt cttttcatgg aaagagaatt aaaaatgtca ccagatgaag tagataatgt
    34201 tataaataaa aaatcaggtg tattaggaat atcaggagta agtagtgact ttagagacat
    34261 agaaggtgct gcagaagaag gaaataaaag agctaaacta gctttagatg tatatcatta
    34321 tacagtaaga caaacaattg gtgcttatac agcagtatta aatggtgtag atgctatagt
    34381 atttacagca ggactaggag aaaattcagc agcaagcaga gaagaaattt taaatggatt
    34441 agaatactta ggtattaaga tagatgccga aaagaataaa caaagaggaa aacaaataga
    34501 aataagcact gaagattcaa aggtaaaggt attcgttata ccaactgatg aagaattaat
    34561 gatagcaaga gatactaaag aaataacagc taaatagtat ataatataag ttataaatat
    34621 aggtgtaata actttgattt acttataaaa tacttgactt tttaatatgc cctttatata
    34681 ataaattgtg gttgctataa ttgaggtgaa ttttatgaat ttagatgtat cggatttaat
    34741 aaaaaaaata aaactaagta aagatgttca tctgaagtta gaagatcaaa gaaaattttt
    34801 tgatggagat gaagaaattc tttatttaga agcaccaaca ttagacgggg tagttagtat
    34861 atctaaagat atattaacct tagatggaaa gttaagtgca gaaattgagc tttcttgttc
    34921 aagatgtctt caaaagttta aacaccatgt tgacacagag gtacatgaga gttttacaaa
    34981 taatccccaa tgcgaagatg atgagattat gttactaaaa aatgaagcta ttgatgttac
    35041 agaggttata gaaaataaca taattataga attaccaata aaaagactct gtaaggaaaa
    35101 ttgtaaaggc ttatgccaac aatgcggtgc taatttaaat ttttcaaagt gtaaatgcga
    35161 aaaagatata gatccaaggt tggcaaaact aaaagacttt ttttctgctc agtaaggagg
    35221 tgtttacagt gggaaatcca gcgagaaaaa cttcaaaggc aaaaagagat tctagaaaag
    35281 ctcaaacttt caaattaagc ttaccaggaa tcgttgaatg ccctcaatgt cacgaaatga
    35341 aacttgctca tagagtatgt aaaagttgtg gatattacaa tggcaaagaa gttgtatcaa
    35401 acgataaata attataaaaa agaaagtcgt aaggctttct tttttttctt gtgaaagaaa
    35461 aaaaattagc ttatacttta tagtaggaag gaagtgatac tatgataata gctgtagatg
    35521 gtatgggagg agattttgct ccagaattag tagtagaagg atgtatacaa gctgtcaagg
    35581 aatatgaagg catacatata ataataacag gtaaagaaga attaataaaa aatgaattag
    35641 ataaaagaga atataaagga aacaaaatag agatactaaa tacaaaggaa gttataggta
    35701 ctgatgaagc accagtaaag gctataagaa ggaaaaaaga ttcaagtatg gtgaaagctt
    35761 tagaattagt aaaagaaggt aaagctcaag ccgttatatc cgcaggaagt acaggagcat
    35821 taatggcagg agctactttt gttttaggaa gaataaaggg tataaataga gtttgtttag
    35881 caccattact tccaggagct aaagctcctt ttatgatagc agatgcaggt gctaatgtag
    35941 attgcaggcc agaatattta gttcaatttg ctatgatggg gaaagtatat tttgaaagtg
    36001 tattaggtgt taaaaatcca acggtagggt tggtaaatat aggtgctgaa gaagaaaaag
    36061 gtaatgaact tacaaaagcc gcatataaat tattaaagga tacagatttt aattttatag
    36121 gaaatataga accaagagat ataccaagag gagaaactaa tattgcagta tgtgatggat
    36181 ttataggaaa tactgtgtta aaaacttatg agggagtagc ctcaaattta ttttctatgt
    36241 taaaagatga aataatgtca tccaccagag gaaaaatagg aggagcactt ttaaaacctg
    36301 tatttaaaga ttttaaaaag aaatttgatt atacggaata tggtggatca ccttttctag
    36361 gggctaaggg tatatgtata aaagctcatg gaagttctga tgctaaagca tttaaaaatg
    36421 ctataagaca ggcaaaaatt tgttatgata aaaagataat tgaagaaata gagaataatt
    36481 tagaaaattt aatagaaaat aatatataat ggaacttaat gaatatattg acgtagaaat
    36541 agttatgtaa tattatttat gtataaagca ttaggaggtg acacaaatga tttttgaaaa
    36601 aataaaagct acaatagcag aacaattaag tatagatgaa gaggaaataa ctatggaatc
    36661 atcttttatt gatgatttag gtgcggattc acttgatata gttgaattaa taatggcatt
    36721 agaaactgaa ttcgatttag aaataccaga tgaagacgca gaaaaaattt ctacagtggg
    36781 agatgtagtt gactacataa aatcacatac tgaggaataa ttgattttta tccccgcctt
    36841 tactagcggg gattttatat taaaaaatat aattaaaaga taagtttatt cttgagttta
    36901 tttaataaat atactgaaga atgaacttct agggagtgaa aattttgaaa aatagacagg
    36961 atattttgaa agaacttcag tacaaactta aagtatgttt taaagatgaa aaattattag
    37021 atgtggcatt aacccatagt tcctatgcta atggtaaaaa aaatataaaa tattatgaaa
    37081 gattggagtt cttgggagat tccgtattac aacttataat atcagagcat ttatatcaaa
    37141 aatatgaaga taaaaaagaa ggagaactca ctagaaagag ggctataata gtctgtgaaa
    37201 attcccttta cgaaatggct aaaagatggg atttaggttt ttatttgcaa atgagtaaag
    37261 gggaagaatt gacaggaggc agagagagag tatctatatt agcagattgt gtggaatcta
    37321 taatagctgc tatatattta gataaaggat tagatgaagc aagagaattt gttatgaaaa
    37381 atttcaagga aataatagaa aaagccatga gagatgaaat aatactagat tataaaacta
    37441 cattacaaga aatagtgcaa caaaataatg atcttactat aaactatgaa ttattaaaac
    37501 aggaaggtcc tcctcacaga agaaagtttt ttactaatgt aaccatagat aatgaggtaa
    37561 gaggaacggg gataggatat agtaaaaaag aagcagaaca aaacgcagca aaggaagcat
    37621 taaagaattt aggtgataat tatgagtaaa ggtcattata taataccaat atttgtagct
    37681 caggaaggat gtccctacaa ttgtgttttt tgtaatcagc ataaaataac cggagaaaag
    37741 gacgaaataa tagacgaaaa ttacgtaaga gaaaccatag aagcttatat aaaaactata
    37801 gatagagaaa attcaacttt agaggtttct tttttcggag gtacttttac gggtatacct
    37861 atagaaaggc aaaagagtct tttaaaagta gcaaaggaat ataaggataa gggccaaata
    37921 gattgtatac atatgtccac aagaccagat tatatagaca gagaaatttt agataacctt
    37981 aaaaagtact ctgcggatat aattgaatta ggagttcaat ctttagatga agaagtcctt
    38041 ttaaaatcag gaagagggca ttccgtagaa gaggtgtata gagcctcaaa acttataaaa
    38101 gaatacggat ttactttagg acatcaaata atgttaggac ttccaggaga tacttttaaa
    38161 aaggacatag aaactgtaga aaaatcttta aagatgaaac cagatatagc aagaatatat
    38221 ccagccttgg taataaagga tactcctatg gaatatatgt taagaaaggg aacttataaa
    38281 ccttatactt tagatgaagc tatagatata actaaaatat tatattctat gtatgataaa
    38341 gaaggcataa aagtaataag aataggactt cagcctacag aagaaataaa tgaaaataaa
    38401 gatgtgattt caggtccttt tcatccagct tttagagaat tagtggaagg aaaaataatt
    38461 aatgaggcta ttttctccta tgtggaagat agtttagaag aaagcttaga aatttacata
    38521 aataataaag atatttctaa attgtattgt aatagaaaag aattctttaa tgaatttata
    38581 aataagaaga aagtaaaaag atttaaagtt atacaagatg aaacattagg tagagggaat
    38641 ataattatta aaaaggatga aaatcaagaa catatattta taaaagagta tatgagaaag
    38701 ctttcagaag aaggaaaaaa cttatttata tagaataata taagtatcaa gttaatataa
    38761 gctttagtgt ccccactgtt tcatattcag tggggatata tattttaagt tttaataatt
    38821 gatatttttt tttatatata ataaactatt aaatgatgtt atttttaaag ggaggtaaaa
    38881 ttgaaatgaa aagagaaaaa agagaaaaga tgactaaagt tttagttgtt gttatgacta
    38941 ttgtatttat tgctagtata ttaccaatgt tttttgccag ataggagttg tactacatgt
    39001 ttttaaaatc aattgaaata agaggtttta aatcttttgc agataaaact gaattaatgt
    39061 ttaaacaagg agtcacagca atagtaggtc ctaatgggag cgggaaaagt aatatatctg
    39121 acgcagtaaa atgggtgttg ggagaacaaa gtgtaaaatc cttaagggga agtaaaatgg
    39181 aggatgttat atttgctggt acacaatata gaaaaccagt aggactttgt caagtttcac
    39241 tgatattaga taacagtgat aaagacttac ccatagaata tacagaagta accataacta
    39301 gacgcttata tagatctggt gaaagtgagt attatataaa taatactcaa tgtaggctta
    39361 aagatataca agagttattt atggatacag gtataggtaa agaaggctat tctataatag
    39421 gacaagggaa aatagaggca gttttaagtg gaaagccaga ggagagaaga agtcttttag
    39481 aggaagcagc aggtatagtt aaatttaaat ggagaaaaga agaggcagat aaaaaacttt
    39541 ctaatacaga acaaaatctt ataagaataa aagatatatt aaatacttat gaagaaagaa
    39601 tagaaccact taaagaagaa agtgaaaaag ctaaaaagtt tttaaattta tcagaggaat
    39661 taaagcataa agaagtcaat attatgatat attctataga taagatagaa aaagacctag
    39721 aaaatataaa taacaatatg ctttctttaa gtgaaaatat agataactta aaaaatgaaa
    39781 aatcacagta caaagaaata attttaaagt ttaatgaaaa attagaactt ctagacacaa
    39841 ataatggtaa aaataaagaa gaatattatt ataataaaga taaaaataag gatatagaga
    39901 atgaaaatat tctattaaaa gaaaaaataa aaaatctaaa agataatata aaagtaaaag
    39961 aaaatacttt aaaaactaat gaagaaagat tacaaaatta tttaaaagaa aaggaagact
    40021 tagaaaaaaa attaaataaa ttaaaagaag aagaaattta tttaagagaa gagatagata
    40081 aaaaagaaga taacataaat aattttaata aagaactaaa ggaaaaagaa gataaactaa
    40141 agatgctaaa atctgaagag atagaaatac taagtaatac ggctaacctt agaaatgaaa
    40201 tatctgtaat ggaaaatgaa atagtaaatt tgaaaaataa attggataat ataaaaaatt
    40261 cctgtgatag ttatataagc tctataaata taaatataaa aactaaggaa gatatagaaa
    40321 aagaaataaa aaatataaaa gaaaatatac tttcattaga aaataattta aaagaaaaca
    40381 gtaaaaatat aggctcttta aaaatatccc ttaataataa agaaaaaaaa ttaaaggaga
    40441 aaaatgcagc ctacagtaga ttagaagcga attatcatat gctttcaaat ttagaaaagc
    40501 actatgaagg atataataga agtgtaaaaa ccttgatgga gcatgtaagt cagggcaaaa
    40561 tagataacat taatggaggc tgtgaagttt taggggatat aataaaagta aagaaagagt
    40621 ttgaaacagc catggagata gccttaggtg gagctatatc taatgttata acagaggatg
    40681 aaaacaaa
//