LOCUS       NZ_DS981517            33234 bp    DNA     linear   CON 30-MAR-2017
DEFINITION  Clostridium sporogenes ATCC 15579 Scfld_02_0, whole genome shotgun
            sequence.
ACCESSION   NZ_DS981517
VERSION     NZ_DS981517.1
KEYWORDS    .
SOURCE      Clostridium sporogenes ATCC 15579
  ORGANISM  Clostridium sporogenes ATCC 15579
            Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
            Clostridium.
COMMENT     REFSEQ INFORMATION: The reference sequence was derived from
            DS981517.
            Clostridium sporogenes (GenBank Accession Number for 16S rDNA gene:
            DQ911258*) is a member of the Firmicutes division of the domain
            bacteria and has been isolated from human feces. The sequenced
            strain was obtained from ATCC (ATCC 15579).
            We have collected 8.9X coverage in plasmid end reads and 454 reads.
            We have performed one round of automated sequence
            improvement(pre-finishing), along with manual improvement that
            includes breaking apart any mis-assembly, and making manual joins
            where possible. Manual edits also are made where the consensus
            appears to be incorrect. All low quality data on the ends of
            contigs is removed. Contigs are ordered and oriented where
            possible.
            Sequencing/Assembly: The genomic DNA was purified from liquid
            culture derived from a single bacterial colony. A hybrid sequencing
            strategy that utilized reads from both 454 GS-20 and ABI 3730xl
            sequencers was devised and implemented to generate the draft genome
            sequences. 454 reads were assembled using Newbler (454 Life
            Sciences) into 454 de novo contigs.These de novo contigs were
            converted in silico to 800 base paired reads ('superreads') with
            400 base overlaps with neighboring superreads. Finally, PCAP
            (Huang, et al, Genome Research, 13:2164, (2003)) was used to
            assemble the super-reads and the conventional 3730xl capillary
            reads.
            This sequenced strain is part of a comprehensive, sequence-based
            survey of members of the normal human gutmicrobiota.  A joint
            effort of the WU-GSC and the Center for Genome Sciences at
            Washington University School of Medicine, the purpose of this
            survey is to provide the general scientific community with a broad
            view of the gene content of 100 representativesof the major
            divisions represented in the intestine's microbial community. This
            information should provide a frame of reference for analyzing
            metagenomic studies of the human gut microbiome. Further details of
            this effort are described in a white paper entitled 'Extending Our
            View of Self: the Human Gut Microbiome Initiative (HGMI)'
            (http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMIS
            eq.pdf). These studies are supported by National Human Genome
            Research Institute.
            Coding sequences were predicted using GeneMark v3.3 and Glimmer2
            v2.13. Intergenic regions not spanned by GeneMark and Glimmer2 were
            blasted against NCBI's non-redundant (NR)  database and predictions
            generated based on protein alignments. tRNA genes were determined
            using tRNAscan-SE 1.23 and non-coding RNA genes by RNAmmer-1.2 and
            Rfam v8.0. Gene names are generated at the contig level and may not
            necessarily reflect any known order or orientation between contigs.
            For answers to your questions regarding this assembly or project,
            or any other GSC genome project, please visit our Genome Groups web
            page (http://genome.wustl.edu/genome_group_index.cgi) and email the
            designated contact person.
            Annotation was added to the contigs in May 2008.
            This is a reference genome for the Human Microbiome Project. This
            project is co-owned with the Human Microbiome Project DACC.
            Product names were updated in August 2012.
            Clostridium sporogenes (GenBank Accession Number for 16S rDNA gene:
            DQ911258*) is a member of the Firmicutes division of the domain
            bacteria and has been isolated from human feces. The sequenced
            strain was obtained from ATCC (ATCC 15579).
            We have collected 8.9X coverage in plasmid end reads and 454 reads.
            We have performed one round of automated sequence
            improvement(pre-finishing), along with manual improvement that
            includes breaking apart any mis-assembly, and making manual joins
            where possible. Manual edits also are made where the consensus
            appears to be incorrect. All low quality data on the ends of
            contigs is removed. Contigs are ordered and oriented where
            possible.
            Sequencing/Assembly: The genomic DNA was purified from liquid
            culture derived from a single bacterial colony. A hybrid sequencing
            strategy that utilized reads from both 454 GS-20 and ABI 3730xl
            sequencers was devised and implemented to generate the draft genome
            sequences. 454 reads were assembled using Newbler (454 Life
            Sciences) into 454 de novo contigs.These de novo contigs were
            converted in silico to 800 base paired reads ('superreads') with
            400 base overlaps with neighboring superreads. Finally, PCAP
            (Huang, et al, Genome Research, 13:2164, (2003)) was used to
            assemble the super-reads and the conventional 3730xl capillary
            reads.
            This sequenced strain is part of a comprehensive, sequence-based
            survey of members of the normal human gutmicrobiota.  A joint
            effort of the WU-GSC and the Center for Genome Sciences at
            Washington University School of Medicine, the purpose of this
            survey is to provide the general scientific community with a broad
            view of the gene content of 100 representativesof the major
            divisions represented in the intestine's microbial community. This
            information should provide a frame of reference for analyzing
            metagenomic studies of the human gut microbiome. Further details of
            this effort are described in a white paper entitled 'Extending Our
            View of Self: the Human Gut Microbiome Initiative (HGMI)'
            (http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMIS
            eq.pdf). These studies are supported by National Human Genome
            Research Institute.
            For answers to your questions regarding this assembly or project,
            or any other GSC genome project, please visit our Genome Groups web
            page (http://genome.wustl.edu/genome_group_index.cgi) and email the
            designated contact person.
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline
            set; GeneMarkS+
            repeat_region
            ##antiSMASH-Data-START##
            Version      :: 5.0.0alpha
            Run date     :: 2018-12-14 14:15:44
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1581971
            Orig. end    :: 1615205
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     cluster         1..33234
                     /aStool="rule-based-clusters"
                     /cluster_number="6"
                     /contig_edge="False"
                     /core_location="[1591971:1605205]"
                     /cutoff="20000"
                     /detection_rule="(minimum(8, [Aldedh_7_tma, BMC, Fer4_12,
                     Fer4_14, Fer4_16, Fer4_21, Fer4_7, Fer4_9, Gly_8-9_TMA,
                     PFL-like, PduV-EutP, RSAM_130_tma]) and PFL-like and
                     Gly_8-9_TMA and Aldedh_7_tma)"
                     /neighbourhood="10000"
                     /parent_cluster_number="6"
                     /product="TMA"
                     /tool="antismash"
     cluster_core    10001..23234
                     /aStool="rule-based-clusters"
                     /cluster_number="6"
                     /cutoff="20000"
                     /detection_rule="(minimum(8, [Aldedh_7_tma, BMC, Fer4_12,
                     Fer4_14, Fer4_16, Fer4_21, Fer4_7, Fer4_9, Gly_8-9_TMA,
                     PFL-like, PduV-EutP, RSAM_130_tma]) and PFL-like and
                     Gly_8-9_TMA and Aldedh_7_tma)"
                     /neighbourhood="10000"
                     /parent_cluster_number="6"
                     /product="TMA"
     supercluster    1..33234
                     /child_cluster="6"
                     /contig_edge="False"
                     /detection_rules="(minimum(8, [Aldedh_7_tma, BMC, Fer4_12,
                     Fer4_14, Fer4_16, Fer4_21, Fer4_7, Fer4_9, Gly_8-9_TMA,
                     PFL-like, PduV-EutP, RSAM_130_tma]) and PFL-like and
                     Gly_8-9_TMA and Aldedh_7_tma)"
                     /kind="single"
                     /product="TMA"
                     /supercluster_number="6"
                     /tool="antismash"
     region          1..33234
                     /contig_edge="False"
                     /product="TMA"
                     /rules="(minimum(8, [Aldedh_7_tma, BMC, Fer4_12, Fer4_14,
                     Fer4_16, Fer4_21, Fer4_7, Fer4_9, Gly_8-9_TMA, PFL-like,
                     PduV-EutP, RSAM_130_tma]) and PFL-like and Gly_8-9_TMA and
                     Aldedh_7_tma)"
                     /supercluster_numbers="6"
                     /tool="antismash"
     gene            1276..1503
                     /locus_tag="CLOSPO_RS07575"
                     /old_locus_tag="CLOSPO_02852"
     CDS             1276..1503
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003485384.1"
                     /locus_tag="CLOSPO_RS07575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02852"
                     /product="DUF1963 domain-containing protein"
                     /protein_id="WP_003485384.1"
                     /transl_table=11
                     /translation="MPWESKLGGYPAFTQCDPRYYDKNLERFNTLLLQLDCEDECDVMF
                     GDAGVANFFINEEDLKKLDFTKVLYNWDCC"
     gene            1802..2332
                     /locus_tag="CLOSPO_RS07580"
                     /old_locus_tag="CLOSPO_02853"
     CDS             1802..2332
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254625.1"
                     /locus_tag="CLOSPO_RS07580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02853"
                     /product="acetylglutamate kinase"
                     /protein_id="WP_080544109.1"
                     /transl_table=11
                     /translation="MSLRDTMRMLWEQHSVWTRLAIMSIVAGSPNEDLVVARLLRNPKD
                     FEEALRPFYGDEVAAEFNKLLTSHLVIASEIVKASKAGNTDAAADAEKRWYENADKIAE
                     LLSKINPYWYFEDWQAMLHEHLALVKAEAVAILTSDYEKGISIYDDIEMQALEMADMMA
                     DGIVKQFPERFQD"
     gene            complement(2574..3473)
                     /locus_tag="CLOSPO_RS07585"
                     /old_locus_tag="CLOSPO_02854"
     CDS             complement(2574..3473)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012704769.1"
                     /locus_tag="CLOSPO_RS07585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02854"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_042384839.1"
                     /transl_table=11
                     /translation="MNKAEIVRKELRLIIRELGLLNYNCLNSGLTLVQAHVLNYLKQNG
                     ITPFNELTIQLGIDKASLSRILNSLKAKNFIKIEKSPNDKRIKHISLLSSGLESMINGD
                     MEANKFINEILDLGNDTVNDNISKSLKEFRILALKNNLIKDGSRIKIERLSSNYLDDAI
                     RLTTEIFAYEQNIPKELIPINKDLKQIWWCARVGEDIIGVVACWQENNQWHWGRFAVDK
                     RLRGLGIGKKMAIFSLNEMFNLNVEKVFIDARDVTVIILKQLGCEVLGNPIDFYGEPVT
                     PVVITKQDFINKIKHQTK"
     gene            <3587..3813
                     /locus_tag="CLOSPO_RS19260"
                     /pseudo=""
     CDS             <3587..3813
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003358494.1"
                     /locus_tag="CLOSPO_RS19260"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing start; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="FFSLRTENSNEAAQLSGMAQSLGYLLAAFDPILFGFLHDATNS"
     gene            complement(3934..5235)
                     /locus_tag="CLOSPO_RS07590"
                     /old_locus_tag="CLOSPO_02856"
     CDS             complement(3934..5235)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254623.1"
                     /locus_tag="CLOSPO_RS07590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02856"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_042384841.1"
                     /transl_table=11
                     /translation="MSIKNTFIRYILTNIIGMIGLSCYILADTFFISKGLGVQGLTALN
                     LSISIYSFINATGLLIGIGGATKYSIYQARNKHNKANIVFTNSIKIGILLGIFFLLIGL
                     FGSSTLSSLLGADENIFRMTNTYLKTLLCFAPFFILNNIFIAFIRNDGNPKLSMAGMLI
                     GSLSNIILDYVFIFPLQWGMFGAAFATGLAPIISMCILTRHYIKKKNHFHFHKSKLSIK
                     QITYICSLGISSFITEIASGVILIVFNLLILNISGNIGVAAYGIVANLALVATSIFTGI
                     AQGTQPLLSENFGQGNNKKILQLFKYAIYASLVVSIVLYFLVVIFNNQLVEIFNRDHIK
                     ILSKTASNGLIIYFAGFFFAGINIITSAVLSSINEPRHAFTISILRSGCIIVPVALFLS
                     YFFQMTGIWLSFPLSEIITLIIAVFLAKKSLKRL"
     gene            5759..6901
                     /locus_tag="CLOSPO_RS07595"
                     /old_locus_tag="CLOSPO_02857"
     CDS             5759..6901
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012343158.1"
                     /locus_tag="CLOSPO_RS07595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02857"
                     /product="alcohol dehydrogenase"
                     /protein_id="WP_042384844.1"
                     /transl_table=11
                     /translation="MKEFSINTDVYFGEGSLDRLKEIKNKRVLIVCDKFMETSGMAAKV
                     QQKLVDCEVAIYSDIVPDPSVEVIASGIQKLQSCNAEIMIALGGGSSIDGAKAMREYAK
                     KITGGVSTIEEFYAIPTTSGTGSEVTEYAVITNKQEGLKYALTDKSLLPTVAILDPELV
                     KSVPKAITADTGMDVITHAMEAYVSKNATDFSDALAEKAFTLAFRFLPQAYADGNDIIA
                     REKLHNASCLAGMAFNAAGLGITHSLAHAVGGKLHISHGRSNAIILPYVVEYNASLNKE
                     TFNVEYDVAAKKYQRLAKLLKLHAPNVNIGVNNLIKSIVELQNTLMIPATLKEQGADMA
                     LAEASREEIINAALKDVCTTANPREATKEDLSKILEKVLG"
     gene            7005..7835
                     /locus_tag="CLOSPO_RS07600"
                     /old_locus_tag="CLOSPO_02858"
     CDS             7005..7835
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254621.1"
                     /locus_tag="CLOSPO_RS07600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02858"
                     /product="MerR family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_003485397.1"
                     /transl_table=11
                     /translation="MEDELYSIGKVGKICKITKKALRYYDKMDILSPDKVADESGYRYY
                     SKNTLLSVPVIKYYKQSGFKLEEMKGFLEGKTYDFFHTSFRNKIDELKELEKEINLKLR
                     SVKDWDDLIVEAQMVIENNVSDVAIKYIDNRTLTFLDQDFEYDYMDSIINIEFTNYIDS
                     IDNAITGPVIIRFPCFQDKMNGKCNKMRIMQETILKCKEELSVEFGGWMVAACYHIGPH
                     ETISETYKKIKDWTEKHGYICSEESYERYVTDYWTTKNRNRFVTEVLIKISREK"
     gene            8321..9433
                     /locus_tag="CLOSPO_RS07605"
                     /old_locus_tag="CLOSPO_02859"
     CDS             8321..9433
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254620.1"
                     /locus_tag="CLOSPO_RS07605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02859"
                     /product="membrane protein"
                     /protein_id="WP_003402123.1"
                     /transl_table=11
                     /translation="MNGDSKAVSLEAVAAKKKLSSDFFKKGISLALFSGLAYGLYTAFL
                     TMGMTKGVWGDWYGPNTAGLSAFAIAYLLAALGNAINDTCSAVWALLYAGVKGKFGDFL
                     RCINTKPGRIMILAALIGGPIAGTAYVIALQMAGSIVVPISALCPAIAAILGKILYKQE
                     LNKRMAFGILICVCASFLIGSTGLSGGASANTLIGIAIAIIAALGWGFEGCVAGYGTAM
                     IDPEIGICIRQVTSGIANLFILVPIFGMMAGGIGISTDLAVKAFTSSPAMVWFALSGLL
                     SFVTFMTWYAGNSMCGAGLGTACNGTYSFFGPLFCLLVLGVYGGMDGWSLPPVAWIGAV
                     IMMFGILTISMNPLDLFKGKKMEVDIDETA"
     gene            9420..9686
                     /locus_tag="CLOSPO_RS07610"
                     /old_locus_tag="CLOSPO_02860"
     CDS             9420..9686
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254619.1"
                     /locus_tag="CLOSPO_RS07610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02860"
                     /product="hypothetical protein"
                     /protein_id="WP_003485400.1"
                     /transl_table=11
                     /translation="MKPLNYAILKYFTKVSEACADDVIKALKGQYGSFKALNKKAVINA
                     LLTAEANGLIEETRFDLDNNNELRVYYHAHAEGAETINKYIPD"
     gene            10001..10297
                     /locus_tag="CLOSPO_RS07615"
                     /old_locus_tag="CLOSPO_02861"
     CDS             10001..10297
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) TMA:
                     BMC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254617.1"
                     /locus_tag="CLOSPO_RS07615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02861"
                     /product="microcompartment protein"
                     /protein_id="WP_003358244.1"
                     /sec_met_domain="BMC (E-value: 1.6e-28, bitscore: 95.7,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRYYGDEALGLVETIGLVPALEAADKMLKAANVELISYENIGSTL
                     VTIMVKGDVGAVKSAVEAGAEAARAIGKLTAHNVMPRPIREVGDIVSVHDIDS"
     gene            10321..10629
                     /locus_tag="CLOSPO_RS07620"
                     /old_locus_tag="CLOSPO_02862"
     CDS             10321..10629
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) TMA:
                     BMC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254616.1"
                     /locus_tag="CLOSPO_RS07620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02862"
                     /product="BMC domain-containing protein"
                     /protein_id="WP_003485402.1"
                     /sec_met_domain="BMC (E-value: 2.8e-27, bitscore: 91.7,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARYEALGLIETFGLVFALEAADAMCKSADVELIGYENVASGYIS
                     VLVRGDVGACKTAVDAGVAAVNGMEGGSLYSSIVIPRPHEDLEKIIKRYAIPDLITE"
     gene            10667..12148
                     /locus_tag="CLOSPO_RS07625"
                     /old_locus_tag="CLOSPO_02863"
     CDS             10667..12148
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) TMA:
                     Aldedh_7_tma"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254615.1"
                     /locus_tag="CLOSPO_RS07625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02863"
                     /product="acetaldehyde dehydrogenase"
                     /protein_id="WP_003485404.1"
                     /sec_met_domain="Aldedh_7_tma (E-value: 3.6e-79, bitscore:
                     263.3, seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIIDNDLLSMQEARILVENAREAQKKLATFPQEKLDEIVERMAE
                     EVEKHLKELAKISNEETEYGKWQDKYVKNHFVCEYLKNKLKGMRCVGIINEDKINKTMD
                     VGVPMGVVIAFPPATSPVSTTIYKALIAIKSGNAIIFSPHKRAKNTISKTVDILIKAAE
                     GVGLPEGALAYLHTVTESGSLELMKHKDTSLIMNTGVIEMLDEAYRSGKPVIYGGNGNG
                     PAFIERTADIEKAVKDIITSKNFDYGVVSAAEQSIVVDSLIASEVKQELIKNGGYFMTE
                     EEALKLGKILFNQNGTPDLEMIGKSPQFLAKKAGFQVSEGIKVLISNEKFVSKNNPYSR
                     EKLCPVLAFYIEDDWMHACEKCIELLLTERYGHTLVIHSKDEEVIRQFALKKPVGRVLV
                     NTAGTFGSMGATTNLFPSMTLGSGSAGQGMTSDNVSPMNLLYIRKVGYGVRMVDEIVKT
                     VNDKEDSISAISNGNEIDNYKLLESILKKVLQDLK"
     gene            12198..14738
                     /locus_tag="CLOSPO_RS07630"
                     /old_locus_tag="CLOSPO_02864"
     CDS             12198..14738
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) TMA:
                     Gly_8-9_TMA"
                     /gene_functions="biosynthetic (rule-based-clusters) TMA:
                     PFL-like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254614.1"
                     /locus_tag="CLOSPO_RS07630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02864"
                     /product="choline trimethylamine-lyase"
                     /protein_id="WP_042384851.1"
                     /sec_met_domain="Gly_8-9_TMA (E-value: 5e-62, bitscore:
                     204.2, seeds: 275, tool: rule-based-clusters)"
                     /sec_met_domain="PFL-like (E-value: 2.7e-231, bitscore:
                     766.9, seeds: 123, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIREFSNKFMEATKNMSDEERAGLMKMFQSVSNEITKEEPATSK
                     VACDNNGEIPDGMTERLVKLKENYMKHVPSITTHRARAITKIAKENPGIPKSVLRGKCF
                     KHCCETAPLLIQDHELIVGAPNGKPRAGAFSPDIAWRWMVDEIDTIGTRPQDPFYISEE
                     DKKIMREELFPYWAGKSVDEYCEDQYREAGVWELSGESFVSDCSYHAVNGGGDSNPGYD
                     VVLMKKGMLDIKREAEEKLAELKYENPEDIDKIYFYKSLIDTAEGVMIYAKRMSDYAAE
                     LAQKETNPKRKAELQKISEINARVPAHKPSTYWEAIQAVWTIESLLVVEENQTGMSIGR
                     VDQYMYPFYKADIEAGRMTDYEAFELSGCMLIKMSEMMWITSEGGSKFFAGYQPFVNMC
                     LGGVTREGRDATNELTYLLMDAVRHVKIYQPSLACRIHKGSPQKYLKKIVDVIRAGMGF
                     PACHFDDVHIKIMLAKGVSIEDARDYCLMGCVEPQKSGRLYQWTSTGYTQWPICIELVL
                     NHGVPLWYGKQVCPDMGDLSQFKTYEQFEAAVKEQIKFITKWTSVATVISQRVHKELAP
                     KPLMSMMYEGCMENGKGVEAGGAMYNFGPGVVWSGLATYTDSMAAIKKLVFEDKKYTLQ
                     EMNEALKADFVGYEQLKKDCLEAPKYGNDDDYADLIAADLINFTEQEHRKYKTLYSVLS
                     HGTLSISNNTPFGQMTGATANGRRAWMPLSDGISPSQGADFKGPTSIIKSVSKMSCEDM
                     NIGMVHNFKLISGLLDTPEGEQGIITLLRSACALQLGEVQFNYLDNKTLIEAQKHPDQY
                     RDLIVRVAGYSAFFVELCKDVQDEIISRTMLTHF"
     gene            14920..15873
                     /locus_tag="CLOSPO_RS07635"
                     /old_locus_tag="CLOSPO_02865"
     CDS             14920..15873
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) TMA:
                     RSAM_130_tma"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001387906.1"
                     /locus_tag="CLOSPO_RS07635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02865"
                     /product="choline TMA-lyase-activating enzyme"
                     /protein_id="WP_003494063.1"
                     /sec_met_domain="Fer4 (E-value: 1.7e-06, bitscore: 24.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="RSAM_130_tma (E-value: 1.6e-110, bitscore:
                     364.9, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNGNLGIIERKARIFNIQKYNMYDGDGIRTLVFFQGCPLRCKWC
                     ANPEGLEKKYRVMLKSNLCVNCGACVSACPVGIHTISNKTLKHEVNRDIDCIGCGKCKE
                     ACLKSAISIVGEEKTISELLKIVEEDRTFYEMSGGGVTLGGGEVLMQPEAATSLLMACK
                     QEGINTAIETCGYTKLETILKVAEFVDLFLFDIKNINSDRHYELTGVRNERILENLQEL
                     LKKKYNVKIRMPLLKGINDSQDEIEKTMEFLLPYKDYKNFKGIDLLPYHKMGVNKYNQL
                     GMEYPIKDDPSLKNEDLDRIESWIKKYDLPVKVIRH"
     gene            15913..16266
                     /locus_tag="CLOSPO_RS07640"
                     /old_locus_tag="CLOSPO_02866"
     CDS             15913..16266
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) TMA:
                     BMC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254612.1"
                     /locus_tag="CLOSPO_RS07640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02866"
                     /product="propanediol utilization protein PduU"
                     /protein_id="WP_003485409.1"
                     /sec_met_domain="BMC (E-value: 1.4e-15, bitscore: 54.3,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFSDRNIQRVIQESVPGKQITIAHVIASPMPDIYDRLGIDEKG
                     AIGILTLSPFETAIIAADIATKASDVEIGFLDRFTGSVVISGDIQSVETALSAVNDTLK
                     DMLGFTTAPITRT"
     gene            16263..16709
                     /locus_tag="CLOSPO_RS07645"
                     /old_locus_tag="CLOSPO_02867"
     CDS             16263..16709
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) TMA:
                     PduV-EutP"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001387904.1"
                     /locus_tag="CLOSPO_RS07645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02867"
                     /product="hypothetical protein"
                     /protein_id="WP_003485412.1"
                     /sec_met_domain="PduV-EutP (E-value: 7.2e-32, bitscore:
                     107.3, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKKRIMVIGPSKCGKTTLVNALNDYDGPLRRTPDLIYGKNTIDV
                     PGSYIENAWMYKHIIAAAQDASCVLILVDQSNCTEIYSHGFAKSFRCPVIGVIAKCDLM
                     PKNKEKCEMQLKKIGVSEPYFHISFEMGTGIDALKKYLFEKGEE"
     gene            16716..17444
                     /locus_tag="CLOSPO_RS07650"
                     /old_locus_tag="CLOSPO_02868"
     CDS             16716..17444
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254610.1"
                     /locus_tag="CLOSPO_RS07650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02868"
                     /product="hypothetical protein"
                     /protein_id="WP_003485414.1"
                     /transl_table=11
                     /translation="MMKFITEEYLRDLYRKEPFNTYKLEQGQRLTPGAAEYLSDKGIKL
                     SDDLKVNKSSKINANISPKNSAKTPEETSKEIMKDVGNSDVNFNLNKKLCLRLKSMEAK
                     FLVVSSEILKEDIILAQNIINLGRKISNIRNVLDGKGTLEPIYLKECTGMNSSNSEADL
                     DDCFEITEFHMQFPKSNAILKMNVLRCAVQELQLEIIDTYKSDDESLKSKIMDNVNLII
                     NSLSQLICLAVGGKECQRKN"
     gene            17426..18271
                     /locus_tag="CLOSPO_RS07655"
                     /old_locus_tag="CLOSPO_02869"
     CDS             17426..18271
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254609.1"
                     /locus_tag="CLOSPO_RS07655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02869"
                     /product="ethanolamine utilization protein EutJ"
                     /protein_id="WP_003485417.1"
                     /transl_table=11
                     /translation="MSEEKLTFEYCDNMVRKFEEVIEKPIVNGSSVYYTGVDLGTACVV
                     LAVLDENYNPVAGAYRYADVVRDGMVVDYIGAVRIVRELKEEIEEKLNTELIYAAAAIP
                     PGTDALDSGAIKNVVQSAGFELTCLLDEPTAANAVLKIQNGAVVDIGGGTTGISILKDG
                     KVVYVVDEPTGGTHFSLVISGAYEMPFNKADEYKRDNKNHKEILPVLKPVVEKVSSIIN
                     NHIKNYDVNEISLVGGTCCLTGIEEIIEKQTGVYTHKPRNPMFVTPLGIALSCTRDIIE
                     "
     gene            18349..18645
                     /locus_tag="CLOSPO_RS07660"
                     /old_locus_tag="CLOSPO_02870"
     CDS             18349..18645
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) TMA:
                     BMC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254608.1"
                     /locus_tag="CLOSPO_RS07660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02870"
                     /product="BMC domain-containing protein"
                     /protein_id="WP_003485418.1"
                     /sec_met_domain="BMC (E-value: 1.9e-07, bitscore: 28.2,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFRIIKSPSSSTKDILRRRMGGNCKADLESADAIGLVQGKLIDM
                     IYAADIAEKAVGVTVEDIRGTCPQHMVLLGIFGDTSSVEAALNEIKLKMKEVK"
     gene            18648..18911
                     /locus_tag="CLOSPO_RS07665"
                     /old_locus_tag="CLOSPO_02871"
     CDS             18648..18911
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254607.1"
                     /locus_tag="CLOSPO_RS07665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02871"
                     /product="ethanolamine utilization protein EutN"
                     /protein_id="WP_003361873.1"
                     /transl_table=11
                     /translation="MIAARLIDNVWATRKAESLSGLKFMLAEEIGGIDEGRRFIVVDII
                     SAGIGDRVIVSTGSSARRMLGDDNIPVDAVVIGIIDEDCNFG"
     gene            19110..19772
                     /locus_tag="CLOSPO_RS07670"
                     /old_locus_tag="CLOSPO_02872"
     CDS             19110..19772
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254606.1"
                     /locus_tag="CLOSPO_RS07670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02872"
                     /product="DUF861 domain-containing protein"
                     /protein_id="WP_040108438.1"
                     /transl_table=11
                     /translation="MKKLIAAKDIEALILKGEKVLYVDGTEIITPSAKDLVKNNGIVIT
                     TEAPAPKVEHLIGKNVPNIEGIDSEMMLKFLRAMMDKGLLQEMLQCLKGKDLPFKAECD
                     PNGLKVVRGNSVKMDVFDTGNPNAKVQFQELVSKEESKMSAGFLIIENSKFDWELTYEE
                     IDYVIEGTLTVEINGKTYTAYPGDVLFVPSGSKVVWGSPDKARVFYTTYPANWADLL"
     gene            19793..20587
                     /locus_tag="CLOSPO_RS07675"
                     /old_locus_tag="CLOSPO_02873"
     CDS             19793..20587
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) TMA:
                     BMC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254605.1"
                     /locus_tag="CLOSPO_RS07675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02873"
                     /product="BMC domain-containing protein"
                     /protein_id="WP_003485423.1"
                     /sec_met_domain="BMC (E-value: 9.2e-26, bitscore: 86.9,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQALGLIETKGLLAAVEAADTMVKSADVSIIEKTYVGGGLVTISV
                     TGDVGAVKASIEAGVAAVKKLDEGFLVSEHVIPRPHEELESIIGPNTPPEDPSSNDNTE
                     NVEDADDTEAVEKAEDTEKVENTKAVDSVEDTESVEVTKDIVDVKNVENTKKAETVKAV
                     DNTEPVDVDTKNNIKENQHGLDGDLDKLHKLNLENLNKEDVDNLIRKNGIEKTILILAK
                     LKVVKLRNLAREYKDFGIAGRTISKAGKNLLINKFKLYYEKN"
     gene            20622..22220
                     /locus_tag="CLOSPO_RS07680"
                     /old_locus_tag="CLOSPO_02874"
     CDS             20622..22220
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) TMA:
                     Aldedh_7_tma"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254604.1"
                     /locus_tag="CLOSPO_RS07680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02874"
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="WP_003485425.1"
                     /sec_met_domain="Aldedh_7_tma (E-value: 8e-163, bitscore:
                     537.6, seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENFDKDLRSIQQARDLARLGKVAADKIADYTEEQIDKILRNMVR
                     VAEENAVCLAQMAVEETGFGKVEDKTFKNHLAATILYNSIKDMKTIGVINEDKENKLIE
                     LAEPVGLVMGIVPSTNPTSTAIFKAMISIKSRNAIVFAPHPAAAKCTIKAVELMRDAAI
                     EAGAPENIISAVTIPTIGATNELMKSKEVAIIIATGGPGMVKAAYSSGTPAIGVGAGNS
                     PAYIERTADVEKAVKNIIASKTFDNGTICASEQSIICEECNHDLVVAEFKKQGGYFMTE
                     EETEKVCRLLFKKGNAMNAKFVGRSPQVIASAAGFTIPAGTKVLIGRQNGVGEGYPLSF
                     EKLTTVLGFYTVKDWHEACELSIELLQNGIGHTMSIHTEDRDMVMKFARKPASRILVNT
                     GGTQGGTGASTGLNPSFTLGCGTWGGSSVSENVTPKHLMNIKRVAYGIKDCTNLASNDP
                     TFNCIKTAENCHGVQNQFMNMSPAQIAAAAEVLNKANNCAENTNTCTECSSENTKNEEL
                     LDLVNQIVAAMKGAN"
     gene            22220..22870
                     /locus_tag="CLOSPO_RS07685"
                     /old_locus_tag="CLOSPO_02875"
     CDS             22220..22870
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTAC"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254603.1"
                     /locus_tag="CLOSPO_RS07685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02875"
                     /product="phosphate propanoyltransferase"
                     /protein_id="WP_003485428.1"
                     /sec_met_domain="PTAC (E-value: 6e-29, bitscore: 97.3,
                     seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNCEEVLKLLLEAVKSKELNNAVNRNSSEIPVGISNRHIHLSQK
                     DLDILFGENYGLTKIKDLSQPGQYACKEVVTICGPKGAIEKIRILGPVRSKTQVEVLAG
                     DCIKLGSVSHVKLSGDLNRTAPITIVGPKGSVQLEEGLIVAQRHIHMTPEDAKNLGVHD
                     GEIVSIKFEDLRGGIYNNVAVRANDASSLECHLDIEEANAMGINSKSKVTIVK"
     gene            22944..23234
                     /locus_tag="CLOSPO_RS07690"
                     /old_locus_tag="CLOSPO_02876"
     CDS             22944..23234
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) TMA:
                     BMC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254602.1"
                     /locus_tag="CLOSPO_RS07690"
                     /note="ethanolamine utilization protein; involved in the
                     degredation of ethanolamine; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="CLOSPO_02876"
                     /product="ethanolamine utilization microcompartment protein
                     EutM"
                     /protein_id="WP_003358305.1"
                     /sec_met_domain="BMC (E-value: 1.1e-28, bitscore: 96.2,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYDALGMIETKGLVGSIEAADAMVKAANVYLIGKEYVGGGLVTV
                     MVRGDVGAVKAATDAGAAAAQRVGELVSVHVIPRPHSEVEVILPSSKEVAK"
     gene            23516..23908
                     /locus_tag="CLOSPO_RS07695"
                     /old_locus_tag="CLOSPO_02877"
     CDS             23516..23908
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003485430.1"
                     /locus_tag="CLOSPO_RS07695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02877"
                     /product="hemerythrin"
                     /protein_id="WP_003485430.1"
                     /transl_table=11
                     /translation="MFEMKDEYRLGIPSIDEEHEKLFEIGERAYKLLKDPYTIDKYDKI
                     VDVISELKDYTAYHFKNEEEYMQSINYKRLFTQKIEHEGFIKRLNELDLDKIDENQDEY
                     IMDVLKFLNNWIINHIVEKDLLIVSK"
     gene            24153..24419
                     /locus_tag="CLOSPO_RS07700"
                     /old_locus_tag="CLOSPO_02878"
     CDS             24153..24419
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS+"
                     /locus_tag="CLOSPO_RS07700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS+."
                     /old_locus_tag="CLOSPO_02878"
                     /product="hypothetical protein"
                     /protein_id="WP_003485433.1"
                     /transl_table=11
                     /translation="MFSIEYLINIIKMFLPPRAEIITIDKPYKTPAVGMVDLDGNGILE
                     LIAAYKWQGENYIIVLKYYCGTWYMADTVKGIQYNIFRCCSSY"
     gene            24442..24954
                     /locus_tag="CLOSPO_RS07705"
                     /old_locus_tag="CLOSPO_02879"
     CDS             24442..24954
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS+"
                     /locus_tag="CLOSPO_RS07705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS+."
                     /old_locus_tag="CLOSPO_02879"
                     /product="hypothetical protein"
                     /protein_id="WP_003485435.1"
                     /transl_table=11
                     /translation="MGWQVGAIWSDLSVYEWTDMGLEDLINGNKYFSLIEVKDIKGIQG
                     KDGIYELALWIHDTGKAYKVEIYRWSGDKFTLALDVYPYYFKKVANYYKKLLKEMDSTV
                     YWYYLADAQIKTGDIQGALESIDRALDSEYPYPSKEELIDLKAQICQYTPFSMVQHIQV
                     TLPLSLK"
     gene            25335..26921
                     /locus_tag="CLOSPO_RS07710"
                     /old_locus_tag="CLOSPO_02880"
     CDS             25335..26921
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254676.1"
                     /locus_tag="CLOSPO_RS07710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02880"
                     /product="hypothetical protein"
                     /protein_id="WP_003485436.1"
                     /transl_table=11
                     /translation="MQKRFNVTGTCIPEKHYMVDISNKLDSILKLVNNEEYFIINRPRQ
                     YGKTTTLYMLEKRLNRMEEYLPIKISFEAIDTEGYSEVKKFLSSIMMQIVNYFRFSTNK
                     EIYKFVKNHENKITTMNEFNSFITDLIEFAEKKVVLIIDEVDKSSNNQLFLDFLGMLRS
                     KYLLRNEGRDYTFHSVILAGVHDIKTLKLKIRSNEEHKYNSPWNIASDFDVEMSFSIEE
                     IKTMLDDYVENKKVDLDKEYFSEKLYFYTSGYPFLVSKLCKIIDEKIMDQNELKWEKEY
                     LELAVKELLNESNTNFDSLIKNIENNKELSELVDNLLIKGIQLNFNIHNPDINLGYLYG
                     IFRNEKGNLKINNRIYEQLIYNYRISKIQTSSNFVNYNSKENFIDSNGDLNIKKVLLKF
                     QEFMKHEYSRKREAFLEEDGRLVFLAFLSPIINGSGFAFKEVKGGEEKRFDIVITYNKK
                     MYILELKIWRGEEYHKKGLIQLGEYLNQYGLDEGYLLIFDFRKAASLIGIVEETYVDIE
                     EHRKKIIEVYC"
     gene            27158..28237
                     /locus_tag="CLOSPO_RS07715"
                     /old_locus_tag="CLOSPO_02881"
     CDS             27158..28237
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003485438.1"
                     /locus_tag="CLOSPO_RS07715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02881"
                     /product="hypothetical protein"
                     /protein_id="WP_003485438.1"
                     /transl_table=11
                     /translation="MKKKIGLIMSMLLLFVFVFSYTKNDYAVYAQNNETKVGQQLLQSE
                     EGWKRIEEDNNNFSYINGKYTSWIRYSDINYSGGYSMVPNDIDNSKVNGYLLKVKFNTV
                     TDKIRIIMFSRYYCTNNIEIKIDGIPYIFEARSYNQAKPTVCFEKKDLAYKEHTVEITN
                     LLDSNINSAMYFDAVDIDKNGQLKPYKEAAKVESISLDKTSMDLLEGSSDKLNAKVLPE
                     DATNKKVVWSSSDEKIVTVDKDGKVTAMKEGQATITAKVEGTDLTATCKVNVTKKVEEN
                     KNNAILSISLVNGATKEYDVNMQEVEKFINWFEERSNGKGSSLYSFNKKINPYKTVKEY
                     IVHDKIASFEVREYEGTNK"
     gene            28331..28530
                     /locus_tag="CLOSPO_RS07720"
                     /pseudo=""
     CDS             28331..28530
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012099734.1"
                     /locus_tag="CLOSPO_RS07720"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGGERLKVGKY"
     gene            28686..29876
                     /locus_tag="CLOSPO_RS07725"
                     /old_locus_tag="CLOSPO_02882"
     CDS             28686..29876
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003485440.1"
                     /locus_tag="CLOSPO_RS07725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02882"
                     /product="glycoside hydrolase"
                     /protein_id="WP_003485440.1"
                     /transl_table=11
                     /translation="MEGVNMKKYKYLKSVLMSFFIFTIFFICSEVKVQAMTNTDPQLGS
                     ALKEVQVGEQVKAIDSRYGWWLIAENGKLAWCNAGPTSYWDKNTGNFPILLRINQKMNI
                     HEAQVVYNYKKGQIIQVINGSVTGWWKVKTPDGYYGWVNSANTSRNSSGKLIASSNVSA
                     YFTADIAPLQQIKVVQPGEQIKAIDSRTGWWMIAENDRLGWISAGPTSYWDNNTSTFPL
                     LLKANSKLAVNEVGIIYNYSKGEKITVVEGSVAGWWKVKTPNGYYGWINAKPTHYDSNK
                     NLIASENLPVYFSGKEPSNSNEQLSKQQLVLREAYKHLGKPYVTAGKGPDAFDCSGFTS
                     YVYRHALGIEIGGWTGAQINSGREVSRADLQPGDLVFPHSDHVGIYVGNGQMIHAP"
     gene            30457..31626
                     /locus_tag="CLOSPO_RS19265"
                     /old_locus_tag="CLOSPO_02883"
     CDS             30457..31626
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:PF00009.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001387889.1"
                     /locus_tag="CLOSPO_RS19265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02883"
                     /product="GTP-binding protein"
                     /protein_id="WP_003485442.1"
                     /transl_table=11
                     /translation="MHKTIGILAHVDAGKTTFAEQILYHTKSIKIRGRVDHKNSFLDNH
                     KIEKERGITVFSEQGTFNYKDSTYYLIDTPGHMDFSSEMERAIQVMDYAVIIISGVEGI
                     QGHTETVWNLLRKHNIPVLFFINKIDRVGANAENVIEDIKLNFTKKVCFIDKPLNSDEL
                     SPELIEFIAEQDEYLLEKYLEDNYEKDLWLKSMKKLIKKSELFPCFIGSALQDIGIEDF
                     LENLHVLTYTEYNEEEKFSGRVYKIRHDEENNRLTYIKALSGSLKVKEEIALPNIENDF
                     CEKVNEIRIYNGDKYINVDKAEAGQIFAVTGLSSANIGDGIGTLKDKATYNMVPTLKSK
                     VIFDESLNVKDVLKYFKILESEDPSLNIIWDEKFQEIQVYIMGVIQLEV"
     gene            31636..32412
                     /locus_tag="CLOSPO_RS19270"
                     /old_locus_tag="CLOSPO_02884"
     CDS             31636..32412
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:PF03764.16"
                     /locus_tag="CLOSPO_RS19270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_02884"
                     /product="hypothetical protein"
                     /protein_id="WP_003485444.1"
                     /transl_table=11
                     /translation="MEERFGISIDFGPCEILYKETILDTVIGYGHFEPLKHYCEVHLKL
                     EAAERNSGITFESVCHTDDLTTGNQNLVKTHIFERDHHGILTGSPITDIKITLLTGRAH
                     NKHTSGGDFREATFRALRQGLEKAKNVLLEPYYSFKMEVPLDYMGRVLSDIQKLKGDFN
                     PPETIHNKAIIKGRGPVATFMNYSVEFISFTKGKGKFNFVFDVYDICHNEKEVIEKIDY
                     DKNADIEYTSTSIFCSKGQSFLVKYDEVEEYMHCLK"
     gene            32465..>32611
                     /locus_tag="CLOSPO_RS19275"
                     /pseudo=""
     CDS             32465..>32611
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001254594.1"
                     /locus_tag="CLOSPO_RS19275"
                     /note="incomplete; partial in the middle of a contig;
                     missing stop; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNNILENSISDVLVKQIDSIMVPRSNKVDSRTFSRLLDDDKVVAS
                     YKMY"
ORIGIN
        1 aatttaccta tattatataa tgaagagaga catattatag gtatatgcta taaagaaaaa
       61 ggtaatgagg aagctacaaa gcttggattt aagcttgtat ctggaagtgt aaaagaagaa
      121 agagtgaatt catgggtaaa atattttagg gaaaatccta atactataat tcattgcttt
      181 agagggggag accgttcaac tatagcacag gagtggatat atgaagcaac aggtcaatat
      241 atagtaaagc tagaaggggg atataaggca tttcgtaatc atcttataaa ctcattagag
      301 cctgaaaata ttaaatcgaa gcctttagtt ttaactggat atacaggttc aggtaaaaca
      361 atattattaa ataaactaaa gaattctata gatctagagg gaattgcaca tcatagaggc
      421 tccacctttg gtcattttat tacaccacaa aaaacacaaa taaactttga aaatagctta
      481 gcctatagtg taatcaaaca tgaggataaa aattataaat atatgatttt agaagatgaa
      541 agtaaaaaca ttgggaagaa tttcatacca aaaggttttt ataatcattt tcacagtgga
      601 gatgtaatat tcttagatgc tactgtagaa gaaagagtgg aaaatatatt acaagaatat
      661 gtggtaaatg gtcaaaagga gcatattgaa gcactaaaat atagagattt agcattagaa
      721 tcttggttaa atgatatggt ttctagtata gaaagagtta aaggtaagct tggcggagac
      781 aggatgaagg taataataga agagcttaaa ctagcttaca aaactcaaat agaaactaat
      841 agcattgata ggcacagaaa ttggatagaa ttatttttaa ctaattatta tgatcctatg
      901 tataagcatt ccatagataa atctaatagg aatgtaatat ttaaaggtaa tagtatagaa
      961 gtattagagt atatagaaga attagaaaaa taatggataa acagagtttt aagctttaga
     1021 gggagttttt acgccctcta aagcttaaaa atcgttatct aggggcgtat ccgctcttta
     1081 ctccaacttt gaagaaaagc agagagtcca aatcttcgat ttggtgcgaa tcgctttcac
     1141 agagtgcgat gagagtatta gagcgggtag tcatcagata aaagtagaag tgaatcttta
     1201 atgaaaaaat ttacaggcta aataggaaaa actataaaat cttatataaa gattaaatta
     1261 gaagaacaga agacaatgcc ttgggaaagt aaattaggag gatatcctgc ttttactcaa
     1321 tgtgatccac gatattatga taagaatcta gaaagattta atacattatt gcttcaatta
     1381 gattgtgaag atgaatgtga tgtaatgttt ggagatgctg gagtagccaa cttttttata
     1441 aatgaagaag atttaaagaa acttgatttt actaaagttt tatataattg ggattgctgc
     1501 taagtataaa ttttgatata tatgtaagaa tacatgtaac tttgttcctc acacaaccat
     1561 attataaaat gtaaagatta ttaaagtggt gagggtgaga aggatgtatt tatacccaat
     1621 gacaaatttt tatggtagtg aaccatatcg cacagatgaa ttgttagaac cagtatatgg
     1681 tcctaatatt tatccagtta ccgaagcaga ttcaggagta gaccctaatt atatatatcc
     1741 cgaatacaga tctatagatg atatggatta tcatgatatg tttagagtta ctgaatcaga
     1801 aatgtcccta agagatacca tgcgtatgct ttgggaacaa cattctgttt ggacaagatt
     1861 ggctataatg agtatagtag caggttcacc gaatgaggac cttgttgtag ctaggcttct
     1921 tagaaatcct aaagattttg aggaagcatt aagacctttc tatggtgatg aggttgctgc
     1981 tgaatttaat aagttactta caagtcatct tgttatagct tcagaaattg ttaaagcctc
     2041 taaggcaggg aatactgatg cagcagcaga tgctgaaaaa agatggtacg aaaatgcaga
     2101 caaaattgct gagctactta gcaaaattaa tccttattgg tactttgaag attggcaagc
     2161 aatgttacat gaacatttag cacttgttaa agctgaagca gttgctatac ttacatcaga
     2221 ttatgaaaaa ggtatttcca tatatgatga tattgaaatg caggctttag aaatggcaga
     2281 tatgatggca gatggcattg taaaacagtt tccagaaaga tttcaagatt aaactttaaa
     2341 aacaattaat tttttattaa aaggatatgt tagattaaaa tattgattta taacacaaaa
     2401 taaggtagtc agtgttgact accttattaa aactttattt atctttaatt aaatttacat
     2461 ggatttttcc ttttgttaag caataacaca tatatatacc ccaagtcatt ataaatacaa
     2521 aagaaatccc ttcacagaag ccaaatgtaa aattagataa tgatttgctt tacctatttt
     2581 gtttggtgtt ttatcttatt tataaaatcc tgcttcgtta ttacaacagg ggtaactggc
     2641 tcaccataaa aatctattgg gtttcctaat acttcacatc caagctgttt taatattatt
     2701 acagttacat ctcttgcatc tataaaaact ttttccacat taagattaaa catttcattt
     2761 agagaaaata tagccatttt tttgcctatt cctaagccac ggagcctttt atcaactgca
     2821 aatcttcccc aatgccattg attattttcc tgccaacagg ctaccactcc aataatgtct
     2881 tcacctactc ttgcacacca ccaaatttgc ttcaaatctt tatttatagg tattaattct
     2941 ttaggaatat tttgttcata agcaaatatt tctgtggtta accttattgc atcatccaga
     3001 taatttgatg ataatctttc tatttttatt cgagaaccat cctttataag attatttttt
     3061 aatgcaagaa tacgaaattc ttttaaggat tttgaaatgt tatcattaac agtgtcattt
     3121 cctagatcta ggatttcatt gataaactta ttagcctcca tatctccatt tatcatagat
     3181 tccaatcctg atgaaagaag gctaatgtgt tttattcttt tgtcattagg agacttttct
     3241 attttaataa aatttttagc ttttaaacta ttaagaattc tacttaagga agctttatca
     3301 attcctaatt gtattgtcaa ttcgttaaaa ggagtaatgc cattctgttt aagatagttc
     3361 aatacatgag cttgtactaa tgtaagtcca gaatttagac aattataatt aagtagtccc
     3421 aattctctta tgattagtct tagttctttt ctaactattt ctgccttatt caatttaaca
     3481 tctccattcg ttgatattat caatgaaaat attatactat attcagattt gcactgcaat
     3541 gtataaaagg gcaaatatga taaaattatc tttactattt ttgaggtttt ttagtttacg
     3601 cacagaaaat tcaaatgaag ctgctcaact gtctggaatg gcacagtcat tgggatatct
     3661 gcttgccgcc tttgatccaa tattattcgg atttctccac gatgcaacta atagctagaa
     3721 ggttccactt caagcactaa tcggattaca gtcttattat ttatatttgg tctaggtgca
     3781 tctcgtaata ggtatatagg ctcatcctta taagtggtaa ggtagatgaa atttatgtaa
     3841 aacaaaaaca aagctcccca tcagtataac tatgataatg atggggaatt ttgataattt
     3901 tggattatgt tgattttaag cttatgtgtt tgctcataat ctttttaagg attttttagc
     3961 aagaaataca gctataatta gtgttattat ttctgacaaa ggaaaactaa gccatatccc
     4021 agtcatttga aagaaataag atagaaataa agctacagga acaataatgc aaccactacg
     4081 taaaattgaa atggtgaaag catgtcttgg ttcatttata gaacttaata cagctgatgt
     4141 aataatatta attcctgcaa agaagaaacc agcaaaataa ataatcaatc cattagatgc
     4201 agtttttgag agaattttta tatgatctct attgaatatt tctactaatt gattattgaa
     4261 aataacaacg agaaaatata aaacaattga aactacaagg gatgcataga ttgcatattt
     4321 aaataattgt agaatttttt tattatttcc ttgcccaaaa ttttcactca ataaaggttg
     4381 tgttccttga gcaatgcctg taaaaataga agttgctacc aaagccaaat tagccacaat
     4441 accataggct gccacaccta tatttccgga aatatttaat ataagtaaat taaatacaat
     4501 aagaataaca ccagaagcaa tttctgtaat gaaggatgat attcctaaac tacaaatata
     4561 agttatctgc tttattgata attttgactt atgaaaatgg aagtgatttt tctttttaat
     4621 atagtgcctt gttaaaatac acatactaat aataggtgct agccctgttg caaaagctgc
     4681 tccaaacatt ccccactgaa gaggaaaaat aaaaacatag tctaaaataa tgtttgataa
     4741 acttccaatt aacattcctg ccattgacag cttaggattt ccgtcatttc taataaaagc
     4801 tataaaaata ttattaagaa taaaaaaagg tgcaaaacat agtagtgttt ttagataggt
     4861 atttgtcatg cgaaagatat tttcatctgc tcctaataaa ctactaagtg ttgatgatcc
     4921 aaataaacca atcagtaaaa aaaatattcc caagagaatc ccaattttaa tagagtttgt
     4981 aaaaacaata tttgctttgt tatgcttatt tcgtgcttga taaatagaat attttgtagc
     5041 accaccaatt ccaattaaaa gtcctgttgc attaataaaa ctgtaaatgg aaattgataa
     5101 atttagagct gttaatccct gtactcctaa tcccttagat ataaaaaaag tatctgctaa
     5161 aatatagcat gaaagaccaa tcattcctat aatatttgtt aagatatagc gtataaatgt
     5221 atttttaata ctcattttta tgattcctcc taaaaataaa cataaaaaaa tacctaacat
     5281 ttattcctac taagacctaa aggaataaag ttaagtacta tgaaatgagt tacccggtgg
     5341 aaacccatta gtatttaata ttaaattttc taaataatat catatttcat tagattttgt
     5401 caagaaggta taaatttaaa agctgatgtg aataaaagaa taaagaaaga taagtataac
     5461 cctatacagc aaacaagtat tgcatttaca ggtgactata taactaagag aagaaaatgc
     5521 aaaaagaaac tttggtgagc ttatttattt tagagggaaa tcacaatttt tcactataat
     5581 ttgacacaaa tccccttgta atagtgttgt attcttaata taatattggt ataatacatt
     5641 aagaaaagtt tattataaac ttagtttgat tgttataatt gtaggttaat tttatattta
     5701 agttaaagaa taccaaattc attcatatct tgatattttt ttataggaga aaatgcatat
     5761 gaaagaattt agtattaata cagatgtcta ttttggagaa ggatctttag atagactaaa
     5821 ggaaattaaa aataaaagag tactaattgt atgtgataaa tttatggaaa cttcaggtat
     5881 ggctgcaaaa gtacaacaaa aacttgttga ttgtgaagta gctatatata gcgatattgt
     5941 acctgatcca tctgtagaag ttattgcatc tggtattcaa aaacttcaaa gttgcaatgc
     6001 agagattatg atagctcttg gtggaggttc atcaattgat ggagctaagg ccatgagaga
     6061 atatgcgaaa aaaattactg gaggagtttc cactatagaa gagttttatg ctatacctac
     6121 tacaagtggt acaggctctg aagtaactga atatgcagta attacaaata aacaagaagg
     6181 attaaagtat gctcttacag ataaatcact tcttcctacg gttgctattc ttgaccctga
     6241 gttggttaaa tctgtaccca aagctataac tgcggataca ggaatggatg taatcacaca
     6301 tgccatggag gcctatgttt caaaaaatgc tactgatttt tcagatgctc ttgcagaaaa
     6361 agcctttact ttagctttta gatttttacc acaggcttat gctgatggga atgatattat
     6421 agcaagagaa aaacttcaca atgcatcatg ccttgctggt atggctttta atgcagcagg
     6481 acttggaatt actcatagtt tagctcatgc agtaggtggg aagttacata tttctcatgg
     6541 aagaagtaat gcaataatac ttccttacgt agttgaatat aatgctagtt taaataaaga
     6601 aacctttaat gttgaatatg acgtagcagc taagaaatat caaaggcttg ctaagttatt
     6661 gaagttgcat gcgccaaatg taaatattgg tgttaataat ctaattaaaa gtattgtaga
     6721 acttcaaaat acattaatga ttccagccac attaaaagaa caaggggctg atatggcttt
     6781 ggctgaagcg tcaagagaag agattattaa tgcagctctt aaggatgtgt gtacaacagc
     6841 aaatcctaga gaagctacaa aggaagattt atcaaaaatt ttagaaaaag ttttaggata
     6901 gactatttta taccactcag taatgggtgg tattttgctc aaattttcag aaaaattgaa
     6961 aaattaaata gaatttataa tataaaaaaa taagggggat taatatggaa gatgaattat
     7021 attcaatagg taaagttggt aagatatgca aaataacaaa aaaagcatta agatattatg
     7081 acaaaatgga catattatca cctgataaag tagctgatga aagtggttac agatattata
     7141 gcaagaatac tttattatct gttccagtta taaaatatta taaacaaagt ggatttaagc
     7201 ttgaagaaat gaaaggtttt ttagagggta agacctatga tttttttcat acaagtttta
     7261 gaaataaaat agatgaatta aaagaacttg aaaaagaaat aaatttaaaa ttaagatccg
     7321 ttaaggattg ggatgatctt atagttgaag cccaaatggt aattgaaaat aatgtttctg
     7381 atgtagctat aaaatatata gataatcgta ctttaacttt tttagatcaa gattttgaat
     7441 atgactatat ggattctata attaacatag aatttacaaa ttacatagat agtatagata
     7501 atgcaataac agggcctgta atcatacgtt ttccatgctt tcaagataag atgaatggaa
     7561 aatgcaataa gatgaggata atgcaggaga caattttaaa atgtaaggaa gaattgagtg
     7621 tggaatttgg tggctggatg gtagccgctt gttatcatat aggacctcat gagaccatta
     7681 gtgaaacata taaaaaaata aaggattgga ctgaaaaaca tggttatata tgttctgaag
     7741 aatcctatga aagatatgta acagattatt ggacaactaa aaatagaaat agatttgtaa
     7801 cagaagtttt aataaaaatc agtagagaaa aataatttag ccccggtgaa aacgttgacc
     7861 ctagggtaga ctataaaggg ttaactatac tcctttcgtt aaaaaaaaca caatattatt
     7921 aaacaaaaca caagcttatt gtttttatat aattaaaaat acctggatta ttatccaggt
     7981 atttctatat ttatcaatta agaatatcaa atgtaacttt aacttaatga agggtttaga
     8041 ggtatttatt gagttctcat tggtagatat aatactaatt tttttaatct tatttaaata
     8101 ttcttgaaaa atacatattg accctaccct atagggcagg gaatataatc tacttaagaa
     8161 taaagtacct acaagataga aagtgaaaag gtgttcagta attttaatgt agaatgcacc
     8221 aaattataac aatcttaatg tatatttatt ataaattttt atttaacaat ataaatttgt
     8281 aatattatta attttttata agcgaaagga gaattatttt atgaatggag attcaaaagc
     8341 agtaagctta gaagcagttg ctgcaaagaa gaaattatca agtgatttct tcaaaaaggg
     8401 tatatccctg gctttatttt caggacttgc ctatggatta tatacagcgt ttttaactat
     8461 gggtatgact aaaggcgttt ggggggactg gtatggtcct aatacagcag gtttatcagc
     8521 atttgctata gcatacttgc ttgcagctct cggtaacgca ataaacgata catgcagtgc
     8581 tgtttgggca cttttgtatg caggagttaa aggtaaattt ggagactttt taagatgcat
     8641 caacacaaaa ccaggacgca tcatgatatt agcagctctt atcggaggac ctatagctgg
     8701 tactgcttat gttatagctc ttcaaatggc tggttcaata gttgttccaa tatcagctct
     8761 ttgccctgca attgcagcta tactaggtaa aattttgtac aaacaagaac taaataagcg
     8821 tatggctttt ggtattttaa tatgcgtatg tgcaagtttt ctaattggta gtacaggcct
     8881 tagtggcggt gcttcagcaa atacattaat tggtattgca atagctatta ttgcagcttt
     8941 aggttgggga tttgaaggtt gtgtagctgg atatggtaca gcaatgattg accctgaaat
     9001 tggtatttgt attcgtcaag taacatcagg tatagcaaac ttattcatct tagttccaat
     9061 tttcggaatg atggctggtg gaattggaat ctctactgac cttgccgtaa aagcatttac
     9121 aagttctcct gcaatggttt ggtttgcttt aagtggactt ttatcatttg taacattcat
     9181 gacatggtat gctggaaaca gtatgtgtgg agcaggactt ggtactgcat gcaatggtac
     9241 atattctttc tttggaccat tattctgctt attagtatta ggagtatatg gtggaatgga
     9301 cggatggtca ttacctcctg tagcttggat tggagctgta ataatgatgt ttggtattct
     9361 tacaatatct atgaatccac ttgatttatt caaaggaaag aaaatggagg tagatataga
     9421 tgaaaccgct taattatgca attttaaaat attttactaa agtttcagaa gcttgtgctg
     9481 atgatgttat aaaggcatta aaaggacaat atggaagttt taaggctcta aacaaaaaag
     9541 ctgtaattaa tgcactactt acagcagaag ctaatggtct tattgaagaa acaagattcg
     9601 atttagataa taacaatgag ttaagagttt actaccatgc acatgcagaa ggtgcggaaa
     9661 caatcaacaa gtatattccg gattaatttc taacattaac cataggggaa tccttgtgaa
     9721 aaataaatct tatgaaattt tataataata gctttaaata tttaatttta gtaagcataa
     9781 taattaaatt tcaacttaaa atataagatt tgctataagt tttttcaata tttttatttt
     9841 aaaaaatata ttgactttcc cccaaagggt aagggatata atcaggatat agcaataaaa
     9901 aatgtatgaa aacctacaca gaatatatag aagagttaat aatagaagtt atagttaata
     9961 aaaagtatat tgggctaaaa ttaggaagga ggaattaaaa atgagatatt atggagatga
    10021 ggctttaggc cttgtggaaa caataggatt agttcctgca cttgaagctg cagacaaaat
    10081 gcttaaagca gctaatgttg aattaatttc ttatgaaaat attggttcaa cccttgtaac
    10141 aattatggta aaaggggatg ttggtgcagt aaaatctgct gtagaagcag gtgctgaagc
    10201 agctagagct atcggtaaat taacagcaca caatgttatg ccacgtccta ttagagaagt
    10261 tggagatatt gtttcagtac acgatatcga ttcataaaat agaaaggaaa tgatatacat
    10321 atggcaagat atgaagcttt aggattaatc gaaacttttg gtctggtttt tgctttagaa
    10381 gcagcagacg ctatgtgcaa atcagcagat gttgaactta taggatatga aaatgttgca
    10441 tcaggttata tatctgtatt agttcgtggt gatgttgggg cttgtaaaac agcagtagat
    10501 gctggtgttg cagcagtcaa tggaatggaa ggtggaagcc tatatagctc aatagttatt
    10561 ccaagaccac acgaagatct tgaaaaaata ataaaacgtt atgccattcc agatcttata
    10621 acagaataga aaaatgaatt ttttctaaag aaaaggagag agaaagatga atattataga
    10681 taatgattta ctctccatgc aggaagctag aattcttgtt gaaaatgccc gagaggcaca
    10741 aaaaaaatta gctactttcc cacaagaaaa acttgatgag atagttgagc gtatggctga
    10801 agaagttgaa aaacatttaa aagagcttgc aaaaatatct aatgaagaaa cagagtatgg
    10861 aaagtggcaa gataaatatg ttaaaaatca ctttgtatgt gagtatttaa aaaacaaact
    10921 caaaggtatg aggtgtgtag gtattattaa tgaagataaa attaataaaa ccatggatgt
    10981 tggtgtacca atgggggttg ttatagcctt cccaccagca acaagtccag tatctactac
    11041 tatatataaa gcattaattg caataaagtc aggaaatgca attatatttt cacctcataa
    11101 aagagctaaa aatacaattt ctaaaacagt ggatatttta attaaagctg cagaaggtgt
    11161 aggacttcca gaaggtgctc ttgcatatct tcacacagta actgaaagtg gttcattaga
    11221 gcttatgaag cataaagata catctttaat aatgaacact ggagttatag aaatgcttga
    11281 tgaagcctat agatctggta agccagtaat atatggaggc aatggaaacg gacctgcctt
    11341 tatagaacgt acagctgata tagaaaaagc ggttaaagat attattacaa gcaagaattt
    11401 tgattatgga gttgtgtctg ccgcagaaca atcaattgtt gtagatagct taattgcatc
    11461 tgaagtaaag caagaactta ttaaaaatgg tggatatttt atgacagaag aagaagcttt
    11521 aaaactagga aagattttgt ttaatcaaaa tggaacccca gatttagaga tgattggtaa
    11581 gtctccacag tttttagcta agaaagctgg ctttcaagtt tcagaaggta taaaagtgct
    11641 tatttccaat gagaagtttg tttctaagaa taatccttat tcaagagaaa aactttgccc
    11701 ggttttagcc ttttatatag aggatgactg gatgcatgct tgtgaaaaat gtatagaatt
    11761 attacttact gaaagatatg gacatacact tgtgatacat tcaaaggatg aagaagttat
    11821 tcgtcaattt gcacttaaaa aacctgttgg tagagtgctt gtaaacactg caggaacctt
    11881 tggcagtatg ggggctacta ctaatttgtt cccttcaatg acattaggaa gtggatctgc
    11941 aggacaagga atgacttcag ataatgtttc acctatgaat ctactttata tacgtaaagt
    12001 tggatatgga gttcgcatgg tggatgaaat tgttaaaaca gtaaatgata aagaggattc
    12061 tatttctgca atttcaaatg gaaatgaaat agataactat aagttattag agagtatttt
    12121 aaaaaaagtt ctacaggact taaaataaaa aatcatattt aatatatgaa atacattaaa
    12181 gaatgtgagg gaataaattg gatatacgtg aattttcaaa taaatttatg gaagctacta
    12241 aaaatatgtc tgatgaagaa cgcgctggct taatgaagat gtttcaaagt gtttctaatg
    12301 aaataacaaa agaagaacca gctacatcaa aggttgcgtg tgacaataat ggtgaaatac
    12361 cagatggaat gacagaacgt ctagttaagt taaaagaaaa ttatatgaaa catgttccat
    12421 caataacaac tcatagagca agagctatta ctaaaatagc taaagaaaac cctggtattc
    12481 ctaaatcagt tttacgtggt aaatgtttta aacattgttg cgaaactgca ccacttttaa
    12541 ttcaagacca cgaacttatc gttggagcac caaacggaaa acctcgtgca ggagcatttt
    12601 ctcctgatat agcttggaga tggatggttg atgaaattga tacaatagga actcgtccac
    12661 aagatccatt ctatatatca gaagaagata agaaaattat gcgtgaggaa ctattcccat
    12721 attgggcagg taaatccgtt gatgaatact gcgaagatca atatcgtgaa gcaggagtat
    12781 gggaactttc aggagaatct tttgtttcag attgttcata ccacgcagta aatggtggag
    12841 gagactctaa cccaggatat gacgttgtat taatgaaaaa aggtatgctt gacataaaga
    12901 gagaagcaga agaaaaatta gctgaactta aatatgaaaa tccagaggat atagataaaa
    12961 tctatttcta taaatcatta attgatactg ctgaaggtgt tatgatatat gctaaacgta
    13021 tgtcagatta tgctgctgaa ttagctcaaa aagaaactaa ccctaagcgt aaagcagaac
    13081 ttcaaaagat ttctgaaata aatgctagag ttccagcaca taagccaagt acttactggg
    13141 aagcaattca agcagtttgg actatagaat cattacttgt agttgaggaa aaccaaacag
    13201 gtatgtctat aggacgtgtt gaccaataca tgtatccatt ctacaaagct gatattgaag
    13261 ctggacgtat gactgattat gaagcatttg aattatcagg ttgtatgctt ataaaaatgt
    13321 ctgaaatgat gtggataaca agtgaaggtg gttctaaatt cttcgcaggt tatcaaccat
    13381 ttgtaaatat gtgtttaggt ggtgttacta gagaaggtcg tgatgcaaca aacgaattaa
    13441 catacctttt aatggatgca gttcgtcatg ttaaaatata tcaaccatct ttagcttgcc
    13501 gtatacacaa aggatcacca caaaaatatc ttaaaaagat agttgacgtt attcgtgcag
    13561 gtatgggatt cccagcatgc cactttgacg atgttcatat aaaaattatg ttagctaaag
    13621 gtgtttctat agaagatgca agagattact gcttaatggg atgcgttgaa ccacaaaaat
    13681 ccggaagact ttatcaatgg acttctacag gatacactca atggcctata tgtatagaac
    13741 ttgttttaaa ccatggtgta ccattatggt atggtaaaca agtatgccca gatatgggag
    13801 atttaagcca gtttaaaact tacgaacaat ttgaagcagc tgttaaagag caaattaaat
    13861 tcattactaa atggacaagt gttgctacag taatttctca acgtgttcat aaggaacttg
    13921 caccaaaacc acttatgtct atgatgtatg aaggttgtat ggaaaatggt aaaggagtag
    13981 aagctggcgg agctatgtat aacttcggac caggagtagt atggagtgga cttgctactt
    14041 atacagattc catggcagct ataaagaaat tagtatttga agataagaaa tacacactac
    14101 aagaaatgaa cgaagcttta aaagcagatt tcgttggata tgaacaatta aaaaaagatt
    14161 gtttagaagc acctaagtat ggtaacgatg atgattatgc agatttaatt gctgctgatt
    14221 taattaactt tacagaacaa gaacatcgta aatataagac attatattca gtacttagtc
    14281 atggtacttt atcaatatca aacaatactc catttggaca aatgactgga gctacagcaa
    14341 atggacgtag agcatggatg cctttatcag atggtataag tccatcacaa ggcgctgatt
    14401 ttaaaggccc tacttctata ataaaatctg tttctaagat gtcttgtgaa gatatgaata
    14461 taggtatggt tcacaacttt aagttaatat ctggtcttct tgatacacca gaaggagaac
    14521 aaggaatcat tacattatta cgtagtgcgt gtgcccttca acttggagaa gttcaattta
    14581 actatttaga caacaagact ttaatagaag ctcaaaaaca tccagatcaa tatcgtgatt
    14641 taattgttcg tgttgctgga tacagtgcat tcttcgttga gttatgtaaa gatgttcaag
    14701 atgaaattat aagtagaact atgcttacac atttctaata aaaatttgat ggaaaatata
    14761 taacttatag aaaatatata acttatagaa aatatataac ttagtccctt taaaataatt
    14821 tatataaagt ctgcaatcta cagcctgttt tgtagattgc agatgtaaat taagatatat
    14881 attaaaaatc aaagtaaatg aaactggaga atgagtaata tgagtaatgg aaatttaggt
    14941 ataatcgaga gaaaagcaag gatttttaat atacaaaaat ataatatgta tgatggagat
    15001 ggaataagaa ctttagtatt ttttcaagga tgtccactta gatgtaaatg gtgtgcaaat
    15061 cctgaaggac tagaaaaaaa atatagagtt atgcttaaaa gtaatctatg tgtaaattgt
    15121 ggagcttgtg tttctgcatg tcctgtagga attcatacta tttctaataa aactctaaag
    15181 catgaagtta atcgtgacat agattgtata ggatgtggaa agtgtaaaga agcttgtctt
    15241 aaatctgcta tatcaatagt tggagaagaa aaaactatct ctgaactttt aaaaatagta
    15301 gaagaagata gaacctttta tgaaatgtcc ggcggtggag ttacattagg tggtggcgaa
    15361 gttttaatgc agcctgaagc tgctactagt ttattaatgg catgtaagca agaaggtata
    15421 aacactgcaa ttgaaacctg tggttataca aaacttgaaa caatacttaa ggttgcagaa
    15481 tttgtagact tattcttatt tgatattaaa aatattaatt ctgatagaca ttatgaatta
    15541 actggagtaa gaaatgagag gattttagag aatcttcaag aattactcaa gaaaaaatac
    15601 aatgtaaaga ttcgtatgcc tttacttaaa ggtataaatg attctcaaga tgagatagaa
    15661 aaaactatgg aatttttatt accttataaa gattataaaa actttaaagg aattgattta
    15721 cttccttatc ataagatggg ggtaaataaa tataaccaat taggaatgga atatcctata
    15781 aaagatgatc caagccttaa aaatgaggat ttagatagaa tagaatcttg gatcaaaaag
    15841 tacgatttac ctgtaaaggt gatccgccat taaataattt tcaaatagat aataagatgg
    15901 aaggtaaggt ttatgggaga tttttctgat agaaatatac agcgtgttat acaagaatca
    15961 gtgccaggaa aacagattac tatagctcat gttattgcat caccaatgcc tgatatatat
    16021 gatcgtcttg gaattgatga aaaaggagca ataggtattt tgactttatc accctttgaa
    16081 acagctatta ttgcagcaga tattgctaca aaggcttctg atgttgaaat tggatttctt
    16141 gatcgtttta caggctctgt tgtaataagt ggtgatattc aaagtgttga aacagctctt
    16201 agtgcagtta atgatacgct aaaggatatg cttggattta ccaccgctcc cattacaaga
    16261 acatgagaaa aaagcgcata atggtaattg gcccttcaaa atgtggcaaa actacattag
    16321 ttaatgcatt aaacgattat gatggtccat taaggcgaac accagattta atttatggta
    16381 agaataccat tgatgttcca ggttcctata tagagaatgc atggatgtac aaacatataa
    16441 ttgcagcagc tcaggatgca tcttgtgtgc ttatattggt tgaccaatct aattgcactg
    16501 aaatatactc ccatggattt gcaaagtctt ttagatgtcc agtaattggg gttatagcaa
    16561 aatgtgattt gatgcctaag aataaagaaa aatgtgaaat gcagttaaaa aagatagggg
    16621 tatcagagcc atattttcat attagctttg aaatgggaac aggaattgat gctttaaaaa
    16681 agtatttatt tgaaaaaggt gaggagtaaa ggtcgatgat gaaatttatt acggaagagt
    16741 atttaagaga tttatataga aaagaacctt ttaataccta caagttagaa caaggacagc
    16801 gccttacccc tggagcagct gagtatttat ctgataaagg aataaaattg agtgatgatt
    16861 taaaagtaaa taagtcttca aaaataaatg cgaatatttc cccaaaaaac tcagcaaaaa
    16921 caccggaaga aacatctaag gaaataatga aagatgtggg aaatagtgat gtgaatttca
    16981 atttgaataa gaagctttgc ttaagattga aatccatgga ggctaaattt cttgttgtta
    17041 gtagtgaaat attaaaagaa gatattattt tagcacagaa tattataaat ttaggtagga
    17101 aaatatcaaa catcagaaat gttttagatg gaaaaggtac tcttgaacct atttatttaa
    17161 aagaatgtac cgggatgaat tcatcaaatt ctgaagcgga tcttgatgat tgttttgaaa
    17221 taacagaatt tcatatgcaa tttccaaaaa gcaatgcaat tttaaaaatg aacgtacttc
    17281 gttgtgcggt gcaggaatta cagcttgaaa taattgatac atataaaagt gatgatgaaa
    17341 gtttaaaaag caaaattatg gacaatgtta atttaataat taattcactg tcccaattaa
    17401 tttgtttagc agtaggagga aaagaatgtc agaggaaaaa ttaacttttg aatattgtga
    17461 taatatggtt cgaaagtttg aagaagttat agaaaagcca attgttaatg ggtcttctgt
    17521 ttattacaca ggtgtggacc taggtactgc ctgtgtggta ttagctgttt tagatgaaaa
    17581 ctacaaccca gtggcgggtg catatagata tgctgatgta gttcgtgatg gtatggttgt
    17641 tgactatatt ggagcagtaa ggattgtgag agaacttaaa gaagaaattg aagaaaaatt
    17701 aaatacagaa cttatttatg ctgctgctgc aattccacct ggaacggatg ccttagattc
    17761 tggagcaatt aaaaatgtag ttcaatcagc aggatttgaa ttgacatgtc ttttagatga
    17821 acctactgct gctaatgctg tacttaaaat tcaaaatggt gcggttgtag atatcggcgg
    17881 tggaacaact ggaatatcaa ttttaaaaga tggaaaagtt gtttatgttg ttgatgaacc
    17941 tacaggtggt actcattttt cattagttat ttcaggtgca tatgaaatgc cttttaataa
    18001 agcagatgaa tacaaaagag ataataaaaa tcacaaggaa attttaccag tactaaaacc
    18061 agtggttgaa aaggtgtcat caattattaa taatcatatt aaaaattatg atgttaatga
    18121 aatttcttta gtaggcggta cttgttgttt aacaggaatt gaagaaatta ttgaaaagca
    18181 aacaggagta tatactcaca agcctagaaa tcctatgttc gttacaccac ttggaatagc
    18241 attaagctgt acacgagata ttatagaata agacacatga aaataaatat actgccatgt
    18301 ttgacttgtt atttattttc atgtgcctaa taaggagagt gtttaaaagt ggattttaga
    18361 attataaaat caccttctag tagcactaaa gatattctta gaagacgaat gggtggaaac
    18421 tgcaaagcgg atttagaaag tgctgatgca ataggacttg ttcaaggtaa acttatcgat
    18481 atgatttatg ctgcagatat tgctgagaaa gctgttggag ttaccgttga agatattaga
    18541 ggcacatgtc ctcagcacat ggttttactt ggtatttttg gtgacacatc atcagttgaa
    18601 gccgcattaa atgagattaa attaaaaatg aaagaggtaa aataagtatg atagcagcaa
    18661 gacttattga taatgtatgg gccactagaa aagcagaatc ccttagcgga cttaaattta
    18721 tgcttgctga ggaaattggt gggatagatg aaggacgcag atttattgtt gttgatatta
    18781 tcagtgcagg tatcggtgat agagttattg ttagtactgg atcatctgct cgcagaatgt
    18841 taggtgatga taatattcct gtagatgcag ttgttattgg aataattgat gaggattgca
    18901 attttggtta gaacacaact ttcttaaaat aaacataata tttaaaacac atgcaaaatc
    18961 ttaaataggc atgcaaaatc taagattttg aagtgatcac ttacacagaa tattggtttt
    19021 ggtatgctag cttactcatt ctattatatg agaaggagtt ttatatagag attttgatat
    19081 tatttgaaag tttgaaagga tgtgagaaca tgaaaaaatt aatcgctgca aaagacattg
    19141 aagccctaat attaaagggt gaaaaagtac tttatgtaga tggtactgaa ataataacac
    19201 catcagctaa ggatcttgta aaaaataatg gaatagtaat tactacagaa gctcctgcac
    19261 ctaaagtaga gcatttaata ggtaaaaatg ttccaaacat agagggcatt gatagtgaaa
    19321 tgatgcttaa attccttaga gcaatgatgg acaagggtct tctacaagag atgcttcaat
    19381 gtttaaaagg gaaggatctt ccatttaaag ctgagtgtga tcctaatgga cttaaagttg
    19441 ttagaggaaa ttcagtgaaa atggatgtat ttgatactgg taatccaaat gcaaaggttc
    19501 aatttcaaga attagtaagt aaagaagaat caaaaatgag tgcaggattt ttaattatcg
    19561 aaaactcaaa atttgattgg gaattaactt acgaagagat tgattatgtt attgagggaa
    19621 ctttaaccgt tgaaattaat ggaaagacat atacagctta tcctggagat gtattgtttg
    19681 taccatcagg ttctaaagtg gtttggggat ccccagataa agctagggta ttttatacaa
    19741 catatccagc aaattgggcg gatcttttat agaagattag gaggatttac ctatgcaagc
    19801 gcttggttta atagaaacaa agggattact tgcagctgtt gaagcagctg atacaatggt
    19861 gaaatcagca gatgtaagta ttatcgaaaa aacttatgta ggtggcggcc ttgttacaat
    19921 ttcagttaca ggggatgtag gtgcagtaaa agcatctata gaagctggag tagcagctgt
    19981 aaaaaaactt gatgaaggat ttttagtttc agaacatgta attccacgtc cccatgagga
    20041 actggaaagc ataataggac ctaatactcc accagaagat ccatcatcta atgataatac
    20101 agaaaatgtg gaagatgcag atgatacaga ggctgtagaa aaagcagagg atacagaaaa
    20161 ggtagaaaat acaaaagctg tagatagtgt ggaagataca gaatccgtag aagttacaaa
    20221 agatatagta gatgtaaaga atgtagaaaa tacaaaaaaa gctgaaactg taaaagctgt
    20281 agataacaca gaacctgtag atgtagatac taaaaataat attaaagaaa atcaacatgg
    20341 attagatggg gatttagata aactacataa gttaaattta gaaaatctaa acaaagaaga
    20401 tgtagacaat ttaataagaa aaaatggtat agaaaaaacc attttaatat tagctaagct
    20461 aaaagttgtt aagcttagaa atttagctcg tgaatataag gattttggaa ttgcaggtag
    20521 aacaatttca aaggcaggta aaaatttatt aattaacaaa tttaaattat attacgagaa
    20581 aaattagcta ttttaaaggt tacgaaagga agtaaggaat aatggaaaac tttgataagg
    20641 atttgcgttc aatacaacaa gcgagagatc ttgctagact tggaaaagta gcagctgata
    20701 aaattgctga ttatactgaa gagcaaattg acaaaatttt acgtaatatg gtaagagttg
    20761 cagaagaaaa cgctgtttgt ttagcacaaa tggcagttga agagacaggc tttggtaaag
    20821 ttgaagataa aactttcaaa aaccacttag cagctactat actttataat tcaattaaag
    20881 atatgaaaac tataggtgta attaatgaag ataaggaaaa taagcttata gaacttgctg
    20941 aaccagttgg cttagttatg ggtatagtac cttcaacaaa cccaacttct accgcaattt
    21001 tcaaggctat gatttcaatc aaatctcgta atgctatagt gttcgcacca catccagctg
    21061 ctgcaaaatg tacaattaaa gcagttgaat taatgaggga tgcagcaata gaagctggag
    21121 caccagaaaa cattataagt gctgtaacta ttccaacaat tggagctaca aatgaattaa
    21181 tgaaaagcaa agaagtagct ataataatag ctacaggtgg tccaggaatg gttaaagctg
    21241 cttatagctc aggaacacca gctattggtg ttggtgcagg aaactctcca gcatacattg
    21301 aaagaactgc tgatgtagaa aaagctgtta agaacattat tgcaagtaaa acttttgata
    21361 atggtacaat ctgtgcatca gaacaatcaa taatctgtga agaatgtaat catgatctag
    21421 ttgttgcaga atttaaaaaa caaggcggat acttcatgac agaagaagaa actgaaaaag
    21481 tttgcagatt attattcaaa aaaggcaatg ctatgaatgc taaatttgtt ggaagaagtc
    21541 cacaagttat agcaagtgct gcaggattca caattccagc aggaactaaa gtacttatag
    21601 gaagacaaaa tggagtagga gaaggttacc cattatcttt tgaaaaactt acaacagttc
    21661 ttggattcta tacagtaaaa gattggcatg aagcatgtga attaagtatt gaattacttc
    21721 aaaatggaat tggtcacaca atgagcatcc atactgaaga cagagatatg gttatgaagt
    21781 ttgctagaaa accagcttct cgtatccttg ttaacactgg tggaactcaa ggtggaacag
    21841 gtgcaagtac aggacttaat ccttcattta ctttaggatg cggtacttgg ggaggaagct
    21901 cagtatctga aaatgttact ccaaagcacc ttatgaacat caaaagagtt gcttatggta
    21961 taaaagattg cacaaattta gcatctaatg acccaacttt taactgcata aaaactgctg
    22021 aaaactgtca tggagttcaa aatcaattta tgaatatgag cccagcacaa attgcagcag
    22081 ctgcagaagt tttaaataag gctaataatt gcgctgaaaa cactaatact tgcactgaat
    22141 gcagtagtga aaatacaaaa aatgaagaac ttttagattt agttaatcaa atagttgccg
    22201 ctatgaaggg ggcaaactaa tggataattg tgaagaagta ttaaaacttt tactagaagc
    22261 tgttaaaagt aaagaattaa ataatgcagt taatagaaat tcatctgaga ttccagtagg
    22321 gatttctaat agacacatac atctttcaca aaaggattta gatattcttt ttggtgaaaa
    22381 ttatgggctt actaagatca aggatttatc tcaaccagga caatatgctt gcaaagaagt
    22441 tgtaacaatt tgtggaccaa agggtgcaat tgaaaaaatt agaatcttag gtcctgtaag
    22501 aagcaagact caggttgaag tattagctgg agactgcatt aagcttggat ccgtatccca
    22561 tgtaaaatta tctggagatt taaatagaac agctcctatt acaatagttg gaccaaaggg
    22621 ttctgttcaa ctagaagaag gattaatagt tgcccaaaga cacattcaca tgacacctga
    22681 agacgctaaa aatttagggg tacatgatgg agaaatagtg tcaataaaat ttgaagattt
    22741 aagaggcgga atatacaata atgtagctgt tagagctaat gacgcttcaa gccttgaatg
    22801 tcatcttgat attgaagaag ctaacgcaat gggtattaat tcaaagtcaa aagtaacaat
    22861 agtaaaataa aaaattaaat aaataattgc ttataattaa aaattaaaat aaataaaaaa
    22921 agatatttta ggaggatttt aaaatgaaat atgatgcatt aggaatgata gaaacaaaag
    22981 gattagtagg atcaatagaa gcagcagatg ctatggttaa agcagcaaac gtatatttaa
    23041 taggtaaaga atatgttgga ggcggacttg taactgttat ggttagaggt gatgttggag
    23101 ctgttaaagc tgctacagac gctggtgctg cagctgcaca acgtgttgga gaattagtat
    23161 cagttcacgt tataccacgt ccacactctg aagttgaagt aattcttcca tcatctaaag
    23221 aagttgcaaa ataagattta aaataagaaa acgccgctaa atctaattta gcggcgtttt
    23281 tacctatttt tgaaggattt atttaagtag caagaagttc ttatttattt accaaattac
    23341 tatcctttaa aagatactac taaattttat aatatttatt taccttgaaa aatttggctt
    23401 agttaaaatt atgattttta tgtatacaag taataataat attcgatata atatgttggt
    23461 ataaaattat ttcgtataaa attatttcgt ataaaattat aaggaggaaa attttatgtt
    23521 tgaaatgaaa gatgagtata gattaggaat acctagtatt gatgaggagc atgaaaaact
    23581 ttttgaaatt ggtgaaaggg catataaatt actaaaagat ccatatacta ttgataaata
    23641 tgacaagata gttgatgtaa tttcagaatt aaaggattat actgcttatc attttaaaaa
    23701 tgaagaagaa tatatgcaaa gcataaatta caaaagatta tttacccaaa aaattgagca
    23761 tgaaggtttt attaaaagac taaacgagtt agatttagat aaaattgatg aaaatcaaga
    23821 tgagtacata atggacgtgt tgaagttttt aaataattgg ataatcaatc atatagttga
    23881 gaaagattta cttattgtgt caaagtaaat aagtaatttt tagggtttca ttatttttat
    23941 attgaaaaag gaatacggtt aataatttgg tttccttaga aaattacaaa agtttcatcc
    24001 atttcaacta tcaaagagca tattatacca tccataaaag aataatcctc taggtgaaat
    24061 tgcaatttaa gtgggtaaaa gaccttataa taaaccaatt aaaaaacaga tacatataat
    24121 aattctaaag caaaataaag aggagttatt atatgttttc tatagaatac ctaataaata
    24181 taataaaaat gtttttacca cctagggctg aaattattac aatagataaa ccatataaaa
    24241 caccagcagt aggaatggta gatttagatg gaaatggcat attagaatta atagctgctt
    24301 ataagtggca aggtgaaaat tatattattg tactaaaata ttattgtggc acttggtata
    24361 tggcagatac agtgaaagga atacaatata acatatttcg gtgctgctcc agttactagt
    24421 agagataaaa ataatttagt agtgggatgg caggttggag caatatggtc agaccttagt
    24481 gtttatgaat ggacagacat gggcttagag gatttgatta atggaaataa atattttagc
    24541 cttatagagg taaaagatat taaaggtata caagggaaag atggaatata tgaactagcc
    24601 ttatggattc atgacactgg aaaggcttat aaagtggaga tatatagatg gtcaggtgat
    24661 aaatttacat tagcattaga tgtgtatcct tactatttta aaaaagtagc taactattat
    24721 aaaaaacttt taaaagaaat ggattcaaca gtctattggt attacttagc agatgctcaa
    24781 ataaaaacag gtgatattca gggggcactg gaatctatag atagggcctt agattctgaa
    24841 tacccttatc catcaaaaga agaactgata gatctaaagg cgcaaatttg tcagtatact
    24901 ccattttcaa tggtacaaca tatccaagta acccttccat tgagcctaaa gtagaatccg
    24961 gtacaaaagt acagggcata gctattgttg ctgatgatat ttctaaaaac cctggtatag
    25021 aacttaatac ttttaatagt taattatatg ttattttatc atattaggac tgagtaacaa
    25081 aaagagggcg tctcaaagta aaattagctt taattttaaa accgtaaata taaaaaatat
    25141 attcataaag cacttcattt tgctaagcaa ttcttaattt gattccatca aattaagaac
    25201 ttctaaagct tattcatatg cttattacat gtatttatta tatttaaaat taaagctatt
    25261 ttgacatagt ctctttttct gtttaaatag cttattatat ggtaatataa tagtgtaagg
    25321 agcgtgaaag ttatatgcaa aaaagattta atgtaactgg aacctgtata ccagaaaaac
    25381 actatatggt agatatatca aacaaattag atagtatatt aaagctagta aataatgaag
    25441 aatattttat tataaataga ccaagacagt atggaaaaac aactactttg tatatgttag
    25501 agaaaagatt gaatagaatg gaagaatatt tacctataaa aataagtttt gaagctatag
    25561 acacagaggg ttatagtgaa gtaaaaaaat ttttaagtag tataatgatg caaatagtta
    25621 actattttag gttttctact aacaaagaaa tttataaatt tgttaaaaat catgagaata
    25681 aaattactac tatgaatgag tttaatagtt ttataacaga tttaattgaa ttcgcagaaa
    25741 aaaaagtggt tttaataata gatgaggttg acaaaagcag taataatcaa cttttcctag
    25801 attttttagg aatgctaaga agtaaatatc tattaagaaa tgaaggaaga gactatactt
    25861 tccatagtgt gattttagca ggggtacatg acataaaaac tctaaagcta aagataagat
    25921 ctaatgaaga acataagtat aatagtccat ggaacatagc ttcggatttt gatgtagaga
    25981 tgagcttttc catagaggaa ataaaaacta tgttagatga ttatgtagaa aataaaaaag
    26041 tagatttgga taaagaatat ttttcagaaa agctttattt ttatacttca ggttatcctt
    26101 ttttagtaag taaactttgt aaaatcatag atgaaaaaat aatggatcaa aatgaattga
    26161 aatgggaaaa agaatatcta gagttagcag taaaggaact tttaaatgaa agcaatacta
    26221 attttgatag cttaattaag aatatagaaa ataacaaaga attatctgaa ttagtagata
    26281 atcttcttat aaaagggata caattaaatt ttaatattca taatccagat ataaatttag
    26341 gttatttata tggaatattt agaaatgaaa aaggaaattt aaaaataaat aataggatat
    26401 atgaacagct tatatataat tatagaatat caaaaattca aacctcatct aattttgtta
    26461 actataatag taaagaaaat tttatcgatt ctaatggaga tttaaatatt aaaaaagtac
    26521 tattaaaatt tcaagagttt atgaagcatg agtattcacg aaagagagaa gcttttttag
    26581 aagaggatgg caggttagtt ttcttagcat ttttaagtcc tattataaat ggcagtggat
    26641 ttgcatttaa agaggtaaag ggtggagaag aaaaaagatt tgatatagtt ataacctata
    26701 ataaaaaaat gtatattcta gaacttaaaa tatggagggg tgaagaatat cataaaaaag
    26761 ggttgataca gttaggagaa tacttaaatc aatatggatt ggatgaaggt taccttttaa
    26821 tatttgactt tagaaaagct gcaagcttaa taggtatagt agaagaaacc tatgtggata
    26881 tagaagagca taggaaaaaa ataatagaag tttattgcta aaataaaaat aatatattgt
    26941 gtatgtacta aaaaggcact tggttaattt caggtgcctt tttatattag aataagtaga
    27001 ttaataaaaa acatatcatt ctttaatata aatttagtta tcataaaaaa aattaataat
    27061 tttgtaagat ataatagaat ttgtaggaac tttattcttg atatggtgga agatgtaatt
    27121 atataatata tatatcaaga ataaggggga caacacaatg aaaaagaaaa taggcttaat
    27181 tatgagtatg ttattattat ttgtttttgt atttagttat actaaaaatg attatgctgt
    27241 ttatgctcaa aataatgaga caaaggtagg acaacaatta ttacaatctg aagaaggttg
    27301 gaaaagaata gaagaggata acaataactt ctcttatata aatggtaaat atacaagttg
    27361 gataaggtac tctgatatta attattctgg cggatattct atggtaccaa atgatataga
    27421 taatagtaaa gtaaatgggt atttattaaa agtaaaattt aatactgtaa cagataaaat
    27481 cagaataatt atgttttcaa gatattattg tactaacaat atagaaataa agattgatgg
    27541 aattccatat atatttgaag ctagaagcta taatcaagct aaaccgaccg tatgttttga
    27601 aaaaaaagat ttagcttata aagagcacac tgtagaaata actaatttat tagatagtaa
    27661 tataaacagt gcaatgtact ttgatgctgt agatatagat aaaaatggac agttgaaacc
    27721 ttataaagaa gctgctaaag tagagtctat atcattagat aaaacatcta tggatttatt
    27781 agaaggcagt tcagataagc taaatgctaa agtattacct gaagatgcta cgaataagaa
    27841 agtagtatgg tcatcaagtg atgaaaaaat agttacagta gataaagatg gtaaagtaac
    27901 agctatgaaa gaaggacaag caacaataac agctaaagta gaaggtactg atttaacagc
    27961 tacttgtaaa gttaacgtta ctaaaaaggt agaagaaaat aaaaataatg ctatattaag
    28021 tatatcttta gtaaatggag ctacaaaaga atatgacgta aatatgcagg aagtagagaa
    28081 gtttataaac tggtttgagg aaagatctaa tggcaaaggt tcatcattat attcatttaa
    28141 taaaaagatt aatccttata aaacagttaa agaatatata gtacatgata agatagcatc
    28201 ttttgaagta agagagtatg aaggaacaaa taaatagtta aatatcaaag agcacttaag
    28261 gaatataaac cttaggtgct ttttacatac ctaaaattga ttaggagact atattcatat
    28321 taaataaaat atgggaggtg agaggttgaa agtaggaaaa tactagaaac acaacaacca
    28381 ggaatacata agcaattaaa taaaaataga aaacagaata agaaaaagtg taggagagtt
    28441 aagaaagaaa acctctcctt ttctgatatt atgaaattaa tgcggcatga tagttataaa
    28501 aggcatagag gggcattaag acagaaataa ttgtttaaac acttagataa taattattgt
    28561 cttgcaatat attataaata ctttttacga cagttatatt aaaattaatt tggtaaaata
    28621 ttgtttaaat ggaggaattt attataatat agcgaagatt atataatata acaataattt
    28681 attatatgga gggggttaat atgaaaaaat ataagtattt aaaaagtgta ctaatgagtt
    28741 tttttatttt cactatattt tttatatgta gtgaagttaa agtacaagca atgactaata
    28801 ctgatcctca acttggttct gcgttaaaag aggttcaggt aggtgaacaa gtaaaggcaa
    28861 tagatagcag atatggttgg tggttaattg cagagaatgg taaactagct tggtgtaatg
    28921 caggcccaac atcatattgg gacaagaata cgggaaattt cccaatatta ttgagaatta
    28981 atcaaaagat gaatatacat gaagcacagg tcgtatataa ctataagaaa ggacagatta
    29041 tacaagtaat taatggttca gtaactggat ggtggaaggt taagacacca gatggatatt
    29101 atggatgggt gaatagtgct aacacgagtc gtaacagtag tggtaagttg attgctagtt
    29161 ctaatgtgag tgcttatttt acagcagata ttgccccatt acaacagatt aaagtggtac
    29221 aacctggtga acaaataaaa gctattgatt caaggacagg ttggtggatg attgcagaaa
    29281 atgatagact tggatggata agtgcagggc caacatcata ttgggataat aacactagta
    29341 cattcccact attgttaaag gctaattcta aattagcagt taatgaagtt ggaataatat
    29401 ataattattc caaaggtgaa aagattaccg tagtagaagg ttcagtagct ggatggtgga
    29461 aagttaaaac accaaatgga tattatggat ggataaatgc aaaaccaaca cattatgact
    29521 ctaataaaaa tttaatagct agtgaaaatt tacctgtata tttttcagga aaagagccaa
    29581 gtaattcaaa tgagcaatta tctaaacaac agttagtttt aagagaggct tataaacatt
    29641 taggtaaacc ttatgttaca gcaggaaaag ggccagatgc ttttgattgt tctggattca
    29701 catcttacgt atatagacat gcccttggga tagaaattgg tggatggaca ggtgcacaaa
    29761 ttaattctgg tagagaagta tctagggcag atttacagcc aggagattta gtgtttccac
    29821 attcagatca tgtaggtata tatgttggaa atggacagat gatacacgca ccataatcag
    29881 gcgatgttgt aaaagtagca cctatatata aattctggag agcaagaaga ataataaatt
    29941 aataaaaaag ggaacttctt atatggagtt ctctttttct atatctaaag gtggaagcat
    30001 aaagcagaaa acatggttta aatagggtaa gattacttaa atataattat gtaaattaaa
    30061 aataaaagta aatctaaaaa attactacaa tataacagaa ttttttaata tattaatgaa
    30121 taatatcaca atatctatta taaaaatatt aaatgattta tacagttgtc aaattattat
    30181 aaagttatgc ttctggttat tagaatataa ttttagtagg caaagataat agtaattact
    30241 gcttagaaaa attaaaaaaa gatacaaaaa aagtatctct catagacata atatatccat
    30301 tataatggag gctgttgaga ctatacagaa atgggtgata tatggtaata taatgcttat
    30361 tagagagtta aataaataat ataagaatag ataaaaagct ttcacatagt catagttttt
    30421 acagtataaa aattaaatta taatgggaga taaattatgc ataagacaat aggaatatta
    30481 gcacatgtgg atgcaggtaa aaccacattt gcagaacaaa tattatatca tacaaaaagt
    30541 attaaaatta gaggaagagt agatcataaa aactcttttt tagataatca taaaattgaa
    30601 aaagaaagag gaataacagt attttcagag cagggaacct ttaattataa agattctaca
    30661 tattatctta tagatactcc aggacatatg gatttttcat cagaaatgga aagagctatt
    30721 caggttatgg actatgctgt aattataata agtggagttg aaggaataca aggccataca
    30781 gaaacagtat ggaatctttt aagaaaacac aatattcctg ttcttttttt tataaataaa
    30841 atagatagag tgggagcaaa tgctgaaaat gtaattgaag atataaaact taattttact
    30901 aaaaaagttt gttttattga taaaccatta aatagtgatg agctttcacc tgagcttata
    30961 gaatttattg cagagcagga tgaatatctt ttagagaaat atttagaaga taattatgaa
    31021 aaagatttat ggttaaagtc tatgaaaaaa cttattaaga aaagtgagct tttcccttgt
    31081 tttataggtt cagcattaca ggatatagga atagaagatt ttttagaaaa cctacatgtt
    31141 ttaacctata cagaatacaa tgaagaagaa aaatttagtg gaagagtata taaaatacga
    31201 catgatgaag aaaacaatag attaacttat ataaaggcat taagtggcag cttaaaggta
    31261 aaagaggaga tagccttacc taatattgaa aatgattttt gtgagaaggt taatgaaata
    31321 agaatatata atggagataa atatataaat gtagataaag ctgaagcagg acagattttt
    31381 gcagtaacag gcttaagttc tgctaatata ggtgatggaa ttggaacttt aaaagataaa
    31441 gctacatata atatggttcc aactttgaaa tcaaaggtta tatttgatga aagtttaaat
    31501 gtaaaggatg ttttaaagta ttttaaaatt ttagaatcag aagatccttc tttaaatata
    31561 atctgggatg aaaaatttca agaaattcag gtttatatta tgggtgttat tcaattagaa
    31621 gtttaaaaaa acttgatgga agaaagattt ggtatatcaa tagattttgg cccttgtgaa
    31681 atattatata aggaaactat tttagataca gtaataggtt atggccattt tgaaccttta
    31741 aaacactact gtgaagttca cctaaaatta gaagcagctg agagaaatag tgggattaca
    31801 tttgaaagtg tatgtcatac agatgattta actacaggta atcaaaattt agtaaagaca
    31861 catatttttg aaagagatca tcatggaatt ttgacaggct ctcctataac agatataaag
    31921 ataacacttt taactggaag agcacataat aaacatacca gtggaggaga ttttagagag
    31981 gctactttta gagctttaag acaaggatta gaaaaagcta aaaatgtatt attagagcct
    32041 tattattctt ttaaaatgga agtgccatta gattatatgg gaagagtttt atcagatata
    32101 caaaagttaa agggagattt taatcctcca gaaacaatcc ataataaagc tattataaaa
    32161 ggaagaggac cagttgcaac atttatgaat tatagtgtag agtttatctc ttttacaaaa
    32221 ggaaagggta aatttaattt tgtatttgat gtatatgata tttgtcacaa tgaaaaagaa
    32281 gttatagaaa agatagacta tgataaaaat gcagatattg agtacacttc aacttcaatc
    32341 ttttgctcca aaggacaatc atttttagtt aaatatgatg aggtggagga atatatgcat
    32401 tgtttgaaat aaacatagag taagggggaa aaagaattac ttaaaaagtg attcttaaaa
    32461 atatatgaat aatattttag aaaattcaat tagtgatgta ttagttaaac aaatagattc
    32521 aattatggta cctagaagta ataaggtaga ttcaagaact ttctccaggt tacttgatga
    32581 tgataaagtt gttgctagct acaaaatgta ttggcttttt ggaatattag aggaagtaac
    32641 cttagaaaat actgaaatag agtttaacag aatagtagct agaatgatag tggcagcttg
    32701 gtatcctatt atgcaatata aattaagttt tggtgttttt gataatttac aaaagcctat
    32761 aaattatgtg gctttaaaat atggatttgc ttcaaattgt gatgaaagtg agtttttaaa
    32821 gttcttatgt gaaagtgaag ataaggaact taaaaaaatg atcaaggatt taacttgtat
    32881 ggttccctat agattactat ctccattttt taaagataaa cttaaaggcc aaaataagag
    32941 tagtaaaaat aaaataattc aagagctatc agtagaaagt gatacatgtt tttataagat
    33001 tattaaagaa ggcaaaaata gaatattaat aaatgaaaat tgggctcagt accttaatga
    33061 aaattataga gtaataaaat cttggatata ttataaactt gtatgttttc ttcaaaaaag
    33121 aaatcctaat gttccagcta tagcctttaa gcttgaagca cctaaaaata gagatttagc
    33181 ttcacctaca aagatttgga aagaaattat tgcttcaaag gagcctaaag acat
//