LOCUS       NZ_DS981517            23519 bp    DNA     linear   CON 30-MAR-2017
DEFINITION  Clostridium sporogenes ATCC 15579 Scfld_02_0, whole genome shotgun
            sequence.
ACCESSION   NZ_DS981517
VERSION     NZ_DS981517.1
KEYWORDS    .
SOURCE      Clostridium sporogenes ATCC 15579
  ORGANISM  Clostridium sporogenes ATCC 15579
            Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
            Clostridium.
COMMENT     REFSEQ INFORMATION: The reference sequence was derived from
            DS981517.
            Clostridium sporogenes (GenBank Accession Number for 16S rDNA gene:
            DQ911258*) is a member of the Firmicutes division of the domain
            bacteria and has been isolated from human feces. The sequenced
            strain was obtained from ATCC (ATCC 15579).
            We have collected 8.9X coverage in plasmid end reads and 454 reads.
            We have performed one round of automated sequence
            improvement(pre-finishing), along with manual improvement that
            includes breaking apart any mis-assembly, and making manual joins
            where possible. Manual edits also are made where the consensus
            appears to be incorrect. All low quality data on the ends of
            contigs is removed. Contigs are ordered and oriented where
            possible.
            Sequencing/Assembly: The genomic DNA was purified from liquid
            culture derived from a single bacterial colony. A hybrid sequencing
            strategy that utilized reads from both 454 GS-20 and ABI 3730xl
            sequencers was devised and implemented to generate the draft genome
            sequences. 454 reads were assembled using Newbler (454 Life
            Sciences) into 454 de novo contigs.These de novo contigs were
            converted in silico to 800 base paired reads ('superreads') with
            400 base overlaps with neighboring superreads. Finally, PCAP
            (Huang, et al, Genome Research, 13:2164, (2003)) was used to
            assemble the super-reads and the conventional 3730xl capillary
            reads.
            This sequenced strain is part of a comprehensive, sequence-based
            survey of members of the normal human gutmicrobiota.  A joint
            effort of the WU-GSC and the Center for Genome Sciences at
            Washington University School of Medicine, the purpose of this
            survey is to provide the general scientific community with a broad
            view of the gene content of 100 representativesof the major
            divisions represented in the intestine's microbial community. This
            information should provide a frame of reference for analyzing
            metagenomic studies of the human gut microbiome. Further details of
            this effort are described in a white paper entitled 'Extending Our
            View of Self: the Human Gut Microbiome Initiative (HGMI)'
            (http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMIS
            eq.pdf). These studies are supported by National Human Genome
            Research Institute.
            Coding sequences were predicted using GeneMark v3.3 and Glimmer2
            v2.13. Intergenic regions not spanned by GeneMark and Glimmer2 were
            blasted against NCBI's non-redundant (NR)  database and predictions
            generated based on protein alignments. tRNA genes were determined
            using tRNAscan-SE 1.23 and non-coding RNA genes by RNAmmer-1.2 and
            Rfam v8.0. Gene names are generated at the contig level and may not
            necessarily reflect any known order or orientation between contigs.
            For answers to your questions regarding this assembly or project,
            or any other GSC genome project, please visit our Genome Groups web
            page (http://genome.wustl.edu/genome_group_index.cgi) and email the
            designated contact person.
            Annotation was added to the contigs in May 2008.
            This is a reference genome for the Human Microbiome Project. This
            project is co-owned with the Human Microbiome Project DACC.
            Product names were updated in August 2012.
            Clostridium sporogenes (GenBank Accession Number for 16S rDNA gene:
            DQ911258*) is a member of the Firmicutes division of the domain
            bacteria and has been isolated from human feces. The sequenced
            strain was obtained from ATCC (ATCC 15579).
            We have collected 8.9X coverage in plasmid end reads and 454 reads.
            We have performed one round of automated sequence
            improvement(pre-finishing), along with manual improvement that
            includes breaking apart any mis-assembly, and making manual joins
            where possible. Manual edits also are made where the consensus
            appears to be incorrect. All low quality data on the ends of
            contigs is removed. Contigs are ordered and oriented where
            possible.
            Sequencing/Assembly: The genomic DNA was purified from liquid
            culture derived from a single bacterial colony. A hybrid sequencing
            strategy that utilized reads from both 454 GS-20 and ABI 3730xl
            sequencers was devised and implemented to generate the draft genome
            sequences. 454 reads were assembled using Newbler (454 Life
            Sciences) into 454 de novo contigs.These de novo contigs were
            converted in silico to 800 base paired reads ('superreads') with
            400 base overlaps with neighboring superreads. Finally, PCAP
            (Huang, et al, Genome Research, 13:2164, (2003)) was used to
            assemble the super-reads and the conventional 3730xl capillary
            reads.
            This sequenced strain is part of a comprehensive, sequence-based
            survey of members of the normal human gutmicrobiota.  A joint
            effort of the WU-GSC and the Center for Genome Sciences at
            Washington University School of Medicine, the purpose of this
            survey is to provide the general scientific community with a broad
            view of the gene content of 100 representativesof the major
            divisions represented in the intestine's microbial community. This
            information should provide a frame of reference for analyzing
            metagenomic studies of the human gut microbiome. Further details of
            this effort are described in a white paper entitled 'Extending Our
            View of Self: the Human Gut Microbiome Initiative (HGMI)'
            (http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMIS
            eq.pdf). These studies are supported by National Human Genome
            Research Institute.
            For answers to your questions regarding this assembly or project,
            or any other GSC genome project, please visit our Genome Groups web
            page (http://genome.wustl.edu/genome_group_index.cgi) and email the
            designated contact person.
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline
            set; GeneMarkS+
            repeat_region
            ##antiSMASH-Data-START##
            Version      :: 5.0.0alpha
            Run date     :: 2018-12-14 14:15:44
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2605571
            Orig. end    :: 2629090
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     cluster         1..23519
                     /aStool="rule-based-clusters"
                     /cluster_number="7"
                     /contig_edge="False"
                     /core_location="[2615571:2619090](+)"
                     /cutoff="20000"
                     /detection_rule="(minimum(6, [Fer4, Fer4_10, Fer4_6,
                     Fer4_7, PFOR_II, PGM_PMM_I, PGM_PMM_II, PGM_PMM_III,
                     PGM_PMM_IV, POR, POR_N, TPP_enzyme_C, Transketolase_C]) and
                     POR and POR_N and PFOR_II)"
                     /neighbourhood="10000"
                     /parent_cluster_number="7"
                     /product="porA"
                     /tool="antismash"
     cluster_core    10001..13519
                     /aStool="rule-based-clusters"
                     /cluster_number="7"
                     /cutoff="20000"
                     /detection_rule="(minimum(6, [Fer4, Fer4_10, Fer4_6,
                     Fer4_7, PFOR_II, PGM_PMM_I, PGM_PMM_II, PGM_PMM_III,
                     PGM_PMM_IV, POR, POR_N, TPP_enzyme_C, Transketolase_C]) and
                     POR and POR_N and PFOR_II)"
                     /neighbourhood="10000"
                     /parent_cluster_number="7"
                     /product="porA"
     supercluster    1..23519
                     /child_cluster="7"
                     /contig_edge="False"
                     /detection_rules="(minimum(6, [Fer4, Fer4_10, Fer4_6,
                     Fer4_7, PFOR_II, PGM_PMM_I, PGM_PMM_II, PGM_PMM_III,
                     PGM_PMM_IV, POR, POR_N, TPP_enzyme_C, Transketolase_C]) and
                     POR and POR_N and PFOR_II)"
                     /kind="single"
                     /product="porA"
                     /supercluster_number="7"
                     /tool="antismash"
     region          1..23519
                     /contig_edge="False"
                     /product="porA"
                     /rules="(minimum(6, [Fer4, Fer4_10, Fer4_6, Fer4_7,
                     PFOR_II, PGM_PMM_I, PGM_PMM_II, PGM_PMM_III, PGM_PMM_IV,
                     POR, POR_N, TPP_enzyme_C, Transketolase_C]) and POR and
                     POR_N and PFOR_II)"
                     /supercluster_numbers="7"
                     /tool="antismash"
     gene            1217..1831
                     /locus_tag="CLOSPO_RS12115"
                     /old_locus_tag="CLOSPO_03785"
     CDS             1217..1831
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:PF14282.4"
                     /locus_tag="CLOSPO_RS12115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03785"
                     /product="hypothetical protein"
                     /protein_id="WP_003487113.1"
                     /transl_table=11
                     /translation="MKINSTSSAPMLKQVMKNTGKDCTKNMEAEQKEIDKEIQSLQQKK
                     AALNKEIDNIKNDFAPPKPKEELIRPLKDQIQILDAQIQQKQIERTKKQNENIQEVSND
                     SDNVKSNFTLEDTEDKINPTSNNGKNKSSLKLLKNFTTQTGVINEERIKNISKNPDDPN
                     TSDSTKSITEKKRQKYFKNAIDAYNTIENSNSVNLGTNVLS"
     gene            complement(2004..2591)
                     /locus_tag="CLOSPO_RS12120"
                     /old_locus_tag="CLOSPO_03786"
     CDS             complement(2004..2591)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011099656.1"
                     /locus_tag="CLOSPO_RS12120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03786"
                     /product="hypothetical protein"
                     /protein_id="WP_003487114.1"
                     /transl_table=11
                     /translation="MITREEAWNLLNEYNKEAFHIQHALTVEGTMKYFAEKLGYEDEAE
                     FWSMVGLLHDLDFEIYPEQHCIKTQEIMRQQGLDEKLIRAAASHGYGLCLGELPKPEHQ
                     MEKVLFAVDELTGLIGAAARMRPSKSVMDMELSSLKKKFKDKKFAAGCSRDVIKQGAEM
                     LGWELNKLFEETILAMRSCEAYVNNEMEVYNN"
     gene            2828..3379
                     /locus_tag="CLOSPO_RS12125"
                     /old_locus_tag="CLOSPO_03787"
     CDS             2828..3379
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003490333.1"
                     /locus_tag="CLOSPO_RS12125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03787"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_003487117.1"
                     /transl_table=11
                     /translation="MNINSIIAENLKTLRTERNLSLGQLAELSGISKVMLSQIEKGDTN
                     PTINTLWKIAKGLKVPYTSLLEQKEHDTYVIKKRDIEAQFTEEGHYRVYCYYTSTPYRN
                     FELFQIEIDEGCSYKSIGHSKKCQEYIMVLEGELTLEVNNETYKLTPDDSISFSASNQH
                     VYINSGNGTLKATITNFYPA"
     gene            complement(3471..4916)
                     /locus_tag="CLOSPO_RS12130"
                     /old_locus_tag="CLOSPO_03788"
     CDS             complement(3471..4916)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001253726.1"
                     /locus_tag="CLOSPO_RS12130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03788"
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="WP_003487120.1"
                     /transl_table=11
                     /translation="MKTNFPENFLWGGAVAANQCEGAYNIDGKGLSVQDVAPKGIKAGP
                     TLEPTQDNMKLIGIDFYHRYKEDIKLLGEMGFKVFRLSIAWSRIFPMGDEKEANEKGLQ
                     FYDDVFDECLKYGIQPIVTLSHYETPLHLSKVYDGWKCREMIGFFNKYVCTVFNRYKNK
                     VKYWLTFNEINSITHAPFLSGGIYTPLEELSKQEIYQAIHHELVASATAVKACHEIIPD
                     AKIGCMILGMPVYPMTPSSEDMWETLNKERENFFFSDVQVRGYYPSYSKRFFKENNVKL
                     DITHEDIEILKNTVDFISFSYYMSICESSDKSIKPGEGNIIGGIPNPYLEASEWGWQID
                     PKGLRYYLNILYDRYQKPLFIVENGLGAVDELVELEDGTKIVLDDYRISYLRDHLIQVA
                     EAIEDGVDLMGYTSWGCIDLVSFTTSELKKRYGFIYVDRNDDGTGTLKRYKKKSFYWYK
                     EVISSNGDIEALCSNISIEKDKI"
     gene            complement(5216..6943)
                     /locus_tag="CLOSPO_RS12135"
                     /old_locus_tag="CLOSPO_03789"
     CDS             complement(5216..6943)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_8"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001253721.1"
                     /locus_tag="CLOSPO_RS12135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03789"
                     /product="amine oxidase"
                     /protein_id="WP_003487122.1"
                     /sec_met_domain="NAD_binding_8 (E-value: 2.8e-11, bitscore:
                     40.7, seeds: 167, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEINEFIQPNNPTYEERDNMLKSALEEVGRIEDYNNIKELLGPQA
                     DITKIISPGKGKGINVGIIGGGAAGLSSAFELRKLGFNITIFEEQKERVGGRIYTYYFD
                     KDKKMYGELGAMRIPVSHGTTWHYIDTFGLETRPFVQENENGIIYIRNKRARNDPEGKS
                     VMKNIYPEFNLSTFEKNISWQEILSYALESELDKLDTSTKKELLQIKKEYSPKIKELGA
                     ISTRKVMAGEGLSEGAIELLSYLSPIVGYFYYGSYIENLQDQYIANDYYRYYIKGGLSK
                     LPISFYNSLTSKNPKEYISISNSNLGKVKWMNGRTVTGIYKMDEKNKVRIKYREGKSLE
                     TYCEDFDYIICAIPFSSLRSVEIYPMFTPEKMQAIKELSYEAAQKTLFLCNNSFWEEGN
                     KNERIIGGSSRTDLIISSIWYPNNHLIKNIEISKNKKKHKKHKNYKSWSNPGVLLASYN
                     LNLDAVRLGNIDEKIRVELIKRQVEKVHGLPKGYLNSIVESYKTIEWDHEQGFYGGISH
                     YREEQQNLFAYASEQPEYDERVYFAGEHISQTHAWIQGALSTGMKAANRIAEHYKYKA"
     gene            complement(7353..8828)
                     /locus_tag="CLOSPO_RS12140"
                     /old_locus_tag="CLOSPO_03790"
     CDS             complement(7353..8828)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001253720.1"
                     /locus_tag="CLOSPO_RS12140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03790"
                     /product="YdiU family protein"
                     /protein_id="WP_003487124.1"
                     /transl_table=11
                     /translation="MKERKVIIKTGLNLENSYASLPEIFFTRQSPSHVPSPKLAVLNYP
                     LITSLGLNAKVLQSADGVDILAGNKTPEEAIPIAQAYAGHQFGHFTMLGDGRALLIGEH
                     ITPLGDRFDIQLKGSGKTPYSRGGDGKAALGPMLREYIISEAMNALGIPTTRSLAVVTT
                     GESITRETELPGAILTRVAASHIRVGTFEYVSRWGTVEALRALADYTLKRHFKEGNDKE
                     NPYLFLLQEIIKKQAELIAKWQLVGFIHGVMNTDNMAISGETIDYGPCAFMDAYDPETV
                     FSSIDIYGRYAYGNQPNIAAWNLARLAETLLPLLHINPNEAIKIAENAVSDFTKLYKNN
                     WLSGMRAKLGIFNEELQDEYLIEDLLSIMHKYGADYTNTFHALTFDNIEDTALFGKVEF
                     DKWYKLWQERLTRQEESKLSSKQLMKSGNPSVIPRNHRVEEALEAAVKEGDYSVMEKLL
                     DALSKPYDHSKEQDYYSKLPGPSTCPYQTYCGT"
     gene            complement(9149..9610)
                     /locus_tag="CLOSPO_RS12145"
                     /old_locus_tag="CLOSPO_03791"
     CDS             complement(9149..9610)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357140.1"
                     /locus_tag="CLOSPO_RS12145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03791"
                     /product="DUF1905 domain-containing protein"
                     /protein_id="WP_003487126.1"
                     /transl_table=11
                     /translation="MKTYTFEAEIKKIEGKDATYIEIPFDVEKEFSAKRVKVLVKFENE
                     QYRGSIVNMGLACYIIGITKEIRNKIDKTYGDIIKVELQKDEEERIVIVPEEFKVKLSN
                     NKVANDFYESLSYSYKRKYIQWLTSAKKEETKVKRMEEAIVKLENKIKI"
     gene            10001..13519
                     /locus_tag="CLOSPO_RS12150"
                     /old_locus_tag="CLOSPO_03792"
     CDS             10001..13519
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_10"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_16"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001253717.1"
                     /locus_tag="CLOSPO_RS12150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03792"
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="WP_003487127.1"
                     /sec_met_domain="PFOR_II (E-value: 2.4e-17, bitscore: 60.3,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3e-80, bitscore: 266.5,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.6e-33, bitscore: 113.4,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.5e-10, bitscore:
                     36.7, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_10 (E-value: 4.2e-08, bitscore: 30.4,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_7 (E-value: 4.1e-10, bitscore: 37.4,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_9 (E-value: 4.2e-07, bitscore: 27.3,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.4e-10, bitscore: 39.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIMKTMDGNQAAAEASYAFTEVAAIYPITPSTPMAEGVDEWSA
                     HGKKNIFGQSVKVVEMQSEAGASGTVHGSLVAGALTTTYTASQGLLLMIPNLYKIAGEL
                     LPGVFHVSARALATHALSIFGDHQDVMATRQTGVALLAASNVQEVMDLANIAHLSAIKS
                     KVPFLHFFDGFRTSHEYQKIETIDYNDVAKLVDYTALKEFKSRALNPEHPTLKGTAQNP
                     DIYFQGREASNKFYKEIPNIVENYMREIEKITGRSYHPFDYYGDPNAENIIVAMGSVCD
                     TIEETVDYLINKGEKVGVIKIHLYRPFCPTYFMKSLPKTVKKIAVLDRTKEPGSIGEPI
                     YLDICKVFYNTKDKPIIVGGRYGLGSKDTRPSQIISVFDNLNQDNPKDGFTIGITDDVT
                     NTSLPEKDVVDTTPEGTISCKFWGLGSDGTVGANKTAVKIIGDNTDLYAQAYFSYDSKK
                     SGGSTISHLRFGKDKIKSPYLIYNADYIACHNKSFIYNFDVLKGLKKNGTFVLNCPWDE
                     SELEEKLPASMKKYIAENNINFYIIDGISIAQNIGLGGRINMVMQSAFFKLANVIPVNE
                     AVELLKNSVEKTYGKKGEKIVEMNKAAIDAGIDAVHKVNIPSSWKNVETELASIKKEPD
                     FIKKIQRPISRHEGDELPVSAFNGMADGTFPLGTTSYEKRGIAVMIPEWQIDKCIQCNQ
                     CSYICPHSVIRAYLLDKDEKEKAPDTFETKKAAGKGLEDLEYRIQISSLDCTGCGNCAD
                     VCPAPGKALIMKNAEEQIEMQSENWEFGLNITTKENLMDPKTLKGSQFIRPLLEFHGAC
                     PGCGETPYIKLLTQLFGDRMMIANATGCSSIWGGSAPSVPYTTNSQGKGPSWGNSLFED
                     NAEYGYGMYLAVKQVRERLANLMQEALNMEINQNLKETFKQWLDSMDDGEGSKIATAKI
                     LETISNENYQNNPILNEIMEKKDYLIKKSHWMIGGDGWAYDIGFGGLDHVLASGDDVNI
                     FVMDTEIYSNTGGQCSKSTQTGAIAKFAAAGKKIKKKDLGLMAMSYGYVYVAQIAMGAN
                     MNHTIKTIAEAEAYKGPSLIIAYAPCISHGIKTGMGTSIAEEKKAVQSGYWHLYRYNPM
                     LKEEDKNPFILDSKEPTKPFKEFIQGEVRYSSLMNIFPDIAAKMSDMAEQHARERYDNY
                     RHLADK"
     gene            complement(13559..13726)
                     /locus_tag="CLOSPO_RS12155"
     CDS             complement(13559..13726)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001387101.1"
                     /locus_tag="CLOSPO_RS12155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3787 domain-containing protein"
                     /protein_id="WP_061329843.1"
                     /transl_table=11
                     /translation="MDKNNNKESFMAMPIEKHDTAAWANIESMKPICNVSIPSEVEVRN
                     AKEWVDTNQK"
     gene            complement(14083..15969)
                     /locus_tag="CLOSPO_RS12160"
                     /old_locus_tag="CLOSPO_03794"
     CDS             complement(14083..15969)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001253715.1"
                     /locus_tag="CLOSPO_RS12160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03794"
                     /product="glycerophosphoryl diester phosphodiesterase"
                     /protein_id="WP_003487132.1"
                     /transl_table=11
                     /translation="MTTRMETKHNKPISTLKMIRKNFTYFKKSFFINIGFESIYKVLTS
                     FIFLPFITMVLNYFMHLRGMKMMANNQILSFIGSIPGILTILILGILSFLFIFIEYAGL
                     IVISQETYFDKKISAKASFFTAMKSIRGIIKIGSIPIVIYVLFIIPFVASSMGLSSSLL
                     PKIEIPAFIMDVVYKTPKWISLYAIVFFILLYFLIRWIFSLHVVVLEGKDFFSALKRSS
                     QLVKGSFLKIWTTMFFWNLSIFAIVAVVVILVGIGMVLLNEVLKGNVKLFVTILSFVTT
                     MGGILVMIATLFIYPLTIMLITQLYYRQAKMKDGVEPTPMIITVTPSKINWQNLFNRHK
                     KKLIAVSVLGIMIFTWLSYIYFITYEFDANNNLVTVTAHRGDAVNAPDNTMSSLLSAID
                     NKADYSELDVQETKDGVVVLTHDTNLKNNTGVNKNIWELTFDEVEKLDVGSHFSPKFAG
                     EKIPTLDSIMKSANKNIKLNIEIKLNGHDQKLEERVVKLIEDNNFVDQCVVTSLDYNVL
                     QKVKNLNSRIKVGYIVFAGMGDVTALNVDFLSVEEAVATPEFIEKVHKNNKSIHVWTIN
                     DPEKMEKFIELQVDSIITDNSKEVIRLIQEKKDKQLRNEIDYIYKIVALFND"
     gene            <16235..16327
                     /locus_tag="CLOSPO_RS19420"
                     /pseudo=""
     CDS             <16235..16327
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017826477.1"
                     /locus_tag="CLOSPO_RS19420"
                     /note="incomplete; partial in the middle of a contig;
                     missing start; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="FIHHLEINTKFLGLDIEIKSKEKSAPSSQD"
     gene            complement(16397..17140)
                     /locus_tag="CLOSPO_RS12165"
                     /old_locus_tag="CLOSPO_03795"
     CDS             complement(16397..17140)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001253714.1"
                     /locus_tag="CLOSPO_RS12165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03795"
                     /product="ABC transporter permease"
                     /protein_id="WP_003487134.1"
                     /transl_table=11
                     /translation="MFKVLKNEIIKMFSGKKFYVLSGILIISIVIMSFLGKSHPQDGMN
                     ANNFVIETLFGMLMKPMVPIFMVLVIAETLTEDYIHGTMKFSLMTPIKKSDFIIGKFLF
                     IALYALIFLIVGFVGSYIVGAIAFGLGNNGDNLNLFINNIKVYASIILPLLSFSAVVSF
                     IAMIINNSGAMIGLGIGIDVIMMMIDSQMKNIMYYTFSGGMYAYRIVQNLNAHNILMLS
                     LTACIYITVFLVLSIVVVERKDIVL"
     gene            complement(17133..18056)
                     /locus_tag="CLOSPO_RS12170"
                     /old_locus_tag="CLOSPO_03796"
     CDS             complement(17133..18056)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001253713.1"
                     /locus_tag="CLOSPO_RS12170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03796"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003487136.1"
                     /transl_table=11
                     /translation="MKKKCLLSTHNLTKEYKNKKAVNNLNITVYEGDVYGFLGPNGAGK
                     STTIKSIMGLIKPTSGKVIINGYDVEKDSEKAIEKIGAMVEAPSFYGGVSGYKNLILMA
                     NLYGVPKKRVDEVLQMVRLTDVAHKNVSKYSLGMKQRLGIARAFLNNPNIVILDEPTNG
                     LDPQGIKDIRGLIQDLSKKYHVTFLISSHILSEIQAVCNRIGIIEKGSLKVEGYVEDLL
                     NKDEEVIEIYTKEKEKTSRLLKNMNISSKIQCFEGGIRIKIKKGNFQNINKLLISNDVN
                     VENLHCSETSLEDYFFNVMEGDKKYV"
     gene            complement(18305..19282)
                     /locus_tag="CLOSPO_RS12175"
                     /old_locus_tag="CLOSPO_03797"
     CDS             complement(18305..19282)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988062.1"
                     /locus_tag="CLOSPO_RS12175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03797"
                     /product="GHKL domain-containing protein"
                     /protein_id="WP_042385591.1"
                     /transl_table=11
                     /translation="MLPIIVFASLIIKRTESKKRRNKEISSSQIRSRMILMISTLLTVM
                     IASIYIFTCTSIINNQKIDFIMGNFVPEALPLISIILTSIIVYYYDKSVEYRVELRREI
                     EEKNEIEEYAHIIEEMYSETRRFKHDYINMLSPLKEYIDNEDIEGLSEFFYNNVIDMDK
                     NIKWSNSNIDKLKYIKVSGLKAILSTKLIKASSMNIDINVHIVEDIDYIHMNIMDLCRI
                     IGILMDNSIEAAGECEAPKICIAVANKNDYVVIAVHNNFFGDKPLIHKIYKEGFSTKGK
                     GRGLGLYTVKNIIDTKYENVFLNTSIEENMFIQEIWIKYIEKTS"
     gene            complement(19657..20376)
                     /locus_tag="CLOSPO_RS12180"
                     /old_locus_tag="CLOSPO_03798"
     CDS             complement(19657..20376)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001253711.1"
                     /locus_tag="CLOSPO_RS12180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03798"
                     /product="DNA-binding response regulator"
                     /protein_id="WP_003487138.1"
                     /transl_table=11
                     /translation="MLRVIICEDNEVHRDKLKQIVENTILREKLDLDVVLATESPEEII
                     SYIKENRNTGIYLLDVDLKNDINGIKLGEKIRELDPLGYIIFTTTHLEMSYLAFKYKVE
                     AMDYVIKDDDDFKERVNSCIIKAYNRYHKQEHEEEYISIDTDTRIINIRSSDILFIETT
                     GTPHKIRIHEETRQIELYANLKDMQKKLPSNFYRCHKSYIVNKDKIEEIDKKHGKIIME
                     NEEECYVSFRYMRGLLV"
     gene            20647..20859
                     /locus_tag="CLOSPO_RS12185"
                     /old_locus_tag="CLOSPO_03799"
     CDS             20647..20859
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520357.1"
                     /locus_tag="CLOSPO_RS12185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03799"
                     /product="hypothetical protein"
                     /protein_id="WP_003487139.1"
                     /transl_table=11
                     /translation="MGTKSFIITYGLPVNSESNVFDPNKLLLVVFNPVTISDLVIKPRS
                     KAKTSHELILYFEDRAFLLFGNTVQ"
     gene            complement(20937..22007)
                     /locus_tag="CLOSPO_RS12190"
                     /old_locus_tag="CLOSPO_03800"
     CDS             complement(20937..22007)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001253710.1"
                     /locus_tag="CLOSPO_RS12190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03800"
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="WP_042385322.1"
                     /transl_table=11
                     /translation="MKKKVLVGMSGGVDSSVAAYLLKEQGYEVIGVTMQIWQDDEEFIE
                     KEGGCCSLSAVADARRVANKIGIPFYVMNFKDAFKRNVIDYFVDEYMEGRTPNPCIACN
                     KFIKFSSFLDKAMAMGIDYVATGHYAIIEKHNDRYIIKKSEDDKKDQTYALYNLTQFQL
                     ERTLMPCGQYKKSKIREIAKEIGLRVHNKKDSEEICFIPDNDHGRYIKNRFPNKVREGN
                     FVDKQGNILGTHKGIVYYTIGQRKGLGIAFGKPMYVVDINPFRNEVVLGDLEDLLNTEL
                     IAKDTNYIPFDTLKEPMEVEAKIRYSQIPSKAIITTVEDGRVRVNFHEKQRAITKGQSV
                     VFYKDDLLIGGGIIEK"
     gene            complement(22122..22250)
                     /locus_tag="CLOSPO_RS12195"
                     /old_locus_tag="CLOSPO_03801"
     CDS             complement(22122..22250)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001387094.1"
                     /locus_tag="CLOSPO_RS12195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03801"
                     /product="hypothetical protein"
                     /protein_id="WP_003356573.1"
                     /transl_table=11
                     /translation="MNILKRLIKKLEKANEKEFENKKLDCCDLNKTNMVNNKPKSK"
     gene            complement(22405..23205)
                     /locus_tag="CLOSPO_RS12200"
                     /old_locus_tag="CLOSPO_03802"
     CDS             complement(22405..23205)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001253709.1"
                     /locus_tag="CLOSPO_RS12200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLOSPO_03802"
                     /product="TIGR00268 family protein"
                     /protein_id="WP_003487144.1"
                     /transl_table=11
                     /translation="MNYKYNNLINYLKDLGSVAVAFSGGVDSTLLLKAAKEALGDNVIS
                     ITVVSPYIPKWEIEEAKELANNIGIKSYFLEVPMLEEIRFNPEDRCYICKKGVFSKIKE
                     LAKEKGVKYIVDGTNLDDTKDYRPGMRALKELDVKSPLLENSINKEKIRTLSKELGLQT
                     WNKPAYACLLSRIPYNQEIKEEDLSRIEKAEVYMMELGFRAVRVRSHGDLARIEVPKKE
                     RVKLFNEDILDKVSEKFKKLGFKYVTVDTEGYKMGSLNTEINKN"
ORIGIN
        1 gtaaatgatc tgctttggtt tatactttta tgttatttgt gttatggaaa tattcttata
       61 aaactttatg ctgctattgt tccagacgca attttattgc ttatttatat tactttttta
      121 agctttgatt ttcatatttc ttcctacata aatagtttaa atataggctc tggaagagac
      181 ctttttcttc tttgcctaat aaaccttggt cgtgaactta taaatttagc tctatttttt
      241 atggttttga aaaatatttg caaattttta aatttcaaag atagaactgt aaatacctat
      301 caaagcttat atttacttat tccatgcttg gcaacttata gtttaatatt gattttctat
      361 tttgttcaag ctattcatgt tgacaataaa gactactatt tattttccat ttttcctgga
      421 atttattctg ctgtgcctct ggtaagtatt tctttattag tttctatact tatcaccgcc
      481 tacaccttta agaaaatgct tgaaggagaa gaaattcagc aaaaaaactt attaatggaa
      541 caacaattta aattgcaaat tgatcacagt aaaaatcttg agggtgttta tagtggtatt
      601 cgcagaataa tgcatgatat gaacaaccat cttatttgct taaaaaatct agctaaaagt
      661 aaaaacattg aagagataaa taactatcta gatactcttg gtcaaacaat aaataagctg
      721 gattgtaaga taaaaacagg caatgctgct tccgatgcag ttataaacga aaaatataat
      781 attgctaaac tggaaggtat tgaattcagc tgtgattttc taatacctga gggtctgaca
      841 ctaagttctg tagatttatg tatcattttg ggcaatgctt tagataatgc actggaagct
      901 tgtatgagga ttaaaaatgg aaatattcac aaagaaattt ctgttaattc ttatattaga
      961 gatctatacc taattattga ggtttcaaac agtgctacag ataaaattca gtataataag
     1021 aataaaattg tgactaaaaa aaatgataag atcaaccatg gtataggaat ttctaatata
     1081 gaaatgatag tagaaaaata taatggaatt ttagatatta tagaaggaaa aaataaattc
     1141 gttttaaatc ttatgcttaa agtaaaagaa acttaataat tccttatata ccgactgtaa
     1201 aaaggagatg ttttaaatga aaattaattc aacttcttct gctccaatgt taaaacaagt
     1261 tatgaaaaat accggtaaag attgcacaaa aaacatggaa gcagagcaaa aagaaattga
     1321 taaagaaatc caaagtcttc agcaaaagaa ggctgcttta aacaaagaaa ttgataatat
     1381 aaaaaatgac tttgcaccac ccaaacctaa ggaggaattg atcagacccc taaaagatca
     1441 aattcagatt ttagatgctc aaattcagca aaagcaaata gaaagaacaa aaaaacaaaa
     1501 tgaaaatata caggaagttt caaacgactc tgataatgtg aaatcaaatt ttactctaga
     1561 agatactgaa gataagatta accctacttc taataatgga aaaaataaat cttctcttaa
     1621 actattaaaa aacttcacta ctcaaactgg agttataaat gaggagagga taaaaaatat
     1681 ttcaaaaaat cctgatgacc ctaatacttc tgactctacg aaatccatta ctgaaaaaaa
     1741 gagacagaaa tattttaaaa atgctattga tgcatataat acaatagaaa atagtaattc
     1801 agttaatttg ggaacaaatg tgttatccta aataaaatac agttgccata cacaaactcc
     1861 atactccaaa atataaggtt atatatagat tttaatttaa gcaaatctat atataacctc
     1921 tttttagctt tatataaata tatatttaaa atttaattta gactgtattt tttagctaaa
     1981 cttctttagt atgaatatat acactaatta ttatatactt ccatttcatt attaacatat
     2041 gcttcacaag aacgcatagc taaaattgtt tcttcaaaca atttatttaa ctcccatcca
     2101 agcatctctg caccttgctt aattacatcc cgtgaacatc ccgctgcaaa tttcttatcc
     2161 ttaaattttt tcttaaggct tgaaagttcc atatccatga cactcttaga tggacgcatt
     2221 cttgcagctg caccaataag tcctgtaagt tcatctactg caaataatac tttttccatc
     2281 tgatgctctg gtttaggaag ttctcctaag caaagtccat atccatgact agctgctgcc
     2341 cttattaatt tttcatcaag accttgctgt ctcataattt cttgagtttt gatgcaatgc
     2401 tgttctggat agatttcaaa atctaaatca tgaagcaacc caaccataga ccaaaattct
     2461 gcttcatctt catatcccaa tttttctgca aaatatttca tagttccttc aactgttaaa
     2521 gcatgttgaa tatggaatgc ctctttattg tattcattaa gtaaattcca cgcttcttcc
     2581 cttgttatca taataatatc ctcctttaaa aattacaaaa tatgaataaa aatgaatctt
     2641 cactaaaata cttaagttcc ctatccttag atgcaaaaac aaaacttttc tatttattct
     2701 catttctctt gtttcattta agtaattatt atataatatt ttacgaacgt taaatatatt
     2761 tagcgttagt tttattttac ttttgttagt tataattgtc aataacatta taggaggtta
     2821 taccctaatg aatataaatt ctattattgc tgaaaacctg aaaacacttc gtactgaaag
     2881 aaatttaagt ctaggtcaac ttgctgaatt atctggtatt agtaaagtca tgctatctca
     2941 aattgaaaaa ggtgacacta atcctactat aaatacttta tggaaaatag ctaaaggatt
     3001 gaaagtgcct tatacatcat tacttgagca aaaagaacat gatacctatg ttataaagaa
     3061 aagggatatt gaagctcaat ttactgaaga agggcattat cgagtatatt gttactatac
     3121 tagtacaccc tatcgtaatt ttgaactttt tcaaattgaa attgatgaag gttgttcata
     3181 taagtctata ggtcattcta aaaaatgcca agaatatatt atggtgttag aaggtgaatt
     3241 aacattagaa gtaaacaatg aaacttataa actaactcct gatgattcaa taagtttttc
     3301 tgcatctaat caacatgtat atatcaatag tggaaatgga acattaaaag ctacaataac
     3361 aaatttttat cctgcctaat tattaggcag gatattttat gtaggtcata taaatttaat
     3421 gaaacactaa agtaataata aaaactaaaa attatttata ctatctcaaa ttatatttta
     3481 tctttttcaa tactaatatt tgaacatagt gcttcaatat ctccattact tgaaattact
     3541 tctttatacc agtaaaagct ttttttctta taacgtttta atgtccctgt tccatcatca
     3601 ttacgatcta cataaataaa tccataacgt ttctttaact cagaagtagt aaaactaact
     3661 aaatcaatgc acccccaaga agtatatccc attaagtcta ctccatcttc aattgcttct
     3721 gctacctgaa ttaaatgatc tcttaaatat gaaattctat aatcatctaa tactattttt
     3781 gtcccatctt ctagctcaac taattcatct acagctccta atccattttc aactataaat
     3841 aatggttttt gataacgatc atataatata ttaagatagt atcttaatcc tttaggatca
     3901 atttgccatc cccattcgct tgcttctaaa taagggttag gtattcctcc aataatattt
     3961 ccttcacctg gttttataga tttatcacta gactcacaaa tgctcatata ataactaaat
     4021 gaaataaaat ctacagtatt ttttaatatt tctatatctt catgtgtaat atctaactta
     4081 acattatttt ctttaaaaaa tctttttgaa tacgatggat aataaccacg tacttgaaca
     4141 tctgaaaaga aaaaattttc tctttcttta ttaagagtct cccacatatc ttctgatgat
     4201 ggtgtcattg gatatacagg catacctaaa atcatgcatc ctattttagc atcaggaata
     4261 atttcatgac atgcttttac tgctgttgca ctagctacta attcatgatg aatagcttga
     4321 tatatttctt gtttgcttaa ttcttctagt ggtgtataaa ttccaccact taaaaatggc
     4381 gcatgagtaa ttgaattaat ttcattaaag gttaaccagt attttacttt atttttatat
     4441 cgattaaaaa ctgtacaaac atacttatta aaaaatccaa tcatctcacg acatttccat
     4501 ccatcgtaaa ctttagataa atgcaatggt gtttcataat gggataatgt tactattggc
     4561 tgtattccat actttaagca ctcatcaaaa acatcatcat aaaattgtag tcccttctca
     4621 tttgcttctt tttcatcccc cattggaaat attcttgacc acgcaattga taacctaaaa
     4681 actttaaatc ccatttctcc caaaagctta atatcttctt tatatctatg ataaaaatct
     4741 atacctataa gtttcatatt atcttgtgta ggctctaatg taggaccagc ttttattccc
     4801 tttggcgcta catcttgcac gcttaatcct ttaccatcaa tattataagc tccttcacat
     4861 tggttagccg caactgcacc accccacaaa aaattttctg gaaaatttgt tttcataatt
     4921 aatcccccat attttcatta ttttttatta tatcaatagt ttcttcatct aatagtagat
     4981 tatacaaagc cgttatcttt actgtacttt aattttataa tcaacttatg ataaaatcta
     5041 tatcataaat gaatggattt ctcctacatt agataccttc ttgacaatgt gcaagaaaga
     5101 aaatggtaac ttattcattt tcatatctaa aagatatttt taatataaat acatattatc
     5161 actaaatata agcataaata aagaagcata ttaaataaaa tatacttctt tattcctaag
     5221 ctttatattt atagtgttct gctattctat tagctgcctt cataccagta cttaaagccc
     5281 cttgaatcca tgcatgtgtt tgtgatatat gctcacccgc aaaatatact ctttcatcat
     5341 actctggctg ttctgatgca tatgcaaaaa gattctgttg ttcttcccta taatgactaa
     5401 ttcctccata aaaaccttgt tcgtgatccc attctattgt tttataggat tccactattg
     5461 aattaagata tcctttaggt aaaccatgta ccttctcaac ctgtctcttt attaattcta
     5521 ctcttatctt ttcatctata ttacctaacc gtacagcatc aaggtttaga ttgtaggatg
     5581 ctaaaagcac tcccggatta ctccatgatt tataattttt atgtttttta tgcttctttt
     5641 tatttttact aatctctata tttttgataa ggtgattatt tggataccat atacttgaga
     5701 ttattaaatc tgtcctagaa ctgccaccta ttattctctc atttttattt ccttcttccc
     5761 aaaaactatt attacataga aataatgttt tttgagctgc ttcatagctt aattctttaa
     5821 ttgcttgcat tttttctgga gtaaacatag gatatatttc tacacttcga aggcttgaaa
     5881 atggtattgc acaaattata taatcaaaat cttcacaata tgtttctaaa gattttcctt
     5941 ctctatattt aattctaacc ttattttttt catccatctt ataaatccca gttactgttc
     6001 gtccattcat ccattttact tttcctaaat tagaatttga tatgcttata tactctttag
     6061 gatttttaga tgttaacgaa ttataaaaag atataggtaa tttagataac cctcctttta
     6121 tataatatct ataataatca tttgcaatat attgatcttg taaattttca atataactac
     6181 catagtaaaa ataacctaca attggagaaa gataggataa taattctata gccccctcac
     6241 ttaaaccttc acctgccata acctttcttg tacttatagc tcctaattcc tttatctttg
     6301 gagagtactc tttttttatc tgtaataatt ctttttttgt actagtatct aacttatcca
     6361 attcactttc taatgcataa ctcaaaattt cttgccatga tatatttttt tcaaaggtag
     6421 acaaattaaa ttctggatat atgttcttca ttacactttt accttctgga tcattccttg
     6481 cacgtttatt tctgatatat ataattccat tttcattttc ttgaacaaaa ggtctagttt
     6541 ctaacccaaa agtatctata taatgccaag ttgttccatg acttacaggt atacgcatag
     6601 ctccaagttc accatacatt tttttatctt tatcaaaata atacgtatat atccttcctc
     6661 caacacgttc tttttgttct tcaaaaatag ttatattaaa acccagtttt ctaagttcaa
     6721 aggcagagga taatcctgca gcacctccac ctattatccc aacattaatt cccttacctt
     6781 tacctgggga aataattttt gtaatatctg cttgaggccc aagtaattct tttatattat
     6841 tgtagtcttc tattctcccc acttcttcta atgctgactt tagcatatta tctctttcct
     6901 cataagttgg attattaggc tgtataaact catttatctc caaatagttc aaccccttaa
     6961 gttagtctta acatcaataa cttagtattc attatctaat agtattctaa atagcatttt
     7021 tttatgtcat cacattatca atgtaattat tgtaatattt aatttttaca ataatcataa
     7081 gaataatctt acaccaatta aaaaatatgg aatttgctgt aaataaaaac aaccggcaca
     7141 agttcagctg ttcttttaaa atctaatcta actaatatta gttaatatgt tattattttt
     7201 atttatttcg gttgtccaca aatacagttc atcaaaagtt tggactttcc tatatacaat
     7261 ataattaata tattttcaag ttcagagttc tattatattt ttatacaaaa agagctagta
     7321 aaacttaata tattttacta gctccttttg tattaggttc cacaataggt ttgatacgga
     7381 caagttgatg gtccaggcaa tttagagtag taatcttgtt ctttagagtg atcatatggt
     7441 tttgaaagag catctaaaag tttctccatc acactatagt ctccttcttt caccgcagcc
     7501 tctagtgctt cttctaccct gtgattacgt gggattactg atggattacc acttttcata
     7561 agctgttttg aagaaagctt tgattcttct tgtcttgtta gcctctcctg ccatagctta
     7621 taccacttat caaattccac tttaccaaac agtgccgtat cctctatatt atcaaaagtc
     7681 aatgcgtgga atgtattggt ataatctgca ccatacttat gcattatact tagaagatct
     7741 tcaattaggt attcatcctg aagctcttcg ttaaatatcc caagttttgc cctcattcca
     7801 gaaagccaat tattcttata caacttagta aaatctgaaa ccgcattttc tgctatcttt
     7861 atggcctcat ttggattaat atgcaacaat ggtaacagag tttcagcaag ccttgcaaga
     7921 ttccatgcag caatattagg ttgattacca taggcatatc taccataaat atcaatggaa
     7981 ctaaatacag tttcagggtc atatgcatcc atgaatgcac aaggaccata atcaattgtt
     8041 tctccactaa ttgccatatt atcggtattc attaccccat gaataaaacc aaccagttgc
     8101 cattttgcaa tgagctcagc ctgcttcttg attatctctt gaagtaagaa cagataagga
     8161 ttctctttat cattcccttc tttaaaatgt cttttcaaag tataatcagc tagagctcta
     8221 agcgcttcaa ctgtacccca tcttgaaacg tattcaaatg tgccaacacg tatatgactg
     8281 gcagctacac gagttaatat tgcaccgggt agctcagttt cccgcgttat tgactcacct
     8341 gttgtaacca cagctaaact acgggtggtt ggaattccta atgcattcat tgcctcactt
     8401 ataatgtatt ctcttaacat tggacctagc gctgcttttc catcgcctcc tcgtgaatat
     8461 ggagttttac ctgaaccctt aagctgaata tcaaatctat cacctagtgg agtgatgtgt
     8521 tcccctatta gcagagctct tccatcaccc aacatagtaa aatgaccaaa ttgatgtcct
     8581 gcatatgctt gagcaatagg tatagcctct tctggagtct tgtttcctgc aagtatatct
     8641 actccatcag cactttgtaa tactttggca tttagtccca aggatgttat taacggataa
     8701 ttcaatacag ctaattttgg tgaaggtaca tggctcgggc tttgtctagt aaaaaatatt
     8761 tctggaaggc tagcatagct attttctaaa ttcaagcctg tttttattat tacttttctt
     8821 tctttcattg tatctccttt tcttctctta ttttttatat aaattcttta catgaaacaa
     8881 aatcgtagtt tctattactt ttcagatata aacttctatg ataactaaac tctttttagt
     8941 ttatacttct aaaaatttat tattcccgct acatttctct ttatctccta actatttaat
     9001 aacttaatct atgaatttat attttatctc tctataatgc caatatataa taatattaat
     9061 taaatattta atataaaatt catgtaaaat ttaaaataac ccaatgtaag taataatgtt
     9121 attacttaca ttgggttata aatgaaaatt atattttaat tttattctct aatttaacta
     9181 tagcttcttc cattcttttt actttagtct cttctttttt agctgatgtt agccattgaa
     9241 tatatttacg tttataagag tatgataaag attcataaaa atcatttgct accttattat
     9301 tagaaagttt aactttaaat tcttctggta caataactat ccgttcttcc tcatcctttt
     9361 gtagttcaac ttttataata tctccataag ttttatcaat cttatttctt atctccttag
     9421 tgattccaat tatataacaa gctaatccca tatttacaat tgaacctcta tattgttcat
     9481 tttcgaattt tactaatacc ttaactcttt tggctgaaaa ctctttttca acatcgaaag
     9541 gtatctctat atatgtagca tcttttcctt caattttttt tatctctgct tcaaaagtat
     9601 aagttttcat ataagtttta atcctcctat gtaaaaatga tacatttctt tataaataga
     9661 ctatatatta tttaaaatta tattacttat tactaactca tcctttgcaa tcagattata
     9721 acataaatca atgacatttt taacattatt ggcttgtttc cttatatttc atcatattcc
     9781 atttatttgt cctccccaca gatactcttt accgtatcat aaaaaaagat ggtaagtata
     9841 aaaaatcttt ttaagctatt aagcagtaaa gttaaaggaa atttaatgac ttttctttta
     9901 gtcctctatc catatttatg ttacatgtat ttataatact ttactagtaa ataataaaca
     9961 tgtcttatta aattaaaatc ttaggaggga gaaatatttt atggcaaaaa ttatgaaaac
    10021 aatggatgga aaccaagcag ctgctgaggc atcctatgct tttactgaag ttgcagctat
    10081 ctatccaatt acaccttcca cccctatggc agaaggtgta gacgagtggt ccgctcatgg
    10141 gaaaaaaaat atatttggtc agtctgtaaa agttgttgaa atgcaatctg aagctggggc
    10201 ttctggaact gttcatggct ccttagttgc tggtgcactc acaactacat acactgcttc
    10261 tcaaggtttg ttgttaatga ttcccaatct atataaaata gctggtgaac tattacctgg
    10321 tgtatttcat gtgtctgcta gagccttagc cactcatgct ttatcaattt ttggtgatca
    10381 tcaagatgta atggctacaa gacagactgg tgtagcactt ttagcagctt caaatgttca
    10441 agaagtaatg gacttagcaa acatagcaca tctatccgct attaaatcta aagttccatt
    10501 cttacacttt tttgatggct ttagaacttc tcacgaatac caaaaaattg aaactattga
    10561 ttataatgat gtagctaaat tagtagatta tactgctcta aaagaattta aatctagggc
    10621 attaaatcca gaacatccta ctcttaaagg aactgctcaa aatccagata tttattttca
    10681 gggaagagaa gcatcaaata agttctataa agaaatacct aatattgttg aaaactacat
    10741 gcgggaaata gaaaaaatta caggaagatc ctatcatcct tttgattatt atggagatcc
    10801 taatgcagaa aatattatag ttgctatggg ttccgtatgt gatactatag aagaaacagt
    10861 agattattta ataaataaag gagaaaaagt aggcgttata aaaattcact tatatcgccc
    10921 attctgtcca acatatttta tgaaatctct acctaaaact gtaaaaaaaa ttgctgttct
    10981 tgatcgtaca aaagagcctg gttcaatagg agagcctata tatcttgata tatgtaaagt
    11041 attttataat acaaaggata agcctattat tgtaggtggt agatatggtt taggatctaa
    11101 agatacaaga ccttctcaaa ttatttcagt atttgataat ttaaatcaag ataaccctaa
    11161 ggatggattc acaataggaa ttactgatga tgttaccaat acatcattac ctgaaaagga
    11221 tgtagttgac acaactcctg agggtactat aagttgtaag ttctggggat taggttctga
    11281 tggaacagta ggtgcaaata aaactgctgt aaaaattatt ggagataata cagatttata
    11341 tgctcaggca tacttttctt atgacagtaa aaaatctggt ggtagcacca tttcccactt
    11401 aagatttgga aaggataaaa taaaatcacc ttatttaatt tataatgcag attatattgc
    11461 ttgccataac aaatccttta tatacaattt tgatgtccta aagggattaa agaaaaatgg
    11521 cacatttgta ttaaattgtc cttgggatga atcagaacta gaagaaaaac taccagcttc
    11581 tatgaaaaaa tatatagcag aaaataatat aaatttttat attattgatg gtatatctat
    11641 tgcacaaaac ataggtttag gcggtcgaat taatatggta atgcaatctg cgttctttaa
    11701 attggctaat gttatacctg taaatgaagc tgtagagctt ttaaagaatt cagttgaaaa
    11761 aacctatggt aaaaaaggtg aaaagattgt agaaatgaac aaagcagcta ttgatgcagg
    11821 tattgatgcg gtacacaagg ttaatattcc atcttcatgg aaaaatgttg aaactgaact
    11881 agcttcaata aaaaaagaac ctgacttcat aaaaaaaatt caaagaccta tatctagaca
    11941 tgaaggagat gaacttcctg ttagcgcttt taatggaatg gcagatggta ctttcccatt
    12001 aggaaccact tcttacgaaa aacgtggtat tgctgttatg attccagaat ggcaaattga
    12061 taaatgcatt caatgtaatc agtgctccta tatttgtcct cattcagtaa taagagctta
    12121 cttattagat aaagatgaaa aagaaaaggc acctgataca tttgaaacaa aaaaagctgc
    12181 tggaaaagga ttagaagatt tagaatatcg tattcaaata agttcattag attgtacagg
    12241 atgtggtaat tgtgcagatg tttgtccagc accaggtaaa gccttaatta tgaaaaatgc
    12301 ggaagaacaa attgaaatgc aatctgaaaa ctgggaattt ggtcttaata ttactactaa
    12361 agagaactta atggatccaa aaacattaaa aggcagccag tttataagac cattactaga
    12421 gtttcacgga gcttgtcctg gatgtggaga aactccatat attaaacttc taacacagct
    12481 ctttggcgat agaatgatga ttgccaatgc tactggatgt tcctcaattt ggggaggtag
    12541 tgctccatca gttccatata ctacaaattc acaaggcaaa ggcccttctt ggggtaattc
    12601 tctatttgaa gataatgctg aatatggtta tggaatgtac cttgctgtaa aacaggttag
    12661 agaaagatta gctaatttaa tgcaagaagc attaaatatg gaaattaacc agaatcttaa
    12721 agagactttt aaacaatggt tggattcaat ggatgatggt gaaggctcaa aaattgctac
    12781 agcgaaaata ctagaaacta tatcaaatga aaattatcaa aataatccta tcttaaatga
    12841 aataatggag aaaaaagact atcttataaa aaaatctcac tggatgatag gtggagatgg
    12901 ttgggcatat gatataggtt ttgggggctt agatcacgtg ttagcttctg gggatgatgt
    12961 taatatattt gtaatggata cagagatcta ttctaatact ggtggtcaat gctcgaagtc
    13021 tactcaaact ggtgctatag ctaaatttgc tgctgctggt aaaaaaatca agaaaaaaga
    13081 tctggggctt atggcaatga gttacggata tgtatatgta gctcaaatag ctatgggcgc
    13141 aaatatgaac catactatta aaacaattgc agaagcagaa gcatataaag gaccttcatt
    13201 aataattgca tatgctcctt gtattagtca tggaataaaa acaggcatgg gaacaagtat
    13261 agcagaagag aaaaaagcag tccaatcagg ttattggcat ctttatagat ataatccaat
    13321 gttaaaagaa gaagataaga atccattcat cttagattca aaagaaccaa caaaaccttt
    13381 taaagaattt attcaaggag aagttcgata ctcttctcta atgaatatat tccctgatat
    13441 tgctgcaaaa atgtcagata tggctgaaca acatgctcgt gaaagatacg acaactatag
    13501 gcatttagca gataaatagt ataaatgaaa aatagaaggg aacctataag tttcccttct
    13561 atttttgatt agtatctacc cattctttgg catttctcac ttcaacttca cttgggatag
    13621 atacattaca aataggtttc atactttcga tatttgccca cgcggcagta tcatgctttt
    13681 ctataggcat tgccataaaa ctttccttat tattgttttt atccactact atcgcaccct
    13741 tcaattatat ctttagttta ttttagtatt ccctaaatag atttacatta atctaaatct
    13801 attatatatt ttaaaattta agtcttataa tatcattgtg aattccaaac caaattatat
    13861 ggaaaatctt ctaatccata tccaattttt taaaaaatta acaatttatt tatttacctc
    13921 actacttatt ttataatttg tatgcactca tacttccatc cgaaattcaa ccacatgact
    13981 aaatttcttt ctaaggactg aataagttca gcgtgacttt tcattaacac ttatatcctt
    14041 ttttcttata taacaaatag ttcaagagtt ttaaaacttt atctagtcat taaataatgc
    14101 tacaattttg taaatataat ctatttcatt tctaagctgc ttatcttttt tctcctgaat
    14161 taaccttatt acttctttag agttatctgt aataatacta tctacttgta actctataaa
    14221 cttttccatt ttttctggat catttattgt ccaaacatga atactcttat tatttttatg
    14281 cactttctca ataaattctg gcgttgcaac ggcttcttct acacttaaga agtccacatt
    14341 caatgcagta acatctccca tacctgcaaa tacaatatat cccactttga ttctagaatt
    14401 taaatttttt accttttgca ggacattata atctaatgac gtaactacac attgatctac
    14461 aaaattattg tcctctataa gctttactac cctttcttct agcttttgat catgtccatt
    14521 cagtttaatt tctatattca gctttatatt tttattggct gatttcataa tgctgtccaa
    14581 ggttggaatt ttctcgccag caaacttagg tgaaaaatga cttcccacat ctaatttttc
    14641 tacttcatca aaggtcaatt cccaaatatt tttgtttacc cctgtattgt tctttaaatt
    14701 ggtatcgtgg gttaaaacca ccactccatc ctttgtttcc tgtacgtcta gctcactata
    14761 atctgctttg ttgtcaatag cgcttaaaag tgaactcata gtattatctg gtgcattaac
    14821 agcatctccc ctgtgagcgg taacagtaac caaattgtta ttagcatcga attcataagt
    14881 aataaaataa atataggaaa gccatgtaaa tatcattatt cctagcacac taactgctat
    14941 taattttttc ttatgtcgat taaataaatt ttgccagttt attttgcttg gtgttactgt
    15001 aataatcata ggggttggtt ctacaccatc tttcattttg gcttgtctat agtacaattg
    15061 agtaatcaac ataatagtaa gtggataaat aaataaagtg gctatcatga ctaatattcc
    15121 acccattgtt gtaacaaagg aaagaatagt tacaaatagt ttcacatttc cttttagtac
    15181 ttcatttaaa agcaccatac caattcccac taaaatcacc actactgcta caatagcaaa
    15241 aatacttaag ttccagaaaa acatagtagt ccaaatttta agaaaagatc cttttacaag
    15301 ctgtgaactc ctctttaatg cactaaaaaa atcctttcct tccaatacta caacgtgtaa
    15361 tgaaaaaatc catctaatta aaaaatataa tagtataaaa aatacaattg catataaact
    15421 tatccatttt ggtgttttgt atactacatc cataataaag gctggtattt caatcttcgg
    15481 gagtaaactt gaagacaacc ccattgaact agctacaaaa ggaataataa aaagaacata
    15541 tattacaatt ggaatagagc ctatttttat aatacctcta atacttttca ttgctgtaaa
    15601 aaaagatgct tttgctgaaa tctttttatc aaagtatgtt tcttgtgata ttacaataag
    15661 ccctgcatat tctataaaaa taaaaaggaa gctaagaatt cccaaaatta aaattgtcaa
    15721 aattcctgga atacttccta taaaacttaa tatttggtta tttgccatca tcttcatccc
    15781 tcttagatgc ataaaataat ttagcaccat tgtaataaat gggagaaata taaagcttgt
    15841 caacactttg tatatcgatt caaatccaat atttataaaa aaactctttt taaaataggt
    15901 gaaatttttt cttatcatct ttaatgtgga tatgggttta ttatgctttg tctccattct
    15961 cgttgtcatt gatctgtccc ctttacattt tctttttcaa tttagctaca ataaataccg
    16021 ctaaaattaa catacattat tatgtttttc ttatataata acaaccattt cattgttttt
    16081 aaatatgttt tttataaata atatatattt cttgtggctt tataatatat ataagattat
    16141 cttaagaagc actatacatc tttacatcta caccgtaaaa attttgtcta cccccccccc
    16201 gatgttaaaa taactatctt aagaatcaaa aaattttata catcacttag aaattaatac
    16261 taaattcctt ggtcttgata tagaaattaa aagtaaagaa aaaagtgctc catcctcaca
    16321 agattagcac tttttcttgt taacatattt cattaaaatc aatagcccta aaccaaaata
    16381 tatttcctat tgaactttat aacactatat ccttcctttc gaccacaact atactaagta
    16441 ctaagaaaac agttatatat atacatgcag taagtgaaag cattagaata ttatgggcat
    16501 ttaaattttg gacaatccta taagcataca ttcctccaga aaatgtataa tacattatat
    16561 ttttcatctg agaatctatc atcatcataa taacatcaat tccaattccc aatcctatca
    16621 ttgcaccact attattaata atcattgcaa taaaacttac aactgcgcta aaggataata
    16681 aaggtaatat tatactagca taaactttta tattattaat aaacaaattt aagttatctc
    16741 cattattccc caaaccaaaa gcgatagccc caacaatata acttccaaca aaacccacaa
    16801 ttaaaaatat taacgcatat aaagctataa ataaaaattt tccaattata aaatcacttt
    16861 tcttaatagg agtcattaat gaaaatttca tagttccatg aatataatct tctgttaatg
    16921 tttcagctat tactaacacc ataaatattg gaaccattgg tttcattagc attccaaaaa
    16981 gagtttcaat cacaaaatta tttgcattca ttccatcctg tggatgagat tttcccaaaa
    17041 aagacataat aactatactt ataatcaaaa tccctgacaa tacataaaac tttttaccac
    17101 taaacatttt tataatttca ttttttaaaa ccttaaacat attttttatc tccttccatt
    17161 acattgaaaa aataatcctc taatgaagtt tcactgcaat gtagattttc aacattaaca
    17221 tcattagaaa ttaaaagctt atttatattt tgaaaattac ccttttttat cttaattctt
    17281 ataccacctt caaaacattg aatttttgag gaaatattca tattttttaa tagacgagag
    17341 gttttctcct tttcttttgt ataaatttct attacttcct catctttatt taagagatcc
    17401 tccacataac cttcaacctt aagactcccc ttttctataa ttcctattct attacatact
    17461 gcttgaattt cacttaatat gtgtgatgat ataagaaatg ttacatgata tttttttgat
    17521 aaatcctgta taagtcccct tatatccttt attccttgag ggtctaatcc attagttggc
    17581 tcatctaata taactatatt gggattattt aaaaaagctc tcgcaattcc aagcctttgt
    17641 ttcattccta gagaatattt agacacattt ttatgagcta catcagttaa tctcaccatt
    17701 tggagtactt catctactct ttttttagga acaccatata gattagccat aagaataaga
    17761 tttttatatc ctgatactcc tccataaaag cttggtgctt ctaccatagc tcctattttc
    17821 tcaatagcct tttcactatc tttttctaca tcatatccat taataataac cttacctgaa
    17881 gtgggtttta taagtcccat aatgctcttt atggttgtac tttttcctgc tccatttggt
    17941 cctaaaaacc cataaacatc tccttcatat acagtaatat taagattatt tactgctttt
    18001 ttatttttat attctttagt aagattatga gtacttaata aacatttttt tttcatatat
    18061 aatcaactcc tcttaatatc tgttgcatat caacatacat tacttgtttt cacttgatga
    18121 ttatatacta acaaagtttt atactctatt ttttcatttc ttcctaagtg aactttagct
    18181 attcataaaa agctttattt ttacggttat gaaataaaac tttacggtta agaaaaaaga
    18241 caccttcttt taaactgccc ccaaatgtta gtcaaaaaat ctaacacttg gagatgcaat
    18301 tcaattaaga tgtcttttct atatatttta tccatatttc ctgaataaac atattctctt
    18361 caatagatgt atttaaaaat acattttcat attttgtatc tataatgttt tttacagtat
    18421 ataagcctaa gcctcttccc tttccttttg tagaaaatcc ttctttatat attttatgaa
    18481 tcaacggctt gtctccaaaa aaattattat gtactgctat aaccacataa tcatttttat
    18541 ttgcaacagc aatacatatc ttaggtgctt cacattctcc tgccgcttca atagaattat
    18601 ccataagtat tcctattatt ctacacaaat ccattatatt catatgtata taatcaatat
    18661 cttctacaat atgaacattt atgtctatat tcattgatga agcttttata agttttgttg
    18721 ataatattgc ctttagtcct gaaactttaa tatatttaag tttatctata ttactattgc
    18781 tccattttat atttttgtcc atatcaataa cgttattata aaaaaactca ctaagtcctt
    18841 ctatatcttc attatctata tattccttaa gaggtgaaag catatttata taatcatgtt
    18901 tgaatcttct tgtttcacta tacatctctt ctataatatg agcatattct tctatttcat
    18961 ttttttcttc aatttctctt cttaattcaa ccctatattc aacactttta tcataataat
    19021 aaactataat acttgtaagt ataattgata ttagtggcaa agcttctgga acaaaattgc
    19081 ccataataaa atctatcttt tgattattta ttatagaggt gcatgtaaat atataaattg
    19141 atgctatcat tacagttaat aatgtgctta tcattaaaat cattctagat cttatttggg
    19201 atgatgaaat ttctttattt ctccttttct ttgattcagt tctttttatt attaaagatg
    19261 cgaacactat aataggtaac attattataa attgaattaa tatataattt agtgatacat
    19321 tatctaatct cgcaccccaa aatgcatata taaaagcata tattgtattt gccaaataca
    19381 cactataaat actaatcaat gtttttattt tactttcatt ttcattattt cttaattgaa
    19441 caatagttat aattgaaagt ataggaagta ttaaggtata tgaaccagtt gtaagcacca
    19501 ttcctgttac aaatgaaata ataaaacatt ttttaatatt acttatattt attgtatttt
    19561 taaatagaat atatatttaa atggaacata aaatactcat tagtacagat ggtattatca
    19621 tatagcataa aatcatattt ataaacttag taaaagtcat accaagagtc ctctcatata
    19681 tctaaatgaa acataacact cttcctcatt ttccattatt atcttaccat gcttcttgtc
    19741 tatctcttca attttgtctt tgttcacaat atatgattta tgacatctat aaaaatttga
    19801 aggaagtttt ttttgcatat cctttaagtt tgcatacaat tcaatctgtc tagtttcttc
    19861 atgaatcctt attttatggg gagttcctgt agtttcaatg aatagaatat cactagatct
    19921 aatgtttatt attcgtgtat ctgtatctat tgaaatgtat tcctcttcgt gttcttgttt
    19981 atggtatcta ttataagcct ttataataca actatttact ctttctttaa aatcatcatc
    20041 atccttaatc acataatcca tagcttctac tttatattta aatgctaaat aactcatttc
    20101 taaatgagta gtagtaaata ttatatatcc taatggatct aattctctaa ttttttcccc
    20161 cagctttata ccatttatat cattttttaa atctacatcc aaaagataaa taccagtgtt
    20221 cctgttttct tttatataac ttattatttc ctcaggactt tctgtagcta gtacaacatc
    20281 taaatctaat ttttctctta aaatagtatt ctctacaatt tgcttcagtt tatctctatg
    20341 tacttcatta tcttcacaaa ttattactct taacattact tcttctcctt actttatata
    20401 aaacttcttg gtattcatat ataaacatga aaaatactaa caacattttt tcccatgaaa
    20461 gataatgttt tctttattta tattttagca aatttttata taaagtaaaa atttaaattt
    20521 taatctagat atgtaaattt cacaaataaa aaacaatttg tttattaatg cgttaataaa
    20581 cattattttt aatgttagaa aagagctaat aataatttat tgttcgactt ttaaaaaagc
    20641 aaaataatgg gaaccaaatc ttttataatt acctatggtt tacctgtaaa cagtgaatcc
    20701 aatgtatttg atcccaataa attattatta gtagtattta atccagtaac tattagtgat
    20761 ttagttataa aaccaagatc caaggctaaa acttctcatg aattaatttt atattttgag
    20821 gatagagcct tcttactctt tggaaatact gtccaataat cacatataat taaaatatat
    20881 ttaaataaaa aaagattctc aaaatagatt ttattttgag aatctctttt atttctttac
    20941 ttttcaatta ttcctccacc tattaataaa tcatctttat agaaaaccac agattgacct
    21001 ttagttatag ccctttgttt ttcatgaaaa tttaccctta ctctaccatc ttctacagta
    21061 gttattattg cctttgaagg aatttgagaa tatcttatct tagcctcaac ttccataggc
    21121 tcttttaaag tatcaaaggg tatataattt gtatccttag ctataagttc tgtatttaaa
    21181 agatcttcta aatctcctaa aactacttca tttctaaatg gatttatatc tactacatac
    21241 ataggctttc caaaagctat acctaatcct tttctttgtc ctatggtata atatactatt
    21301 cctttatgag tacctaatat attcccttgc ttatctacaa agttaccttc tctaacctta
    21361 ttaggaaatc tatttttaat ataccttcca tgatcattat ctggtatgaa gcatatttct
    21421 tcactatctt ttttattgtg aaccctaaga cctatttctt tagctatttc tctaatttta
    21481 ctttttttat actgtccaca gggcatcaag gttctttcca attgaaattg tgtaagatta
    21541 taaagagcgt aggtttgatc ttttttatcg tcttctgatt tctttattat atatctatca
    21601 ttatgctttt ctatgatagc ataatgacct gtagccacat aatctatacc catagccatg
    21661 gctttatcca gaaatgaaga aaactttata aatttattgc aggctatgca aggatttggt
    21721 gttcttcctt ccatatattc atctacaaaa taatcaataa catttctttt aaaggcatct
    21781 ttaaaattca taacataaaa aggaatgcct attttatttg ctaccctccg agcatccgct
    21841 actgcactta aagagcaaca tccaccttct ttttctataa attcctcatc atcttgccaa
    21901 atttgcatag ttactcctat aacctcataa ccctgctcct ttaaaagata cgctgctact
    21961 gaactatcta ctcctccact cataccaact aaaactttct ttttcaaaat attcacctcc
    22021 ctactaaatt attaaaatat ctatttactt attgtttttt ttaatacata ataaatagtt
    22081 tttgctttac acaattattc ttatttacta caattttaaa attacttgct tttaggctta
    22141 ttattaacca tattagtttt atttaagtca caacaatcta attttttatt ttcaaattct
    22201 ttttcattag ccttttctaa tttttttatt aatcttttaa gtatgttcat attatcacct
    22261 tacagattta tttttaatat aaatgaactt catcctaaga ctttttaaat tttatctgat
    22321 acccatatat tgtgaatttt aatgtactag gaaaatttta aatttatttt actttcctaa
    22381 ttattttctt taaactatat taaactagtt tttatttatt tcagtattta aactgcccat
    22441 cttataccct tctgtatcta cagtaacata tttaaatcct aattttttaa atttttctga
    22501 tactttatct agaatatcct cattgaacaa tttcactctt tcttttttag gcacttctat
    22561 tctagccaaa tccccatgac ttcttactct tactgctcta aatcctaact ccatcatata
    22621 tacttctgcc ttttctattc tagataaatc ttcttctttt atctcttgat tataaggaat
    22681 tctagacaaa agacaggcat aggcaggttt attccaagtt tgtaacccta gctccttaga
    22741 taaagttctt attttctctt tatttataga gttttctaag agaggacttt ttacatctaa
    22801 ttcttttaat gctctcatac ctggtctata atcttttgta tcatccaaat tagttccatc
    22861 tactatatat ttgacgccct tttcctttgc caattctttt attttactaa atacgccttt
    22921 tttacatata tagcatctgt cttctggatt aaatcttatt tcttcaagca ttggaacttc
    22981 taaaaaatat gattttattc ctatgttatt tgctaattct ttagcttctt ctatttccca
    23041 ttttggaata taaggtgata ctactgtaat ggaaataaca ttatctccta aagcttcctt
    23101 tgctgctttt aataataagg tactatctac acctccagaa aaagctactg ctacactacc
    23161 taaatccttt aaatagttaa taagattatt atatttataa ttcattttat accatcccca
    23221 tcttatattt ttgtcctatt attatgcttg ttaatatttc catctactat aaaaatcaag
    23281 tatttgtata catttttgta agttaatata aaattaagct atatagatat atttatccga
    23341 tgactacccg ctctaatact cccatcttct ttaaagtggg agtaaagagt gggtacatcc
    23401 ctggataacg atttctaagc tttagaggga gtaaaaactc cccctgaagc caagaactct
    23461 gtttataata atacaaatca tatcaattta aagattactt tactatttcc tttaatttt
//
